Catalytic Asymmetric Alkylations of Ketoimines. Enantioselective Synthesis ofN-Substituted Quaternary Carbon Stereogenic Centers by Zr-Catalyzed Additions of Dialkylzinc Reagents to Aryl-, Alkyl-, and Trifluoroalkyl-Substituted Ketoimines

Peng Fu; Marc L. Snapper; Amir H. Hoveyda

doi:10.1021/ja8001343

Catalytic Asymmetric Alkylations of Ketoimines. Enantioselective Synthesis ofN-Substituted Quaternary Carbon Stereogenic Centers by Zr-Catalyzed Additions of Dialkylzinc Reagents to Aryl-, Alkyl-, and Trifluoroalkyl-Substituted Ketoimines

Journal of the American Chemical Society ◽

10.1021/ja8001343 ◽

2008 ◽

Vol 130 (16) ◽

pp. 5530-5541 ◽

Cited By ~ 151

Author(s):

Peng Fu ◽

Marc L. Snapper ◽

Amir H. Hoveyda

Keyword(s):

Enantioselective Synthesis ◽

Quaternary Carbon ◽

Stereogenic Centers ◽

Catalytic Asymmetric ◽

Asymmetric Alkylations

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ChemInform Abstract: Catalytic Asymmetric Alkylations of Ketoimines. Enantioselective Synthesis of N-Substituted Quaternary Carbon Stereogenic Centers by Zr-Catalyzed Additions of Dialkylzinc Reagents to Aryl-, Alkyl-, and Trifluoroalkyl-Substituted Ketoimines.

ChemInform ◽

10.1002/chin.200832075 ◽

2008 ◽

Vol 39 (32) ◽

Author(s):

Peng Fu ◽

Marc L. Snapper ◽

Amir H. Hoveyda

Keyword(s):

Enantioselective Synthesis ◽

Quaternary Carbon ◽

Stereogenic Centers ◽

Catalytic Asymmetric ◽

Asymmetric Alkylations

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Enantioselective Synthesis of Alkyne-Substituted Quaternary Carbon Stereogenic Centers through NHC−Cu-Catalyzed Allylic Substitution Reactions with (i-Bu)2(Alkynyl)aluminum Reagents

Journal of the American Chemical Society ◽

10.1021/ja2010829 ◽

2011 ◽

Vol 133 (13) ◽

pp. 4778-4781 ◽

Cited By ~ 105

Author(s):

Jennifer A. Dabrowski ◽

Fang Gao ◽

Amir H. Hoveyda

Keyword(s):

Enantioselective Synthesis ◽

Allylic Substitution ◽

Quaternary Carbon ◽

Substitution Reactions ◽

Stereogenic Centers

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Enantioselective Synthesis of Quaternary Carbon Stereogenic Centers through Copper-Catalyzed Conjugate Additions of Aryl- and Alkylaluminum Reagents to Acyclic Trisubstituted Enones

Angewandte Chemie International Edition ◽

10.1002/anie.201304035 ◽

2013 ◽

Vol 52 (31) ◽

pp. 8156-8159 ◽

Cited By ~ 46

Author(s):

Jennifer A. Dabrowski ◽

Matthew T. Villaume ◽

Amir H. Hoveyda

Keyword(s):

Enantioselective Synthesis ◽

Quaternary Carbon ◽

Conjugate Additions ◽

Stereogenic Centers

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Enantioselective Synthesis of All-Carbon Quaternary Stereogenic Centers by Catalytic Asymmetric Conjugate Additions of Alkyl and Aryl Aluminum Reagents to Five-, Six-, and Seven-Membered-Ring β-Substituted Cyclic Enones

Angewandte Chemie International Edition ◽

10.1002/anie.200802910 ◽

2008 ◽

Vol 47 (38) ◽

pp. 7358-7362 ◽

Cited By ~ 151

Author(s):

Tricia L. May ◽

M. Kevin Brown ◽

Amir H. Hoveyda

Keyword(s):

Membered Ring ◽

Enantioselective Synthesis ◽

Conjugate Additions ◽

Stereogenic Centers ◽

Cyclic Enones ◽

Catalytic Asymmetric ◽

Quaternary Stereogenic Centers

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Efficient catalytic asymmetric alkylations. 1. Enantioselective synthesis of (+)-indacrinone via chiral phase-transfer catalysis

