Unmediated by DNA Electron Transfer in Redox-Labeled DNA Duplexes End-Tethered to Gold Electrodes

2012 ◽  
Vol 134 (35) ◽  
pp. 14499-14507 ◽  
Author(s):  
Alireza Abi ◽  
Elena E. Ferapontova
Keyword(s):  
Electron Transfer ◽  
Gold Electrodes ◽  
Dna Duplexes

scholarly journals DNA-Mediated Electron Transfer in DNA Duplexes Tethered to Gold Electrodes via Phosphorothioated dA Tags

Langmuir ◽  
2014 ◽  
Vol 30 (40) ◽  
pp. 11853-11857 ◽  
Author(s):  
Rui Campos ◽  
Alexander Kotlyar ◽  
Elena E. Ferapontova
Keyword(s):  
Electron Transfer ◽  
Gold Electrodes ◽  
Dna Duplexes ◽  
Mediated Electron Transfer

scholarly journals Redox-Active Monolayers Self-Assembled on Gold Electrodes—Effect of Their Structures on Electrochemical Parameters and DNA Sensing Ability

Molecules ◽  
2020 ◽  
Vol 25 (3) ◽  
pp. 607 ◽  
Author(s):  
Kamila Malecka ◽  
Shalini Menon ◽  
Gopal Palla ◽  
Krishnapillai Girish Kumar ◽  
Mathias Daniels ◽  
...  
Keyword(s):  
Electron Transfer ◽  
Transition Metal ◽  
Redox Activity ◽  
Gold Electrodes ◽  
Complex Structures ◽  
Transfer Coefficients ◽  
Sensing Properties ◽  
Redox Active ◽  
Electrochemical Parameters ◽  
Self Assembled

The background: The monolayers self-assembled on the gold electrode incorporated transition metal complexes can act both as receptor (“host” molecules) immobilization sites, as well as transducer for interface recognitions of “guest” molecules present in the aqueous solutions. Their electrochemical parameters influencing the sensing properties strongly depend on the transition metal complex structures. The objectives: The electrochemical characterization of the symmetric terpyridine–M2+–terpyridine and asymmetric dipyrromethene–M2+–terpyridine complexes modified with ssDNA probe covalently attached to the gold electrodes and exploring their ssDNA sensing ability were the main aims of the research presented. The methods: Two transition metal cations have been selected: Cu2+ and Co2+ for creation of redox-active monolayers. The electron transfer coefficients indicating the reversibility and electron transfer rate constant measuring kinetic of redox reactions have been determined for all SAMs studied using: Cyclic Voltammetry, Osteryoung Square-Wave Voltammetry, and Differential Pulse Voltammetry. All redox-active platforms have been applied for immobilization of ssDNA probe. Next, their sensing properties towards complementary DNA target have been explored electrochemically. The results: All SAMs studied were stable displaying quasi-reversible redox activity. The linear relationships between cathodic and anodic current vs. san rate were obtained for both symmetric and asymmetric SAMs incorporating Co2+ and Cu2+, indicating that oxidized and reduced redox sites are adsorbed on the electrode surface. The ssDNA sensing ability were observed in the fM concentration range. The low responses towards non-complementary ssDNA sequences provided evidences for sensors good selectivity. The conclusions: All redox-active SAMs modified with a ssDNA probe were suitable for sensing of ssDNA target, with very good sensitivity in fM range and very good selectivity. The detection limits obtained for SAMs incorporating Cu2+, both symmetric and asymmetric, were better in comparison to SAMs incorporating Co2+. Thus, selection of the right transition metal cation has stronger influence on ssDNA sensing ability, than complex structures.

Diffusionless electron transfer of microperoxidase-11 on gold electrodes

1999 ◽  
Vol 469 (2) ◽  
pp. 123-131 ◽  
Author(s):  
Tautgirdas Ruzgas ◽  
Adolfas Gaigalas ◽  
Lo Gorton
Keyword(s):  
Electron Transfer ◽  
Gold Electrodes

Improved direct electron transfer-type bioelectrocatalysis of bilirubin oxidase using porous gold electrodes

2019 ◽  
Vol 843 ◽  
pp. 47-53 ◽  
Author(s):  
Yui Takahashi ◽  
Mizue Wanibuchi ◽  
Yuki Kitazumi ◽  
Osamu Shirai ◽  
Kenji Kano
Keyword(s):  
Electron Transfer ◽  
Direct Electron Transfer ◽  
Gold Electrodes ◽  
Bilirubin Oxidase ◽  
Porous Gold
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