Organocatalytic Asymmetric Biomimetic Transamination: From α-Keto Esters to Optically Active α-Amino Acid Derivatives

Xiao Xiao; Ying Xie; Cunxiang Su; Mao Liu; Yian Shi

doi:10.1021/ja203138q

Organocatalytic Asymmetric Biomimetic Transamination: From α-Keto Esters to Optically Active α-Amino Acid Derivatives

Journal of the American Chemical Society ◽

10.1021/ja203138q ◽

2011 ◽

Vol 133 (33) ◽

pp. 12914-12917 ◽

Cited By ~ 95

Author(s):

Xiao Xiao ◽

Ying Xie ◽

Cunxiang Su ◽

Mao Liu ◽

Yian Shi

Keyword(s):

Amino Acid ◽

Optically Active ◽

Amino Acid Derivatives ◽

Keto Esters

Download Full-text

Catalytic Asymmetric Mono-Fluorination of α-Keto Esters: Synthesis of Optically Active β-Fluoro-α-Hydroxy and β-Fluoro-α-Amino Acid Derivatives

Angewandte Chemie ◽

10.1002/ange.201201303 ◽

2012 ◽

Vol 124 (19) ◽

pp. 4659-4663 ◽

Cited By ~ 16

Author(s):

Shoko Suzuki ◽

Yuki Kitamura ◽

Sylvain Lectard ◽

Yoshitaka Hamashima ◽

Mikiko Sodeoka

Keyword(s):

Amino Acid ◽

Optically Active ◽

Amino Acid Derivatives ◽

Keto Esters ◽

Catalytic Asymmetric

Download Full-text

ChemInform Abstract: Catalytic Asymmetric Monofluorination of α-Keto Esters: Synthesis of Optically Active β-Fluoro-α-hydroxy and β-Fluoro-α-amino Acid Derivatives.

ChemInform ◽

10.1002/chin.201238023 ◽

2012 ◽

Vol 43 (38) ◽

pp. no-no

Author(s):

Shoko Suzuki ◽

Yuki Kitamura ◽

Sylvain Lectard ◽

Yoshitaka Hamashima ◽

Mikiko Sodeoka

Keyword(s):

Amino Acid ◽

Optically Active ◽

Amino Acid Derivatives ◽

Keto Esters ◽

Catalytic Asymmetric

Download Full-text

ChemInform Abstract: Organocatalytic Asymmetric Biomimetic Transamination: From α-Keto Esters to Optically Active α-Amino Acid Derivatives.

ChemInform ◽

10.1002/chin.201204023 ◽

2011 ◽

Vol 43 (4) ◽

pp. no-no

Author(s):

Xiao Xiao ◽

Ying Xie ◽

Cunxiang Su ◽

Mao Liu ◽

Yian Shi

Keyword(s):

Amino Acid ◽

Optically Active ◽

Amino Acid Derivatives ◽

Keto Esters

Download Full-text

Catalytic Asymmetric Mono-Fluorination of α-Keto Esters: Synthesis of Optically Active β-Fluoro-α-Hydroxy and β-Fluoro-α-Amino Acid Derivatives

Angewandte Chemie International Edition ◽

10.1002/anie.201201303 ◽

2012 ◽

Vol 51 (19) ◽

pp. 4581-4585 ◽

Cited By ~ 60

Author(s):

Shoko Suzuki ◽

Yuki Kitamura ◽

Sylvain Lectard ◽

Yoshitaka Hamashima ◽

Mikiko Sodeoka

Keyword(s):

Amino Acid ◽

Optically Active ◽

Amino Acid Derivatives ◽

Keto Esters ◽

Catalytic Asymmetric

Download Full-text

Enantioselective synthesis of optically active cis-β-thio-α-amino acid derivatives through an organocatalytic cascade thio-Michael/ring opening process

Chemical Communications ◽

10.1039/c2cc30799e ◽

2012 ◽

Vol 48 (39) ◽

pp. 4713 ◽

Cited By ~ 22

Author(s):

Zhi-Cong Geng ◽

Ning Li ◽

Jian Chen ◽

Xiao-Fei Huang ◽

Bin Wu ◽

...

Keyword(s):

Amino Acid ◽

Ring Opening ◽

Optically Active ◽

Enantioselective Synthesis ◽

Amino Acid Derivatives ◽

Opening Process

Download Full-text

Synthesis of Optically Active 2,3-Disubstituted Indoline Derivatives through Cycloaddition Reactions between Benzynes and α,β-Unsaturated γ-Aminobutyronitriles

Synlett ◽

10.1055/s-0036-1591722 ◽

2018 ◽

Vol 29 (04) ◽

pp. 530-536 ◽

Cited By ~ 4

Author(s):

Takashi Ikawa ◽

Shuji Akai ◽

Yuta Sumii ◽

Shigeaki Masuda ◽

Ding Wang ◽

...

Keyword(s):

Amino Acid ◽

Cycloaddition Reaction ◽

Optically Active ◽

Amino Acid Derivatives ◽

Cycloaddition Reactions

We report a method for synthesizing optically active 2,3-disubstituted indolines by the cycloaddition reaction of benzynes with various 4-[(4-toluenesulfonyl)amino]-(E)-but-2-enenitriles, which are readily prepared from the corresponding l-amino acid derivatives.

