Graphene Oxide/Nucleic-Acid-Stabilized Silver Nanoclusters: Functional Hybrid Materials for Optical Aptamer Sensing and Multiplexed Analysis of Pathogenic DNAs

2013 ◽  
Vol 135 (32) ◽  
pp. 11832-11839 ◽  
Author(s):  
Xiaoqing Liu ◽  
Fuan Wang ◽  
Ruth Aizen ◽  
Omer Yehezkeli ◽  
Itamar Willner
Keyword(s):  
Graphene Oxide ◽  
Nucleic Acid ◽  
Hybrid Materials ◽  
Silver Nanoclusters ◽  
Multiplexed Analysis

Graphene oxide/silver nanoclusters based logic devices and their application to multiplexed analysis of miRNA

2018 ◽  
Vol 273 ◽  
pp. 408-417 ◽  
Author(s):  
Siqi Zhang ◽  
Wei Shi ◽  
Kai-Bin Li ◽  
Fengzao Chen ◽  
Jie Su ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Silver Nanoclusters ◽  
Logic Devices ◽  
Multiplexed Analysis

scholarly journals Polyethylene Glycol Functionalized Graphene Oxide Nanoparticles Loaded with Nigella sativa Extract: A Smart Antibacterial Therapeutic Drug Delivery System

Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3067
Author(s):  
Mustafa A. Jihad ◽  
Farah T. M. Noori ◽  
Majid S. Jabir ◽  
Salim Albukhaty ◽  
Faizah A. AlMalki ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Grain Size ◽  
Cell Wall ◽  
Graphene Oxide ◽  
Polyethylene Glycol ◽  
Nucleic Acid ◽  
Drug Delivery System ◽  
Delivery System ◽  
Nigella Sativa ◽  
Seed Extract

Flaky graphene oxide (GO) nanoparticles (NPs) were synthesized using Hummer’s method and then capped with polyethylene glycol (PEG) by an esterification reaction, then loaded with Nigella sativa (N. sativa) seed extract. Aiming to investigate their potential use as a smart drug delivery system against Staphylococcus aureus and Escherichia coli, the spectral and structural characteristics of GO-PEG NPs were comprehensively analyzed by XRD, AFM, TEM, FTIR, and UV- Vis. XRD patterns revealed that GO-PEG had different crystalline structures and defects, as well as a higher interlayer spacing. AFM results showed GONPs with the main grain size of 24.41 nm, while GONPs–PEG revealed graphene oxide aggregation with the main grain size of 287.04 nm after loading N. sativa seed extract, which was verified by TEM examination. A strong OH bond appeared in FTIR spectra. Furthermore, UV- Vis absorbance peaks at (275, 284, 324, and 327) nm seemed to be correlated with GONPs, GO–PEG, N. sativa seed extract, and GO –PEG- N. sativa extract. The drug delivery system was observed to destroy the bacteria by permeating the bacterial nucleic acid and cytoplasmic membrane, resulting in the loss of cell wall integrity, nucleic acid damage, and increased cell-wall permeability.

Silver nanocluster-lightened hybridization chain reaction

RSC Advances ◽  
2016 ◽  
Vol 6 (62) ◽  
pp. 57502-57506 ◽  
Author(s):  
Lin Liu ◽  
Qing Li ◽  
Li-Juan Tang ◽  
Ru-Qin Yu ◽  
Jian-Hui Jiang
Keyword(s):  
Nucleic Acid ◽  
Silver Nanoclusters ◽  
Hybridization Chain Reaction ◽  
Label Free ◽  
Chain Reaction ◽  
Silver Nanocluster ◽  
Turn On ◽  
Nucleic Acid Assays

A hybridization chain reaction (HCR) lightened by DNA-stabilized silver nanoclusters (AgNCs) as a label-free and turn on fluorescence platform for nucleic acid assays.

Aptasensors based on supramolecular structures of nucleic acid-stabilized Ag nanoclusters

2015 ◽  
Vol 51 (6) ◽  
pp. 1100-1103 ◽  
Author(s):  
Etery Sharon ◽  
Natalie Enkin ◽  
H. Bauke Albada ◽  
Itamar Willner
Keyword(s):  
Nucleic Acid ◽  
Supramolecular Structures ◽  
Luminescence Detection ◽  
Ag Nanoclusters ◽  
Ag Ncs ◽  
Multiplexed Analysis

A supramolecular DNA nanocluster consisting of Ag NCs allows the luminescence detection and multiplexed analysis of ligand–aptamer complexes.

Framework nucleic acid programmed combinatorial delivery nanocarriers for parallel and multiplexed analysis

2021 ◽  
Author(s):  
Yinghui Feng ◽  
Qi Liu ◽  
Miao Chen ◽  
Xinyi Zhao ◽  
Lumin Wang ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Multiplexed Analysis

Herein we report a framework nucleic acid programmed strategy to develop nanocarriers to precisely and independently package multiple homo- and heterogeneous cargos in vitro and in vivo, thereby enabling multiplexed...

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