scholarly journals Discovery of Halopyridines as Quiescent Affinity Labels: Inactivation of Dimethylarginine Dimethylaminohydrolase

2011 ◽  
Vol 133 (5) ◽  
pp. 1553-1562 ◽  
Author(s):  
Corey M. Johnson ◽  
Thomas W. Linsky ◽  
Dae-Wi Yoon ◽  
Maria D. Person ◽  
Walter Fast
Keyword(s):  
Dimethylarginine Dimethylaminohydrolase ◽  
Affinity Labels

Opium Alkaloids and Affinity Labels

1990 ◽  
Author(s):  
Sydney Archer ◽  
Jean Bidlack ◽  
G. Keith Mulhollund
Keyword(s):  
Affinity Labels ◽  
Opium Alkaloids

Synthesis of Cryptophycin Affinity Labels and Tubulin Labeling

2004 ◽  
Author(s):  
Kyounglang Yang ◽  
AGunda I. Georg
Keyword(s):  
Affinity Labels

Synthesis of Cryptophycin Affinity Labels and Tubulin Labeling

2005 ◽  
Author(s):  
KyoungLang Yang ◽  
Gunda I. Georg
Keyword(s):  
Affinity Labels

The melanocyte stimulating activity of N-nitroso-2-chloroethyl-carbamoyl derivatives of α-melanotropin fragments

1988 ◽  
Vol 53 (11) ◽  
pp. 2574-2582 ◽  
Author(s):  
Hedvig Medzihradszky-Schweiger ◽  
Helga Süli-Vargha ◽  
József Bódi ◽  
Kálmán Medzihradszky
Keyword(s):  
Biological Activity ◽  
Active Site ◽  
Frog Skin ◽  
Terminal Sequence ◽  
Subsequent Reaction ◽  
Affinity Labels ◽  
Derivatives Of

A number of N-nitroso-2-chloroethyl-carbamoyl (Q(NO)) derivatives of α-melanotropin fragments have been synthesized and their effect on the frog skin melanocytes studied. Peptides substituted in this way possess the biological activity of the parent compounds, indicating that they preserved their receptor recognizing ability. These compounds can therefore serve as affinity labels. Some of these derivatives, related to the C-terminal sequence of α-melanotropin show prolonged darkening reaction, which does not influence the subsequent reaction of melanocytes with α-melanotropin. The Q(NO)-derivative of a fragment derived from the classical active site of the hormone shows, however, inhibition of the effect of α-melanotropin. It can be concluded that the latter peptide acts through the melanotropin receptor, while others, related to the C-terminal sequence of the hormone through another mechanism.

scholarly journals A new key player in VEGF-dependent angiogenesis in human hepatocellular carcinoma: dimethylarginine dimethylaminohydrolase 1

Angiogenesis ◽  
2017 ◽  
Vol 20 (4) ◽  
pp. 557-565 ◽  
Author(s):  
Nikki Buijs ◽  
J. Efraim Oosterink ◽  
Morgan Jessup ◽  
Henk Schierbeek ◽  
Donna B. Stolz ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Human Hepatocellular Carcinoma ◽  
Dimethylarginine Dimethylaminohydrolase

scholarly journals Metal-Conjugated Affinity Labels: A New Concept to Create Enantioselective Artificial Metalloenzymes

ChemistryOpen ◽  
2013 ◽  
Vol 2 (2) ◽  
pp. 50-54 ◽  
Author(s):  
Thomas Reiner ◽  
Dominik Jantke ◽  
Alexander N. Marziale ◽  
Andreas Raba ◽  
Jörg Eppinger
Keyword(s):  
Affinity Labels ◽  
Artificial Metalloenzymes
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