(−)-Sandramycin:  Total Synthesis and Characterization of DNA Binding Properties

1996 ◽  
Vol 118 (7) ◽  
pp. 1629-1644 ◽  
Author(s):  
Dale L. Boger ◽  
Jyun-Hung Chen ◽  
Kurt W. Saionz
Keyword(s):  
Dna Binding ◽  
Total Synthesis ◽  
Synthesis And Characterization ◽  
Binding Properties ◽  
Dna Binding Properties

Synthesis and characterization of Pt(ii)-based potent anticancer agents with minimum normal cell toxicity: their bio-activity and DNA-binding properties

2019 ◽  
Vol 43 (47) ◽  
pp. 18767-18779
Author(s):  
Sujay Mahata ◽  
Subhajit Mukherjee ◽  
Swarup Kumar Tarai ◽  
Angana Pan ◽  
Ishani Mitra ◽  
...  
Keyword(s):  
Cell Death ◽  
Dna Binding ◽  
Anticancer Agents ◽  
Normal Cell ◽  
Synthesis And Characterization ◽  
Cell Toxicity ◽  
Binding Properties ◽  
Anticancer Properties ◽  
Dna Binding Properties

The Cis-Pt(ii)-dichloro complex and its different intercellular derivates show good DNA-binding, comparable anticancer properties and less normal cell toxicity than cisplatin, and initiates cell death through apoptosis.

Synthesis, crystal structure and characterization of three novel copper complexes of Levofloxacin. Study of their DNA binding properties and biological activities

2014 ◽  
Vol 423 ◽  
pp. 207-218 ◽  
Author(s):  
Anastasia Galani ◽  
Eleni K. Efthimiadou ◽  
George Mitrikas ◽  
Yiannis Sanakis ◽  
Vassilis Psycharis ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Dna Binding ◽  
Copper Complexes ◽  
Biological Activities ◽  
Binding Properties ◽  
Dna Binding Properties
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