Synthesis of (±)-Actinophyllic Acid and Analogs: Applications of Cascade Reactions and Diverted Total Synthesis

2013 ◽  
Vol 135 (35) ◽  
pp. 12984-12986 ◽  
Author(s):  
Brett A. Granger ◽  
Ivan T. Jewett ◽  
Jeffrey D. Butler ◽  
Bruce Hua ◽  
Claire E. Knezevic ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Cascade Reactions ◽  
Actinophyllic Acid

ChemInform Abstract: Cascade Reactions: A Driving Force in Akuammiline Alkaloid Total Synthesis

ChemInform ◽  
2015 ◽  
Vol 46 (12) ◽  
pp. no-no
Author(s):  
Joel M. Smith ◽  
Jesus Moreno ◽  
Ben W. Boal ◽  
Neil K. Garg
Keyword(s):  
Total Synthesis ◽  
Driving Force ◽  
Cascade Reactions

Diversity-Oriented Synthesis of Natural Products via Gold-Catalyzed Cascade Reactions

Synlett ◽  
2018 ◽  
Vol 29 (12) ◽  
pp. 1552-1571 ◽  
Author(s):  
Jianxian Gong ◽  
Zhen Yang ◽  
Yueqing Gu ◽  
Ceheng Tan
Keyword(s):  
Natural Products ◽  
Total Synthesis ◽  
Cascade Reactions ◽  
Cascade Reaction ◽  
Biologically Active ◽  
Synthetic Methods ◽  
Left Wing ◽  
Asymmetric Total Synthesis ◽  
Diversity Oriented Synthesis ◽  
Active Natural

This account describes our group’s latest research in the field of diversity-oriented synthesis of natural products via gold-catalyzed cascade reactions. We present two general strategies based on gold-catalyzed cycloisomerization: a gold-catalyzed cascade reaction of 1,7-diynes and a pinacol-terminated gold-catalyzed cascade reaction. We highlight our development of synthetic methods for the construction of biologically active natural products by using these two strategies.1 Introduction2 Gold-Catalyzed Cascade Reactions of 1,7-Diynes2.1 Collective Synthesis of C15 Oxygenated Drimane-Type Sesquiterpenoids2.2 Synthesis of Left-Wing Fragment of Azadirachtin I2.3 Collective Synthesis of Cladiellins3 Pinacol-Terminated Gold-Catalyzed Cascade Reaction3.1 Asymmetric Formal Total Synthesis of (+)-Cortistatins3.2 Total Synthesis of Orientalol F3.3 Asymmetric Total Synthesis of (–)-Farnesiferol C4 Summary and Outlook

Organocatalytic cascade reactions as a new tool in total synthesis

2010 ◽  
Vol 2 (3) ◽  
pp. 167-178 ◽  
Author(s):  
Christoph Grondal ◽  
Matthieu Jeanty ◽  
Dieter Enders
Keyword(s):  
Total Synthesis ◽  
Cascade Reactions

Total Synthesis of (+)-Rugulosin and (+)-2,2′-epi-Cytoskyrin A through Cascade Reactions

2005 ◽  
Vol 44 (48) ◽  
pp. 7917-7921 ◽  
Author(s):  
K. C. Nicolaou ◽  
Yee Hwee Lim ◽  
Charles D. Papageorgiou ◽  
Jared L. Piper
Keyword(s):  
Total Synthesis ◽  
Cascade Reactions

Cascade Reactions Involving Formal [2+2] Thermal Cycloadditions: Total Synthesis of Artochamins F, H, I, and J

2007 ◽  
Vol 46 (39) ◽  
pp. 7501-7505 ◽  
Author(s):  
K. C. Nicolaou ◽  
Troy Lister ◽  
Ross M. Denton ◽  
Christine F. Gelin
Keyword(s):  
Total Synthesis ◽  
Cascade Reactions

Progress Toward the Total Synthesis of (±)-Actinophyllic Acid

2009 ◽  
Vol 11 (20) ◽  
pp. 4532-4535 ◽  
Author(s):  
Rishi G. Vaswani ◽  
Joshua J. Day ◽  
John L. Wood
Keyword(s):  
Total Synthesis ◽  
Actinophyllic Acid

Total Synthesis of (+)-Rugulosin and (+)-2,2′-epi-Cytoskyrin A Through Cascade Reactions.

ChemInform ◽  
2006 ◽  
Vol 37 (16) ◽  
Author(s):  
K. C. Nicolaou ◽  
Yee Hwee Lim ◽  
Charles D. Papageorgiou ◽  
Jared L. Piper
Keyword(s):  
Total Synthesis ◽  
Cascade Reactions

Cascade Reactions Involving Formal [2+2] Thermal Cycloadditions: Total Synthesis of Artochamins F, H, I, and J

2007 ◽  
Vol 119 (39) ◽  
pp. 7645-7649 ◽  
Author(s):  
K. C. Nicolaou ◽  
Troy Lister ◽  
Ross M. Denton ◽  
Christine F. Gelin
Keyword(s):  
Total Synthesis ◽  
Cascade Reactions
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