Positively Charged Base Surrogate for Highly Stable “Base Pairing” through Electrostatic and Stacking Interactions

2009 ◽  
Vol 131 (29) ◽  
pp. 9928-9930 ◽  
Author(s):  
Hiromu Kashida ◽  
Hidehiro Ito ◽  
Taiga Fujii ◽  
Takamitsu Hayashi ◽  
Hiroyuki Asanuma
Keyword(s):  
Stacking Interactions ◽  
Base Pairing ◽  
Positively Charged

Light-emitting self-assembled peptide nucleic acids exhibit both stacking interactions and Watson–Crick base pairing

2015 ◽  
Vol 10 (4) ◽  
pp. 353-360 ◽  
Author(s):  
Or Berger ◽  
Lihi Adler-Abramovich ◽  
Michal Levy-Sakin ◽  
Assaf Grunwald ◽  
Yael Liebes-Peer ◽  
...  
Keyword(s):  
Nucleic Acids ◽  
Peptide Nucleic Acids ◽  
Stacking Interactions ◽  
Base Pairing ◽  
Light Emitting ◽  
Self Assembled

Florobenzene as Artificial Nucleobases-Base Pairing and Stacking Interactions

2007 ◽  
Vol 26 (6-7) ◽  
pp. 559-562 ◽  
Author(s):  
Aleksandra Živkovic ◽  
Joachim W. Engels
Keyword(s):  
Stacking Interactions ◽  
Base Pairing

Magnetic Exchange Based on π-π Stacking Interactions: Synthesis, Crystal Structure, Thermal Decomposition and Magnetic Properties of [Ce(phen)2(H2O)2(NO3)2](NO3)(phen)2(H2O)

2002 ◽  
Vol 57 (11) ◽  
pp. 1244-1250 ◽  
Author(s):  
Yue-Qing Zheng ◽  
Lin-Xia Zhou ◽  
Jian-Li Lin ◽  
Dan-Yi Wei
Keyword(s):  
Title Compound ◽  
Magnetic Measurements ◽  
Magnetic Behavior ◽  
Water Molecules ◽  
Stacking Interactions ◽  
Magnetic Exchange ◽  
Crystal Water ◽  
Π Stacking ◽  
Nitrato Complexes ◽  
Positively Charged

Reaction of Ce(NO3)3·6H2O and 1,10-phenanthroline in CH3OH / H2O afforded the title compound [Ce(phen)2(H2O)2(NO3)2](NO3)(phen)2(H2O), which consists of [Ce(phen)2- (H2O)2(NO3)2]+ complex cations, NO3- anions, phen and crystal water molecules. Within the [Ce(phen)2(H2O)2(NO3)2]+ complex cations, the Ce atoms are 10-fold coordinated by four pyridyl N atoms, four nitrato O and two water O atoms with d(Ce-O) = 2.505 - 2.629 and d(Ce-N) = 2.666 - 2.734 Å. The supramolecular assemblies of the complex cations via π-π stacking interactions form 1D columnar chains, which run parallel to give positively charged 2D layers. The phen molecules are also assembled via π-π stacking interactions into 1D columnar chains whose arrangement results in neutral 2D layers. The NO3- anions and the crystal water molecules are situated between the positively charged and neutral 2D layers. The title compound decomposes in four steps upon heating. Magnetic measurements show that it is a ferrimagnet at low temperature and follows the Curie-Weiss law χm(T - θ) = 0.796 (cm3 mol-1 K) with the Weiss constant θ = -57(2) K over the temperature range 50 - 300 K. Comparison of the magnetic behavior of the title cerium complex with that of the Pr and Tb phen nitrato complexes of the formula Ln(phen)2(NO3)3 (Ln = Pr, Tb) suggests that magnetic exchange is probably transmitted via the π-π stacking interactions.

Protamine-DNA interaction

1978 ◽  
Vol 36 (2) ◽  
pp. 200-201
Author(s):  
D.P. Bazett-Jones ◽  
F.P. Ottensmeyer
Keyword(s):  
Small Volume ◽  
Double Helix ◽  
Dna Interaction ◽  
Dark Field ◽  
Sperm Head ◽  
Nuclear Proteins ◽  
Field Electron Microscopy ◽  
Dark Field Electron ◽  
Dna Double Helix ◽  
Positively Charged

Dark field electron microscopy has been used for the study of the structure of individual macromolecules with a resolution to at least the 5Å level. The use of this technique has been extended to the investigation of structure of interacting molecules, particularly the interaction between DNA and fish protamine, a class of basic nuclear proteins of molecular weight 4,000 daltons.Protamine, which is synthesized during spermatogenesis, binds to chromatin, displaces the somatic histones and wraps up the DNA to fit into the small volume of the sperm head. It has been proposed that protamine, existing as an extended polypeptide, winds around the minor groove of the DNA double helix, with protamine's positively-charged arginines lining up with the negatively-charged phosphates of DNA. However, viewing protamine as an extended protein is inconsistent with the results obtained in our laboratory.

Structure and Interaction of Protamine by Dark Field Electron Microscopy

1976 ◽  
Vol 34 ◽  
pp. 160-161
Author(s):  
D.P. Bazett-Jones ◽  
F.P. Ottensmeyer
Keyword(s):  
Electron Microscopy ◽  
Dark Field ◽  
Amino Acid Sequences ◽  
Dimensional Structure ◽  
3 Dimensional ◽  
Field Electron ◽  
Proposed Model ◽  
Field Electron Microscopy ◽  
Dark Field Electron ◽  
Positively Charged

It has been shown for some time that it is possible to obtain images of small unstained proteins, with a resolution of approximately 5Å using dark field electron microscopy (1,2). Applying this technique, we have observed a uniformity in size and shape of the 2-dimensional images of pure specimens of fish protamines (salmon, herring (clupeine, Y-l) and rainbow trout (Salmo irideus)). On the basis of these images, a model for the 3-dimensional structure of the fish protamines has been proposed (2).The known amino acid sequences of fish protamines show stretches of positively charged arginines, separated by regions of neutral amino acids (3). The proposed model for protamine structure (2) consists of an irregular, right-handed helix with the segments of adjacent arginines forming the loops of the coil.

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