Palladium-Catalyzed Carbonylation of Aryl Tosylates and Mesylates

2008 ◽  
Vol 130 (9) ◽  
pp. 2754-2755 ◽  
Author(s):  
Rachel H. Munday ◽  
Joseph R. Martinelli ◽  
Stephen L. Buchwald
Keyword(s):  
Palladium Catalyzed ◽  
Aryl Tosylates

Dual Nickel/Palladium-Catalyzed Reductive Cross-Coupling Reactions Between Two Phenol Derivatives

2020 ◽  
Author(s):  
Baojian Xiong ◽  
Yue Li ◽  
Yin Wei ◽  
Søren Kramer ◽  
Zhong Lian
Keyword(s):  
Functional Group ◽  
Low Cost ◽  
Cross Coupling ◽  
Coupling Reactions ◽  
Phenol Derivatives ◽  
Cross Coupling Reactions ◽  
Palladium Catalyzed ◽  
One Step ◽  
Aryl Tosylates ◽  
Low Sensitivity

Cross-coupling between substrates that can be easily derived from phenols is highly attractive due to the abundance and low cost of phenols. Here, we report a dual nickel/palladium-catalyzed reductive cross-coupling between aryl tosylates and aryl triflates; both substrates can be accessed in just one step from readily available phenols. The reaction has a broad functional group tolerance and substrate scope (>60 examples). Furthermore, it displays low sensitivity to steric effects demonstrated by the synthesis of a 2,2’disubstituted biaryl and a fully substituted aryl product. The widespread presence of phenols in natural products and pharmaceuticals allow for straightforward late-stage functionalization, illustrated with examples such as Ezetimibe and tyrosine. NMR spectroscopy and DFT calculations indicate that the nickel catalyst is responsible for activating the aryl triflate, while the palladium catalyst preferentially reacts with the aryl tosylate.

Palladium-Catalyzed Direct α-Arylation of Arylacetonitriles with Aryl Tosylates and Mesylates

2020 ◽  
Vol 2020 (12) ◽  
pp. 1912-1916
Author(s):  
On Ying Yuen ◽  
Xiangmeng Chen ◽  
Junyu Wu ◽  
Chau Ming So
Keyword(s):  
Palladium Catalyzed ◽  
Aryl Tosylates

ChemInform Abstract: Palladium-Catalyzed Direct Arylation of Polyfluoroarenes with Aryl Tosylates and Mesylates.

ChemInform ◽  
2013 ◽  
Vol 44 (11) ◽  
pp. no-no
Author(s):  
Dong Sheng Lee ◽  
Pui Ying Choy ◽  
Chau Ming So ◽  
Jun Wang ◽  
Chak Po Lau ◽  
...  
Keyword(s):  
Direct Arylation ◽  
Palladium Catalyzed ◽  
Aryl Tosylates

Palladium-Catalyzed Monoarylation of Arylhydrazines with Aryl Tosylates

2020 ◽  
Vol 85 (22) ◽  
pp. 14664-14673
Author(s):  
Yange Huang ◽  
Pui Ying Choy ◽  
Junya Wang ◽  
Man-Kin Tse ◽  
Raymond Wai-Yin Sun ◽  
...  
Keyword(s):  
Palladium Catalyzed ◽  
Aryl Tosylates

ChemInform Abstract: Palladium-Catalyzed Carbonylation of Aryl Tosylates and Mesylates.

ChemInform ◽  
2008 ◽  
Vol 39 (29) ◽  
Author(s):  
Rachel H. Munday ◽  
Joseph R. Martinelli ◽  
Stephen L. Buchwald
Keyword(s):  
Palladium Catalyzed ◽  
Aryl Tosylates

Palladium-catalyzed direct arylation of polyfluoroarenes with aryl tosylates and mesylates

RSC Advances ◽  
2012 ◽  
Vol 2 (24) ◽  
pp. 9179 ◽  
Author(s):  
Dong Sheng Lee ◽  
Pui Ying Choy ◽  
Chau Ming So ◽  
Jun Wang ◽  
Chak Po Lau ◽  
...  
Keyword(s):  
Direct Arylation ◽  
Palladium Catalyzed ◽  
Aryl Tosylates

A Palladium-Catalyzed α-Arylation of Oxindoles with Aryl Tosylates

2017 ◽  
Vol 82 (12) ◽  
pp. 6468-6473 ◽  
Author(s):  
Jindian Duan ◽  
Fuk Yee Kwong
Keyword(s):  
Palladium Catalyzed ◽  
Aryl Tosylates
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