Bioactive Surface Modification of Metal Oxides via Catechol-Bearing Modular Peptides: Multivalent-Binding, Surface Retention, and Peptide Bioactivity

2014 ◽  
Vol 136 (46) ◽  
pp. 16357-16367 ◽  
Author(s):  
Wen Tang ◽  
Gina M. Policastro ◽  
Geng Hua ◽  
Kai Guo ◽  
Jinjun Zhou ◽  
...  
Keyword(s):  
Surface Modification ◽  
Metal Oxides ◽  
Binding Surface ◽  
Bioactive Surface Modification ◽  
Multivalent Binding

scholarly journals Three-Dimensional Printed Porous Titanium Screw with Bioactive Surface Modification for Bone–Tendon Healing: A Rabbit Animal Model

2020 ◽  
Vol 21 (10) ◽  
pp. 3628
Author(s):  
Yu-Min Huang ◽  
Chih-Chieh Huang ◽  
Pei-I Tsai ◽  
Kuo-Yi Yang ◽  
Shin-I Huang ◽  
...  
Keyword(s):  
Surface Modification ◽  
Tibial Tunnel ◽  
Rabbit Model ◽  
Interference Screw ◽  
Fixation Method ◽  
Titanium Screw ◽  
Pull Out ◽  
Screw Breakage ◽  
Bioactive Surface Modification ◽  
Screw Group

The interference screw fixation method is used to secure a graft in the tibial tunnel during anterior cruciate ligament reconstruction surgery. However, several complications have been reported, such as biodegradable screw breakage, inflammatory or foreign body reaction, tunnel enlargement, and delayed graft healing. Using additive manufacturing (AM) technology, we developed a titanium alloy (Ti6Al4V) interference screw with chemically calcium phosphate surface modification technology to improve bone integration in the tibial tunnel. After chemical and heat treatment, the titanium screw formed a dense apatite layer on the metal surface in simulated body fluid. Twenty-seven New Zealand white rabbits were randomly divided into control and additive manufactured (AMD) screw groups. The long digital extensor tendon was detached and translated into a tibial plateau tunnel (diameter: 2.0 mm) and transfixed with an interference screw while the paw was in dorsiflexion. Biomechanical analyses, histological analyses, and an imaging study were performed at 1, 3, and 6 months. The biomechanical test showed that the ultimate pull-out load failure was significantly higher in the AMD screw group in all tested periods. Micro-computed tomography analyses revealed early woven bone formation in the AMD screw group at 1 and 3 months. In conclusion, AMD screws with bioactive surface modification improved bone ingrowth and enhanced biomechanical performance in a rabbit model.

scholarly journals Preparation and bioactive surface modification of the microwave sintered porous Ti-15Mo alloys for biomedical application

2017 ◽  
Vol 61 (4) ◽  
pp. 545-556 ◽  
Author(s):  
Jilin Xu ◽  
Jinlong Zhang ◽  
Luzi Bao ◽  
Tao Lai ◽  
Junming Luo ◽  
...  
Keyword(s):  
Surface Modification ◽  
Biomedical Application ◽  
Porous Ti ◽  
Bioactive Surface Modification

Bioactive surface modification on amide-photografted poly(3-hydroxybutyrate- co -3-hydroxyvalerate)

2011 ◽  
Vol 6 (2) ◽  
pp. 025007 ◽  
Author(s):  
Yu Ke ◽  
Ying Jun Wang ◽  
Li Ren ◽  
Gang Wu ◽  
Wei Xue
Keyword(s):  
Surface Modification ◽  
Bioactive Surface Modification

Bioactive surface modification of Ti–29Nb–13Ta–4.6Zr alloy through alkali solution treatments

2016 ◽  
Vol 62 ◽  
pp. 662-667 ◽  
Author(s):  
E. Takematsu ◽  
K. Katsumata ◽  
K. Okada ◽  
M. Niinomi ◽  
N. Matsushita
Keyword(s):  
Surface Modification ◽  
Alkali Solution ◽  
Bioactive Surface Modification
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