Chemical Synthesis and Biological Activity of the Neopetrosiamides and Their Analogues: Revision of Disulfide Bond Connectivity

2010 ◽  
Vol 132 (5) ◽  
pp. 1486-1487 ◽  
Author(s):  
Hongqiang Liu ◽  
Marc A. Boudreau ◽  
Jing Zheng ◽  
Randy M. Whittal ◽  
Pamela Austin ◽  
...  
Keyword(s):  
Biological Activity ◽  
Chemical Synthesis ◽  
Disulfide Bond

scholarly journals Chemical synthesis and biological activity of peptides incorporating an ether bridge as a surrogate for a disulfide bond

2020 ◽  
Vol 11 (30) ◽  
pp. 7927-7932
Author(s):  
Rui Zhao ◽  
Pan Shi ◽  
Junyou Chen ◽  
Shuaishuai Sun ◽  
Jingnan Chen ◽  
...  
Keyword(s):  
Biological Activity ◽  
Chemical Synthesis ◽  
Disulfide Bond ◽  
Ether Linkage ◽  
Ether Bridge

We report the first introduction of an ether linkage as surrogate into the disulfide-rich peptides using ether-containing diaminodiacid.

Synthesis and Biological Activity Study of Tanshinone Derivatives: A Literature and Patent Review

2020 ◽  
Vol 20 (28) ◽  
pp. 2520-2534
Author(s):  
He Huang ◽  
Chuanjun Song ◽  
Junbiao Chang
Keyword(s):  
Biological Activity ◽  
Herbal Medicine ◽  
Chemical Synthesis ◽  
Bioactive Compounds ◽  
Chinese Herbal Medicine ◽  
Salvia Miltiorrhiza ◽  
Salvia Miltiorrhiza Bunge ◽  
Chinese Herbal ◽  
Patent Review

: Tanshinones are a class of bioactive compounds present in the Chinese herbal medicine Danshen (Salvia miltiorrhiza Bunge), containing among others, abietane diterpene quinone scaffolds. Chemical synthesis and biological activity studies of natural and unnatural tanshinone derivatives have been reviewed in this article.

scholarly journals Enantioselective Catalytic C-H Amidations: An Highlight

Catalysts ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 471
Author(s):  
Eleonora Tosi ◽  
Renata Marcia de Figueiredo ◽  
Jean-Marc Campagne
Keyword(s):  
Biological Activity ◽  
Chemical Synthesis ◽  
Crucial Role ◽  
Medicinal Chemistry ◽  
Life Sciences ◽  
Biological Processes ◽  
Chiral Molecules ◽  
Material Sciences ◽  
Innovative Approaches

The crucial role played by compounds bearing amide functions, not only in biological processes but also in several fields of chemistry, life polymers and material sciences, has brought about many significant discoveries and innovative approaches for their chemical synthesis. Indeed, a plethora of strategies has been developed to reach such moieties. Amides within chiral molecules are often associated with biological activity especially in life sciences and medicinal chemistry. In most of these cases, their synthesis requires extensive rethinking methodologies. In the very last years (2019–2020), enantioselective C-H functionalization has appeared as a straightforward alternative to reach chiral amides. Therein, an overview on these transformations within this timeframe is going to be given.

scholarly journals Cordycepin analogues of 2-5A and its derivatives. Chemical synthesis and biological activity.

1983 ◽  
Vol 258 (3) ◽  
pp. 1671-1677
Author(s):  
H Sawai ◽  
J Imai ◽  
K Lesiak ◽  
M I Johnston ◽  
P F Torrence
Keyword(s):  
Biological Activity ◽  
Chemical Synthesis

Chemical Synthesis, Structural Modeling, and Biological Activity of the Epidermal Growth Factor-like Domain of HumanCripto

Biochemistry ◽  
1997 ◽  
Vol 36 (13) ◽  
pp. 3837-3845 ◽  
Author(s):  
Matthias Lohmeyer ◽  
Paul M. Harrison ◽  
Subha Kannan ◽  
Marta DeSantis ◽  
Nicola J. O'Reilly ◽  
...  
Keyword(s):  
Biological Activity ◽  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Chemical Synthesis ◽  
Structural Modeling ◽  
Epidermal Growth

Acyl Glucuronides: Biological Activity, Chemical Reactivity, and Chemical Synthesis

ChemInform ◽  
2007 ◽  
Vol 38 (14) ◽  
Author(s):  
Andrew V. Stachulski ◽  
John R. Harding ◽  
John C. Lindon ◽  
James L. Maggs ◽  
B. Kevin Park ◽  
...  
Keyword(s):  
Biological Activity ◽  
Chemical Synthesis ◽  
Chemical Reactivity ◽  
Acyl Glucuronides
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