Aromatic Cation Activation of Alcohols: Conversion to Alkyl Chlorides Using Dichlorodiphenylcyclopropene

2009 ◽  
Vol 131 (39) ◽  
pp. 13930-13931 ◽  
Author(s):  
Brendan D. Kelly ◽  
Tristan H. Lambert
Keyword(s):  
Cation Activation ◽  
Activation Of Alcohols

Designed pincer ligands supported Co(II)-based catalysts for dehydrogenative activation of alcohols: Studies on N-alkylation of amines, -alkylation of ketones and synthesis of quinolines

2021 ◽  
Author(s):  
Anshu Singh ◽  
Ankur Maji ◽  
Mayank Joshi ◽  
Angshuman Roychoudhury ◽  
Kaushik Ghosh
Keyword(s):  
Base Metal ◽  
Metal Catalysts ◽  
Pincer Ligands ◽  
Activation Of Alcohols

Base-metal catalysts Co1, Co2 and Co3 were synthesized from designed pincer ligands L1, L2 and L3 having NNN donor atoms respectively. Co1, Co2 and Co3 were characterized by IR, UV–Vis....

scholarly journals Divalent cation activation of galactosyltransferase in native mammary Golgi vesicles.

1990 ◽  
Vol 265 (26) ◽  
pp. 15731-15737 ◽  
Author(s):  
D.L. Witsell ◽  
C.E. Casey ◽  
M.C. Neville
Keyword(s):  
Divalent Cation ◽  
Golgi Vesicles ◽  
Cation Activation

Pyridine mediated transition-metal-free direct alkylation of anilines using alcohols via borrowing hydrogen conditions

2020 ◽  
Vol 56 (88) ◽  
pp. 13607-13610 ◽  
Author(s):  
Rajagopal Pothikumar ◽  
Venugopal T Bhat ◽  
Kayambu Namitharan
Keyword(s):  
Transition Metal ◽  
Traditional Approach ◽  
Metal Catalyst ◽  
Transition Metal Catalyst ◽  
Metal Free ◽  
Borrowing Hydrogen ◽  
Activation Of Alcohols ◽  
Catalyst Systems ◽  
Hydrogen Reactions

Herein, we report aza-aromatics based organic mediators as a readily accessible alternative to the traditional approach of using transition metal catalyst systems for the activation of alcohols in borrowing hydrogen reactions.

scholarly journals Phospholipid and cation activation of chimaeric choline/ethanolamine phosphotransferases

1996 ◽  
Vol 313 (3) ◽  
pp. 729-735 ◽  
Author(s):  
Christopher R. McMASTER ◽  
Sherry C. MORASH ◽  
Robert M. BELL
Keyword(s):  
Tertiary Structure ◽  
Feedback Inhibition ◽  
Head Group ◽  
Biologically Relevant ◽  
Activation Domains ◽  
Cation Activation ◽  
Absolute Requirement ◽  
Insight Into

The Saccharomyces cerevisiae CPT1 and EPT1 genes encode for a cholinephosphotransferase (CPT) and choline/ ethanolaminephosphotransferase, respectively. Both Cpt1p and Ept1p activities display an absolute requirement for cations and phospholipids. A mixed-micelle assay was employed to determine cation and lipid activators of parental and chimaeric Cpt1p/ Ept1p enzymes to gain insight into their mechanism(s) of activation. Mg2+, Mn2+ and Co2+ were the only cations capable of activating Cpt1p and Ept1p in vitro. Kinetic data revealed that only Mg2+ is present in appropriate amounts to activate CPT activity in vivo. The two enzymes displayed distinct activation profiles on the basis of their relative affinities for Mg2+, Mn2+ and Co2+. This allowed the use of chimaeric enzymes to determine the mechanism of cation activation. Cations do not activate Cpt1p or Ept1p by complexing with the substrate, CDP-choline, but instead bind to disparate regions within the enzymes themselves. Cpt1p and Ept1p also displayed distinct phospholipid activation profiles. Phospholipid activation required a phosphate and/or glycero-phosphoester linkage, with the phospho-head group moiety positioned at the surface of the micelle. Assays with parental and chimaeric Cpt1p/Ept1p constructs revealed that the phospholipid binding/activation domains are not located within linear segments of the protein, but instead are contained within distinct and separate regions of the proteins that require an intact tertiary structure for formation. Phosphatidylcholine (and its structural analogue sphingomyelin) were the best lipid activators of Cpt1p, the main biologically relevant CPT activity in S. cerevisiae. Hence CPT displays product activation. Because phosphatidylcholine is an efficient activator of CPT activity (and hence Cpt1p is not subject to feedback inhibition by its product), Cpt1p is incapable of functioning as a direct monitor of membrane phosphatidylcholine composition.

