Nucleic Acid Related Compounds. 91. Biomimetic Reactions Are in Harmony with Loss of 2‘-Substituents as Free Radicals (Not Anions) during Mechanism-Based Inactivation of Ribonucleotide Reductases. Differential Interactions of Azide, Halogen, and Alkylthio Groups with Tributylstannane and Triphenylsilane1

Morris J. Robins; Stanislaw F. Wnuk; Amelia E. Hernández-Thirring; Mirna C. Samano

doi:10.1021/ja962117m

Nucleic Acid Related Compounds. 91. Biomimetic Reactions Are in Harmony with Loss of 2‘-Substituents as Free Radicals (Not Anions) during Mechanism-Based Inactivation of Ribonucleotide Reductases. Differential Interactions of Azide, Halogen, and Alkylthio Groups with Tributylstannane and Triphenylsilane1

Journal of the American Chemical Society ◽

10.1021/ja962117m ◽

1996 ◽

Vol 118 (46) ◽

pp. 11341-11348 ◽

Cited By ~ 10

Author(s):

Morris J. Robins ◽

Stanislaw F. Wnuk ◽

Amelia E. Hernández-Thirring ◽

Mirna C. Samano

Keyword(s):

Free Radicals ◽

Nucleic Acid ◽

Ribonucleotide Reductases ◽

Related Compounds

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ChemInform Abstract: Nucleic Acid Related Compounds. Part 95. Elimination of Chlorine (Radical) or Tosylate (Anion) from C2′ of Nucleoside C3′ Free Radicals as Model Reactions Postulated to Occur at the Active Site of Ribonucleotide Reductases.

ChemInform ◽

10.1002/chin.199733300 ◽

2010 ◽

Vol 28 (33) ◽

pp. no-no

Author(s):

M. J. ROBINS ◽

Z. GUO ◽

S. F. WNUK

Keyword(s):

Free Radicals ◽

Nucleic Acid ◽

Active Site ◽

Ribonucleotide Reductases ◽

Related Compounds ◽

Model Reactions

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ChemInform Abstract: Nucleic Acid Related Compounds. Part 75. Synthesis and Radical-Induced Ring-Opening Reactions of 2′-Deoxyadenosine-2′-spirocyclopropane and Its Uridine Analogue. Mechanistic Probes for Ribonucleotide Reductases.

ChemInform ◽

10.1002/chin.199234295 ◽

2010 ◽

Vol 23 (34) ◽

pp. no-no

Author(s):

V. SAMANO ◽

M. J. ROBINS

Keyword(s):

Nucleic Acid ◽

Ring Opening ◽

Ribonucleotide Reductases ◽

Ring Opening Reactions ◽

Related Compounds

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An electron paramagnetic resonance study of short-lived free radicals from nucleic acid constituents and related compounds in aqueous solution

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis ◽

10.1016/0005-2787(70)90074-2 ◽

1970 ◽

Vol 199 (2) ◽

pp. 316-321 ◽

Cited By ~ 12

Author(s):

Hermann Dertinger ◽

Claude Nicolau

Keyword(s):

Aqueous Solution ◽

Electron Paramagnetic Resonance ◽

Free Radicals ◽

Nucleic Acid ◽

Electron Paramagnetic Resonance Study ◽

Paramagnetic Resonance ◽

Electron Paramagnetic ◽

Related Compounds

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Pulse radiolysis of nucleic acid constituents and related compounds. III. Optical spectra and reactivity of organic free radicals formed by reaction of hydroxyl free radicals with pyrimidine bases

Journal of the American Chemical Society ◽

10.1021/ja00712a046 ◽

1970 ◽

Vol 92 (9) ◽

pp. 2875-2882 ◽

Cited By ~ 35

Author(s):

Lawrence S. Myers ◽

Mary L. Hollis ◽

Leslie M. Theard ◽

Frank C. Peterson ◽

Aida. Warnick

Keyword(s):

Free Radicals ◽

Nucleic Acid ◽

Pulse Radiolysis ◽

Optical Spectra ◽

Pyrimidine Bases ◽

Related Compounds ◽

Hydroxyl Free Radicals

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Nucleic acid and related compounds. 75. Synthesis and radical-induced ring-opening reactions of 2'-deoxyadenosine-2'-spirocyclopropane and its uridine analogs. Mechanistic probes for ribonucleotide reductases

Journal of the American Chemical Society ◽

10.1021/ja00036a077 ◽

1992 ◽

Vol 114 (10) ◽

pp. 4007-4008 ◽

Cited By ~ 31

Author(s):

Vicente Samano ◽

Morris J. Robins

Keyword(s):

Nucleic Acid ◽

Ring Opening ◽

Ribonucleotide Reductases ◽

Ring Opening Reactions ◽

Related Compounds

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Myeloperoxidase Catalyzed Bromination of Nucleic Acid Bases and Related Compounds

Bulletin of the Chemical Society of Japan ◽

10.1246/bcsj.62.3750 ◽

1989 ◽

Vol 62 (11) ◽

pp. 3750-3751 ◽

Cited By ~ 2

Author(s):

Toshio Itahara ◽

Naoko Ide

Keyword(s):

Nucleic Acid ◽

Nucleic Acid Bases ◽

Related Compounds

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THE ASSIMILATION OF NUCLEIC ACID DERIVATIVES AND RELATED COMPOUNDS BY YEASTS

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)56104-4 ◽

1951 ◽

Vol 189 (1) ◽

pp. 151-157 ◽

Cited By ~ 1

Author(s):

Frederick J. Di Carlo ◽

Alfred S. Schultz ◽

Doris K. McManus

Keyword(s):

Nucleic Acid ◽

Related Compounds

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ChemInform Abstract: NUCLEIC ACID RELATED COMPOUNDS. 37. CONVENIENT AND HIGH-YIELD SYNTHESES OF N-((2-HYDROXYETHOXY)METHYL)HETEROCYCLES AS “ACYCLIC NUCLEOSIDE” ANALOGS

Chemischer Informationsdienst ◽

10.1002/chin.198229302 ◽

1982 ◽

Vol 13 (29) ◽

Author(s):

M. J. ROBINS ◽

P. W. HATFIELD

Keyword(s):

Nucleic Acid ◽

Nucleoside Analogs ◽

High Yield ◽

Acyclic Nucleoside ◽

Related Compounds

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ChemInform Abstract: NUCLEIC ACID RELATED COMPOUNDS. 47. SYNTHESIS AND BIOLOGICAL ACTIVITIES OF PYRIMIDINE AND PURINE “ACYCLIC” NUCLEOSIDE ANALOGS

Chemischer Informationsdienst ◽

10.1002/chin.198512237 ◽

1985 ◽

Vol 16 (12) ◽

Author(s):

M. J. ROBINS ◽

P. W. HATFIELD ◽

J. BALZARINI ◽

E. DE CLERCQ

Keyword(s):

Nucleic Acid ◽

Biological Activities ◽

Nucleoside Analogs ◽

Acyclic Nucleoside ◽

Related Compounds

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Nucleic acid related compounds. 40. Synthesis and biological activities of 5-alkynyluracil nucleosides

Journal of Medicinal Chemistry ◽

10.1021/jm00359a008 ◽

1983 ◽

Vol 26 (5) ◽

pp. 661-666 ◽

Cited By ~ 74

Author(s):

Erik De Clercq ◽

Johan Descamps ◽

Jan Balzarini ◽

Jerzy Giziewicz ◽

Philip J. Barr ◽

...

Keyword(s):

Nucleic Acid ◽

Biological Activities ◽

Related Compounds

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