Regioselective C−H Activation and Sequential C−C and C−O Bond Formation Reactions of Aryl Ketones Promoted by an Yttrium Carbene

2010 ◽  
Vol 132 (41) ◽  
pp. 14379-14381 ◽  
Author(s):  
David P. Mills ◽  
Lyndsay Soutar ◽  
William Lewis ◽  
Alexander J. Blake ◽  
Stephen T. Liddle
Keyword(s):  
Bond Formation ◽  
Aryl Ketones ◽  
Bond Formation Reactions

Recent Advances on C-Se Bond-forming Reactions at Low and Room Temperature

2020 ◽  
Vol 23 (28) ◽  
pp. 3206-3225 ◽  
Author(s):  
Amol D. Sonawane ◽  
Mamoru Koketsu
Keyword(s):  
Room Temperature ◽  
Bond Formation ◽  
Bond Forming ◽  
Material Chemistry ◽  
Recent Advances ◽  
Bond Forming Reactions ◽  
Bond Formation Reactions

: Over the last decades, many methods have been reported for the synthesis of selenium- heterocyclic scaffolds because of their interesting reactivities and applications in the medicinal as well as in the material chemistry. This review describes the recent numerous useful methodologies on C-Se bond formation reactions which were basically carried out at low and room temperature.

Synthesis of Drugs and Biorelevant N-heterocycles Employing Recent Advances in C-N Bond Formation

2020 ◽  
Vol 24 (20) ◽  
pp. 2293-2340
Author(s):  
Firdoos Ahmad Sofi ◽  
Prasad V. Bharatam
Keyword(s):  
Kinase Inhibitors ◽  
Bond Formation ◽  
Comprehensive Review ◽  
Biologically Relevant ◽  
Lead Compounds ◽  
Heterocyclic Molecules ◽  
The Past ◽  
Anti Cancer ◽  
Modern Methods ◽  
Bond Formation Reactions

C-N bond formation is a particularly important step in the generation of many biologically relevant heterocyclic molecules. Several methods have been reported for this purpose over the past few decades. Well-known named reactions like Ullmann-Goldberg coupling, Buchwald-Hartwig coupling and Chan-Lam coupling are associated with the C-N bond formation reactions. Several reviews covering this topic have already been published. However, no comprehensive review covering the synthesis of drugs/ lead compounds using the C-N bond formation reactions was reported. In this review, we cover many modern methods of the C-N bond formation reactions, with special emphasis on metal-free and green chemistry methods. We also report specific strategies adopted for the synthesis of drugs, which involve the C-N bond formation reactions. Examples include anti-cancer, antidepressant, anti-inflammatory, anti-atherosclerotic, anti-histaminic, antibiotics, antibacterial, anti-rheumatic, antiepileptic and anti-diabetic agents. Many recently developed lead compounds generated using the C-N bond formation reactions are also covered in this review. Examples include MAP kinase inhibitors, TRKs inhibitors, Polo-like Kinase inhibitors and MPS1 inhibitors.

Oxidative Aromatic C−O Bond Formation: Synthesis of 3-Functionalized Benzo[b]furans by FeCl3-Mediated Ring Closure of α-Aryl Ketones

2009 ◽  
Vol 11 (21) ◽  
pp. 4978-4981 ◽  
Author(s):  
Zhidan Liang ◽  
Weizhe Hou ◽  
Yunfei Du ◽  
Yongliang Zhang ◽  
Yan Pan ◽  
...  
Keyword(s):  
Bond Formation ◽  
Ring Closure ◽  
Aryl Ketones

Bismuth(iii)dichalcogenones as highly active catalysts in multiple C–C bond formation reactions

2016 ◽  
Vol 45 (12) ◽  
pp. 5196-5209 ◽  
Author(s):  
Katam Srinivas ◽  
Arruri Sathyanarayana ◽  
Chatla Naga Babu ◽  
Ganesan Prabusankar
Keyword(s):  
Bond Formation ◽  
Structural Motifs ◽  
Highly Active ◽  
Bond Formation Reactions

Thirteen new bismuth(iii) dichalcogenone derivatives with diversified structural motifs were successfully isolated and used as potential catalysts for the synthesis of triaryl- or triheteroarylmethanes.

Zirconium Catalyzed or Mediated Regioselective C–C Bond Formation Reactions of α,β-Unsaturated Acetals

1994 ◽  
Vol 23 (2) ◽  
pp. 259-262 ◽  
Author(s):  
Tamotsu Takahashi ◽  
Denis Y. Kondakov ◽  
Noriyuki Suzuki
Keyword(s):  
Bond Formation ◽  
Bond Formation Reactions
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