scholarly journals Slow Unfolded-State Structuring in Acyl-CoA Binding Protein Folding Revealed by Simulation and Experiment

2012 ◽  
Vol 134 (30) ◽  
pp. 12565-12577 ◽  
Author(s):  
Vincent A. Voelz ◽  
Marcus Jäger ◽  
Shuhuai Yao ◽  
Yujie Chen ◽  
Li Zhu ◽  
...  
Keyword(s):  
Protein Folding ◽  
Binding Protein ◽  
Unfolded State ◽  
Simulation And Experiment

scholarly journals High stability of trehalose/maltose binding protein fromThermococcus litoralismakes it a good candidate as a sensitive element in biosensor systems for sugar control

2010 ◽  
Vol 24 (3-4) ◽  
pp. 349-353 ◽  
Author(s):  
Olga I. Povarova ◽  
Olga V. Stepanenko ◽  
Anna I. Sulatskaya ◽  
Irina M. Kuznetsova ◽  
Konstantin K. Turoverov ◽  
...  
Keyword(s):  
Free Energy ◽  
Sensitive Element ◽  
High Stability ◽  
Binding Protein ◽  
Maltose Binding Protein ◽  
Thermococcus Litoralis ◽  
Thermophilic Archaeon ◽  
Unfolded State ◽  
The Stability ◽  
Innate Ability

Fluorescence and circular dichroism in far-UV region were used to study the stability of trehalose/maltose binding protein (TMBP) from hyper thermophilic archaeonThermococcus litoralisand its complex with glucose (TMBP/Glc). The evaluation of difference between free energy of native and unfolded state for TMBP and TMBP/Glc showed that both of them are several times higher than that of proteins from mesophilic organisms. Due to the high stability and innate ability to bind glucose this protein is a good candidate as a sensitive element in biosensor systems for sugar control.

scholarly journals Unfolded-State Dynamics and Structure of Protein L Characterized by Simulation and Experiment

2010 ◽  
Vol 132 (13) ◽  
pp. 4702-4709 ◽  
Author(s):  
Vincent A. Voelz ◽  
Vijay R. Singh ◽  
William J. Wedemeyer ◽  
Lisa J. Lapidus ◽  
Vijay S. Pande
Keyword(s):  
Protein L ◽  
Unfolded State ◽  
Simulation And Experiment

scholarly journals Role of unfolded state heterogeneity and en-route ruggedness in protein folding kinetics

2006 ◽  
Vol 15 (3) ◽  
pp. 564-582 ◽  
Author(s):  
Paul A. Ellison ◽  
Silvia Cavagnero
Keyword(s):  
Protein Folding ◽  
Folding Kinetics ◽  
Unfolded State
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