Heterobimetallic Carbene Complexes by a Single-Step Site-Selective Metalation of a Tricarbene Ligand

2013 ◽  
Vol 135 (13) ◽  
pp. 4966-4969 ◽  
Author(s):  
Ramananda Maity ◽  
Hannah Koppetz ◽  
Alexander Hepp ◽  
F. Ekkehardt Hahn
Keyword(s):  
Single Step ◽  
Carbene Complexes ◽  
Site Selective ◽  
Step Site

Thermal field desorption spectroscopy of chemisorbed hydrogen for a single step site

1993 ◽  
Vol 71 (6) ◽  
pp. 891-894 ◽  
Author(s):  
N. Ernst ◽  
J. H. Block ◽  
H. J. Kreuzer ◽  
X. Ye
Keyword(s):  
Thermal Field ◽  
Single Step ◽  
Field Desorption ◽  
Step Site

Nitrilotriacetic Acid-Derivatized Quantum Dots for Simple Purification and Site-Selective Fluorescent Labeling of Active Proteins in a Single Step

2008 ◽  
Vol 19 (10) ◽  
pp. 1964-1967 ◽  
Author(s):  
Manish Gupta ◽  
Anne Caniard ◽  
Ángeles Touceda-Varela ◽  
Dominic J. Campopiano ◽  
Juan C. Mareque-Rivas
Keyword(s):  
Quantum Dots ◽  
Nitrilotriacetic Acid ◽  
Single Step ◽  
Fluorescent Labeling ◽  
Site Selective

A Multifunctional Reagent Designed for the Site-Selective Amination of Pyridines

2020 ◽  
Author(s):  
Patrick Fier ◽  
Suhong Kim ◽  
Ryan Cohen
Keyword(s):  
Reaction Mechanism ◽  
Direct Conversion ◽  
Single Step ◽  
The Novel ◽  
Title Reaction ◽  
Mild Conditions ◽  
Unique Reaction ◽  
Unexpected Findings ◽  
Site Selective

We report the development of a multifunctional reagent for the direct conversion of pyridines to Boc-protected 2-aminopyridines with exquisite site- and chemoselectivity. The novel reagent was prepared on 200 gram-scale in a single step, reacts in the title reaction under mild conditions without precautions towards air or moisture, and is tolerant of nearly all common functionality. Experimental and <i>in-situ </i>spectroscopic<i> </i>monitoring techniques provide detailed insights and unexpected findings for the unique reaction mechanism.

A Multifunctional Reagent Designed for the Site-Selective Amination of Pyridines

2020 ◽  
Author(s):  
Patrick Fier ◽  
Suhong Kim ◽  
Ryan Cohen
Keyword(s):  
Reaction Mechanism ◽  
Direct Conversion ◽  
Single Step ◽  
The Novel ◽  
Title Reaction ◽  
Mild Conditions ◽  
Unique Reaction ◽  
Unexpected Findings ◽  
Site Selective

We report the development of a multifunctional reagent for the direct conversion of pyridines to Boc-protected 2-aminopyridines with exquisite site- and chemoselectivity. The novel reagent was prepared on 200 gram-scale in a single step, reacts in the title reaction under mild conditions without precautions towards air or moisture, and is tolerant of nearly all common functionality. Experimental and <i>in-situ </i>spectroscopic<i> </i>monitoring techniques provide detailed insights and unexpected findings for the unique reaction mechanism.

scholarly journals Site-selective carbon–carbon bond formation in unprotected monosaccharides using photoredox catalysis

2017 ◽  
Vol 53 (36) ◽  
pp. 4926-4929 ◽  
Author(s):  
Ieng Chim (Steven) Wan ◽  
Martin D. Witte ◽  
Adriaan J. Minnaard
Keyword(s):  
Bond Formation ◽  
Photoredox Catalysis ◽  
Carbon Bond ◽  
Selective Protection ◽  
Carbon Carbon Bond ◽  
One Step ◽  
Site Selective ◽  
Step Site

One-step site-selective, protection group-free synthesis of branched monosaccharides.

One-Pot, Single-Step, and Gram-Scale Synthesis of Mononuclear [(η6-arene)Ni(N-heterocyclic carbene)] Complexes: Useful Precursors of the Ni0–NHC Unit

2014 ◽  
Vol 33 (5) ◽  
pp. 1276-1282 ◽  
Author(s):  
Yoichi Hoshimoto ◽  
Yukari Hayashi ◽  
Haruka Suzuki ◽  
Masato Ohashi ◽  
Sensuke Ogoshi
Keyword(s):  
Single Step ◽  
One Pot ◽  
Carbene Complexes

Mechanochemical changes on cyclometalated Ir(iii) acyclic carbene complexes – design and tuning of luminescent mechanochromic transition metal complexes

2020 ◽  
Vol 7 (3) ◽  
pp. 786-794 ◽  
Author(s):  
Jingqi Han ◽  
Kin-Man Tang ◽  
Shun-Cheung Cheng ◽  
Chi-On Ng ◽  
Yuen-Kiu Chun ◽  
...  
Keyword(s):  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Carbene Complexes ◽  
New Class

A new class of luminescent cyclometalated Ir(iii) complexes with readily tunable mechanochromic properties derived from the mechanically induced trans-to-cis isomerization have been developed.

V884: Demonstration of a Novel Single-Step Percutaneous Access Sheath for Nephrostolithotomy: A Video Presentation

2005 ◽  
Vol 173 (4S) ◽  
pp. 240-240
Author(s):  
Premal J. Desai ◽  
David A. Hadley ◽  
Lincoln J. Maynes ◽  
D. Duane Baldwin
Keyword(s):  
Single Step ◽  
Video Presentation ◽  
Percutaneous Access ◽  
Access Sheath

Effect of Lipoprotein(a) and LDL on Plasminogen Binding to Extracellular Matrix and on Matrix-dependent Plasminogen Activation by Tissue Plasminogen Activator

1996 ◽  
Vol 75 (03) ◽  
pp. 497-502 ◽  
Author(s):  
Hadewijch L M Pekelharing ◽  
Henne A Kleinveld ◽  
Pieter F C.C.M Duif ◽  
Bonno N Bouma ◽  
Herman J M van Rijn
Keyword(s):  
Extracellular Matrix ◽  
Endothelial Cells ◽  
Plasminogen Activator ◽  
Binding Sites ◽  
Umbilical Vein ◽  
Single Step ◽  
Plasminogen Activation ◽  
Structural Homology ◽  
Tissue Plasminogen ◽  
Umbilical Vein Endothelial Cells

SummaryLp(a) is an LDL-like lipoprotein plus an additional apolipoprotein apo(a). Based on the structural homology of apo(a) with plasminogen, it is hypothesized that Lp(a) interferes with fibrinolysis. Extracellular matrix (ECM) produced by human umbilical vein endothelial cells was used to study the effect of Lp(a) and LDL on plasminogen binding and activation. Both lipoproteins were isolated from the same plasma in a single step. Plasminogen bound to ECM via its lysine binding sites. Lp(a) as well as LDL were capable of competing with plasminogen binding. The degree of inhibition was dependent on the lipoprotein donor as well as the ECM donor. When Lp(a) and LDL obtained from one donor were compared, Lp(a) was always a much more potent competitor. The effect of both lipoproteins on plasminogen binding was reflected in their effect on plasminogen activation. It is speculated that Lp(a) interacts with ECM via its LDL-like lipoprotein moiety as well as via its apo(a) moiety.

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