Rigid P-Chiral Phosphine Ligands with tert-Butylmethylphosphino Groups for Rhodium-Catalyzed Asymmetric Hydrogenation of Functionalized Alkenes

2012 ◽  
Vol 134 (3) ◽  
pp. 1754-1769 ◽  
Author(s):  
Tsuneo Imamoto ◽  
Ken Tamura ◽  
Zhenfeng Zhang ◽  
Yumi Horiuchi ◽  
Masashi Sugiya ◽  
...  
Keyword(s):  
Asymmetric Hydrogenation ◽  
Phosphine Ligands ◽  
Chiral Phosphine Ligands

Rhodium-Catalyzed, Phosphorus(III)-Directed Hydroarylation of Internal Alkynes: Facile and Efficient Access to New Phosphine Ligands

Synlett ◽  
2020 ◽  
Author(s):  
Minyan Wang ◽  
Zhuangzhi Shi ◽  
Huanhuan Luo ◽  
Dawei Wang
Keyword(s):  
High Selectivity ◽  
Enantiomeric Excess ◽  
Phosphine Ligands ◽  
Rapid Construction ◽  
Efficient Access ◽  
Internal Alkynes ◽  
Great Progress ◽  
Chiral Phosphine Ligands ◽  
Optimized Conditions ◽  
Made In

AbstractOrganophosphines are an important class of ligands widely used in organic chemistry. Although great progress has recently been made in the rapid construction of new phosphines through Rh- or Ru-catalyzed C–H bond functionalizations, synthetic access to more diverse phosphines remains a challenge. We describe an efficient process for the rhodium-catalyzed phosphorus(III)-directed hydroarylation of internal alkynes to generate various alkenylated and 2′,6′-dialkenylated biarylphosphines with high selectivity. A range of diverse alkynes and phosphines were effectively prepared with broad functional-group compatibility under the optimized conditions. In addition, the developed protocol can be extended to modify chiral phosphine ligands, providing enantioenriched alkenylated phosphines without erosion of the enantiomeric excess.

ChemInform Abstract: Palladium-Catalyzed Asymmetric Allylic Alkylation of Indoles by C-N Bond Axially Chiral Phosphine Ligands.

ChemInform ◽  
2013 ◽  
Vol 44 (41) ◽  
pp. no-no
Author(s):  
Takashi Mino ◽  
Miho Ishikawa ◽  
Kenji Nishikawa ◽  
Kazuya Wakui ◽  
Masami Sakamoto
Keyword(s):  
Phosphine Ligands ◽  
Allylic Alkylation ◽  
Asymmetric Allylic Alkylation ◽  
Axially Chiral ◽  
Chiral Phosphine Ligands ◽  
Palladium Catalyzed

Chiral Phosphine Ligands with Amino Acid Moieties

1999 ◽  
Vol 147 (1) ◽  
pp. 393-393
Author(s):  
Michael Tepper ◽  
Othmar Stelzer ◽  
Thomas Häusler ◽  
William S. Sheldrick
Keyword(s):  
Amino Acid ◽  
Phosphine Ligands ◽  
Chiral Phosphine Ligands

ChemInform Abstract: Iridium Catalysts with Chiral Imidazole-Phosphine Ligands for Asymmetric Hydrogenation of Vinyl Fluorides and other Olefins.

ChemInform ◽  
2008 ◽  
Vol 39 (39) ◽  
Author(s):  
Paeivi Kaukoranta ◽  
Mattias Engman ◽  
Christian Hedberg ◽  
Jonas Bergquist ◽  
Pher G. Andersson
Keyword(s):  
Asymmetric Hydrogenation ◽  
Phosphine Ligands ◽  
Iridium Catalysts ◽  
Vinyl Fluorides

The combinatorial synthesis of chiral phosphine ligands

1996 ◽  
Vol 37 (36) ◽  
pp. 6475-6478 ◽  
Author(s):  
Scott R. Gilbertson ◽  
Xifang Wang
Keyword(s):  
Phosphine Ligands ◽  
Combinatorial Synthesis ◽  
Chiral Phosphine Ligands
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