scholarly journals A Triflamide-Tethered N-Heterocyclic Carbene-Rhodium(I) Catalyst for Hydroalkoxylation Reactions: Ligand-Promoted Nucleophilic Activation of Alcohols

ChemCatChem ◽  
2017 ◽  
Vol 9 (8) ◽  
pp. 1397-1401 ◽  
Author(s):  
Abir Sarbajna ◽  
Pragati Pandey ◽  
S. M. Wahidur Rahaman ◽  
Kuldeep Singh ◽  
Akshi Tyagi ◽  
...  
Keyword(s):  
Activation Of Alcohols

H2-Generation from Alcohols by the MOF-Based Noble Metal-Free Photocatalyst Ni/CdS/TiO2@MIL-101

2019 ◽  
Vol 72 (10) ◽  
pp. 842 ◽  
Author(s):  
Dominic Tilgner ◽  
Mara Klarner ◽  
Sebastian Hammon ◽  
Martin Friedrich ◽  
Andreas Verch ◽  
...  
Keyword(s):  
Noble Metal ◽  
Metal Organic Framework ◽  
Multiple Bond ◽  
Bond Formation ◽  
Metal Free ◽  
Fossil Carbon ◽  
Gas Atmosphere ◽  
Metal Organic ◽  
Hydrogen Liberation ◽  
Activation Of Alcohols

The synthesis of important classes of chemical compounds from alcohols helps to conserve Earth’s fossil carbon resources, since alcohols can be obtained from indigestible and abundantly available biomass. The utilisation of visible light for the activation of alcohols permits alcohol-based C–N and C–C bond formation under mild conditions inaccessible with thermally operating hydrogen liberation catalysts. Herein, we report on a noble metal-free photocatalyst able to split alcohols into hydrogen and carbonyl compounds under inert gas atmosphere without the requirement of electron donors, additives, or aqueous reaction media. The reusable photocatalyst mediates C–N multiple bond formation using the oxidation of alcohols and subsequent coupling with amines. The photocatalyst consists of a CdS/TiO2 heterojunction decorated with co-catalytic Ni nanoparticles and is prepared on size-optimised colloidal metal–organic framework (MOF) crystallites.

Highly efficient iron phthalocyanine catalyzed oxidative synthesis of imines from alcohols and amines

2013 ◽  
Vol 91 (8) ◽  
pp. 732-737 ◽  
Author(s):  
Manju Bala ◽  
Praveen Kumar Verma ◽  
Neeraj Kumar ◽  
Upendra Sharma ◽  
Bikram Singh
Keyword(s):  
Lewis Acid ◽  
Oxidative Coupling ◽  
Aliphatic Alcohols ◽  
Nucleophilic Attack ◽  
Iron Phthalocyanine ◽  
Acid Base ◽  
Base Interaction ◽  
Highly Efficient ◽  
Activation Of Alcohols ◽  
Acid Base Interaction

An efficient iron phthalocyanine catalyzed method was developed for direct oxidative coupling of alcohols with amines to afford corresponding imines. The present protocol is applicable to various substituted aromatic and aliphatic alcohols and amines. The reaction is believed to proceed via activation of alcohols by iron phthalocyanines through Lewis acid–base interaction to form aldehydes, which by nucleophilic attack of amines are converted into the corresponding imines.

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