Lab in a Tube: Ultrasensitive Detection of MicroRNAs at the Single-Cell Level and in Breast Cancer Patients Using Quadratic Isothermal Amplification

2013 ◽  
Vol 135 (12) ◽  
pp. 4604-4607 ◽  
Author(s):  
Ruixue Duan ◽  
Xiaolei Zuo ◽  
Shutao Wang ◽  
Xiyun Quan ◽  
Dongliang Chen ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Single Cell ◽  
Cancer Patients ◽  
Isothermal Amplification ◽  
Ultrasensitive Detection ◽  
Single Cell Level ◽  
Breast Cancer Patients ◽  
Cell Level

scholarly journals Heterogeneity of PIK3CA mutational status at the single cell level in circulating tumor cells from metastatic breast cancer patients

2014 ◽  
Vol 9 (4) ◽  
pp. 749-757 ◽  
Author(s):  
Marta Pestrin ◽  
Francesca Salvianti ◽  
Francesca Galardi ◽  
Francesca De Luca ◽  
Natalie Turner ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Metastatic Breast Cancer ◽  
Single Cell ◽  
Cancer Patients ◽  
Tumor Cells ◽  
Metastatic Breast ◽  
Single Cell Level ◽  
Breast Cancer Patients ◽  
Cell Level ◽  
Mutational Status

Label-free and ultrasensitive detection of polynucleotide kinase activity at the single-cell level

2018 ◽  
Vol 54 (13) ◽  
pp. 1583-1586 ◽  
Author(s):  
Meng Liu ◽  
Fei Ma ◽  
Qianyi Zhang ◽  
Chun-yang Zhang
Keyword(s):  
Single Cell ◽  
Kinase Activity ◽  
Fluorescence Method ◽  
Kinase Assay ◽  
Ultrasensitive Detection ◽  
Single Cell Level ◽  
Label Free ◽  
Cell Level ◽  
Polynucleotide Kinase

We develop a label-free fluorescence method for the polynucleotide kinase assay at the single-cell level based on phosphorylation-triggered isothermal exponential amplification.

DNA-fueled molecular machine for label-free and non-enzymatic ultrasensitive detection of telomerase activity

The Analyst ◽  
2016 ◽  
Vol 141 (16) ◽  
pp. 4855-4858 ◽  
Author(s):  
Panpan Sun ◽  
Xiang Ran ◽  
Chaoqun Liu ◽  
Chaoying Liu ◽  
Fang Pu ◽  
...  
Keyword(s):  
Single Cell ◽  
Cancer Cell ◽  
Telomerase Activity ◽  
Molecular Machine ◽  
Ultrasensitive Detection ◽  
Single Cell Level ◽  
Label Free ◽  
Enzymatic Method ◽  
Cell Level ◽  
Cell Extracts

A label-free and non-enzymatic method based on DNA-fueled molecular machine has been introduced for ultrasensitive detection of telomerase activity in cancer cell extracts even at the single-cell level.

Ultrasensitive Detection of Telomerase Activity at the Single-Cell Level

2013 ◽  
Vol 85 (23) ◽  
pp. 11509-11517 ◽  
Author(s):  
Li-juan Wang ◽  
Yan Zhang ◽  
Chun-yang Zhang
Keyword(s):  
Single Cell ◽  
Telomerase Activity ◽  
Ultrasensitive Detection ◽  
Single Cell Level ◽  
Cell Level
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