Download Full-text

Direct Organocatalytic Enantioselective Mannich Reactions of Ketimines: An Approach to Optically Active Quaternaryα-Amino Acid Derivatives

Angewandte Chemie International Edition ◽

10.1002/anie.200460158 ◽

2004 ◽

Vol 43 (34) ◽

pp. 4476-4478 ◽

Cited By ~ 171

Author(s):

Wei Zhuang ◽

Steen Saaby ◽

Karl Anker Jørgensen

Keyword(s):

Amino Acid ◽

Optically Active ◽

Amino Acid Derivatives ◽

Mannich Reactions

Download Full-text

ChemInform Abstract: A Convenient Synthesis of Racemic and Optically Active 1-Aza-1,3-dienes Derived from γ-Amino Esters: Reduction to α,β-Unsaturated and Saturated γ-Amino Acid Derivatives.

ChemInform ◽

10.1002/chin.200130078 ◽

2010 ◽

Vol 32 (30) ◽

pp. no-no

Author(s):

Francisco Palacios ◽

Domitila Aparicio ◽

Jesus Garcia ◽

Encina Rodriguez ◽

Alvaro Fernandez-Acebes

Keyword(s):

Amino Acid ◽

Optically Active ◽

Amino Acid Derivatives ◽

Amino Esters ◽

Convenient Synthesis

Download Full-text

Direct Organocatalytic Enantioselective Mannich Reactions of Ketimines: An Approach to Optically Active Quaternaryα-Amino Acid Derivatives

Angewandte Chemie ◽

10.1002/ange.200460158 ◽

2004 ◽

Vol 116 (34) ◽

pp. 4576-4578 ◽

Cited By ~ 70

Author(s):

Wei Zhuang ◽

Steen Saaby ◽

Karl Anker Jørgensen

Keyword(s):

Amino Acid ◽

Optically Active ◽

Amino Acid Derivatives ◽

Mannich Reactions

Download Full-text

An asymmetric synthesis of carboxylic acid derivatives, including lactic acid and α-amino acid derivatives, from optically active 1-chlorovinyl p-tolyl sulfoxides and ester lithium enolates with creation of chirality at the α-position

Tetrahedron Asymmetry ◽

10.1016/j.tetasy.2007.07.033 ◽

2007 ◽

Vol 18 (16) ◽

pp. 1934-1947 ◽

Cited By ~ 9

Author(s):

Masahiro Kido ◽

Shimpei Sugiyama ◽

Tsuyoshi Satoh

Keyword(s):

Lactic Acid ◽

Amino Acid ◽

Carboxylic Acid ◽

Asymmetric Synthesis ◽

Optically Active ◽

Amino Acid Derivatives ◽

Lithium Enolates

Download Full-text

Organocatalytic Asymmetric Biomimetic Transamination: From α-Keto Esters to Optically Active α-Amino Acid Derivatives

Catalytic Asymmetric Mono-Fluorination of α-Keto Esters: Synthesis of Optically Active β-Fluoro-α-Hydroxy and β-Fluoro-α-Amino Acid Derivatives

ChemInform Abstract: Catalytic Asymmetric Monofluorination of α-Keto Esters: Synthesis of Optically Active β-Fluoro-α-hydroxy and β-Fluoro-α-amino Acid Derivatives.

ChemInform Abstract: Organocatalytic Asymmetric Biomimetic Transamination: From α-Keto Esters to Optically Active α-Amino Acid Derivatives.

Catalytic Asymmetric Mono-Fluorination of α-Keto Esters: Synthesis of Optically Active β-Fluoro-α-Hydroxy and β-Fluoro-α-Amino Acid Derivatives

Enantioselective synthesis of optically active cis-β-thio-α-amino acid derivatives through an organocatalytic cascade thio-Michael/ring opening process

Synthesis of Optically Active 2,3-Disubstituted Indoline ­Derivatives through Cycloaddition Reactions between Benzynes and α,β-Unsaturated γ-Aminobutyronitriles

Direct Organocatalytic Enantioselective Mannich Reactions of Ketimines: An Approach to Optically Active Quaternaryα-Amino Acid Derivatives

ChemInform Abstract: A Convenient Synthesis of Racemic and Optically Active 1-Aza-1,3-dienes Derived from γ-Amino Esters: Reduction to α,β-Unsaturated and Saturated γ-Amino Acid Derivatives.

Direct Organocatalytic Enantioselective Mannich Reactions of Ketimines: An Approach to Optically Active Quaternaryα-Amino Acid Derivatives

An asymmetric synthesis of carboxylic acid derivatives, including lactic acid and α-amino acid derivatives, from optically active 1-chlorovinyl p-tolyl sulfoxides and ester lithium enolates with creation of chirality at the α-position

Synthesis of Optically Active 2,3-Disubstituted Indoline Derivatives through Cycloaddition Reactions between Benzynes and α,β-Unsaturated γ-Aminobutyronitriles