Journal of the American Chemical Society ◽

10.1021/ja00314a045 ◽

1984 ◽

Vol 106 (2) ◽

pp. 446-447 ◽

Cited By ~ 345

Author(s):

Ulf H. Dolling ◽

Paul Davis ◽

Edward J. J. Grabowski

Keyword(s):

Phase Transfer Catalysis ◽

Phase Transfer ◽

Enantioselective Synthesis ◽

Chiral Phase ◽

Catalytic Asymmetric ◽

Asymmetric Alkylations

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Enantioselective Synthesis of Boron-Substituted Quaternary Carbon Stereogenic Centers through NHC-Catalyzed Conjugate Additions of (Pinacolato)boron Units to Enones

Angewandte Chemie International Edition ◽

10.1002/anie.201309982 ◽

2014 ◽

Vol 53 (13) ◽

pp. 3387-3391 ◽

Cited By ~ 75

Author(s):

Suttipol Radomkit ◽

Amir H. Hoveyda

Keyword(s):

Enantioselective Synthesis ◽

Quaternary Carbon ◽

Conjugate Additions ◽

Stereogenic Centers

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ChemInform Abstract: High Pressure Organic Chemistry. Part 40. Enantioselective Synthesis of Quaternary Carbon Stereogenic Centers Through the Primary Amine-Catalyzed Michael Addition Reaction of α-Substituted Cyclic Ketones at High Pressure.

ChemInform ◽

10.1002/chin.201546048 ◽

2015 ◽

Vol 46 (46) ◽

pp. no-no

Author(s):

Ryo Horinouchi ◽

Kouhei Kamei ◽

Riki Watanabe ◽

Nobushige Hieda ◽

Naoki Tatsumi ◽

...

Keyword(s):

Organic Chemistry ◽

High Pressure ◽

Michael Addition ◽

Primary Amine ◽

Addition Reaction ◽

Enantioselective Synthesis ◽

Quaternary Carbon ◽

Michael Addition Reaction ◽

Cyclic Ketones ◽

Stereogenic Centers

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ChemInform Abstract: Enantioselective Synthesis of Boron-Substituted Quaternary Carbon Stereogenic Centers Through NHC-Catalyzed Conjugate Additions of (Pinacolato)boron Units to Enones.

ChemInform ◽

10.1002/chin.201435027 ◽

2014 ◽

Vol 45 (35) ◽

pp. no-no

Author(s):

Suttipol Radomkit ◽

Amir H. Hoveyda

Keyword(s):

Enantioselective Synthesis ◽

Quaternary Carbon ◽

Conjugate Additions ◽

Stereogenic Centers

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Enantioselective synthesis of quaternary stereogenic centers through catalytic asymmetric addition of dimethylzinc to α-ketoesters with chiral cis-cyclopropane-based amide alcohol as ligand

Tetrahedron Asymmetry ◽

10.1016/j.tetasy.2009.07.050 ◽

2009 ◽

Vol 20 (18) ◽

pp. 2125-2129 ◽

Cited By ~ 19

Author(s):

Bing Zheng ◽

Shicong Hou ◽

Zhiyuan Li ◽

Hongchao Guo ◽

Jiangchun Zhong ◽

...

Keyword(s):

Enantioselective Synthesis ◽

Asymmetric Addition ◽

Stereogenic Centers ◽

Catalytic Asymmetric ◽

Quaternary Stereogenic Centers

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ChemInform Abstract: Enantioselective Synthesis of Alkyne-Substituted Quaternary Carbon Stereogenic Centers Through NHC-Cu-Catalyzed Allylic Substitution Reactions with (iBu)2(Alkynyl)aluminum Reagents.

ChemInform ◽

10.1002/chin.201134060 ◽

2011 ◽

Vol 42 (34) ◽

pp. no-no

Author(s):

Jennifer A. Dabrowski ◽

Fang Gao ◽

Amir H. Hoveyda

Keyword(s):

Enantioselective Synthesis ◽

Allylic Substitution ◽

Quaternary Carbon ◽

Substitution Reactions ◽

Stereogenic Centers

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