scholarly journals Understanding the Effect of Magnesium Ion Concentration on the Catalytic Activity of Ribonuclease H through Computation: Does a Third Metal Binding Site Modulate Endonuclease Catalysis?

2010 ◽  
Vol 132 (39) ◽  
pp. 13702-13712 ◽  
Author(s):  
Ming-Hsun Ho ◽  
Marco De Vivo ◽  
Matteo Dal Peraro ◽  
Michael L. Klein
Keyword(s):  
Catalytic Activity ◽  
Binding Site ◽  
Metal Binding ◽  
Ion Concentration ◽  
Ribonuclease H ◽  
Magnesium Ion ◽  
Metal Binding Site

scholarly journals Enzyme repurposing of a hydrolase as an emergent peroxidase upon metal binding

2015 ◽  
Vol 6 (7) ◽  
pp. 4060-4065 ◽  
Author(s):  
Nobutaka Fujieda ◽  
Jonas Schätti ◽  
Edward Stuttfeld ◽  
Kei Ohkubo ◽  
Timm Maier ◽  
...  
Keyword(s):  
Catalytic Activity ◽  
Binding Site ◽  
Metal Binding ◽  
Metal Binding Site ◽  
Metal Cofactor

Adding a metal cofactor to a protein bearing a latent metal binding site endows the macromolecule with nascent catalytic activity.

Unraveling the Substrate−Metal Binding Site of Ferrochelatase:  An X-ray Absorption Spectroscopic Study†

Biochemistry ◽  
2002 ◽  
Vol 41 (15) ◽  
pp. 4809-4818 ◽  
Author(s):  
Gloria C. Ferreira ◽  
Ricardo Franco ◽  
Arianna Mangravita ◽  
Graham N. George
Keyword(s):  
Spectroscopic Study ◽  
Binding Site ◽  
Metal Binding ◽  
Metal Binding Site ◽  
X Ray ◽  
Substrate Metal ◽  
X Ray Absorption

Construction of an additional metal-binding site in human metallothionein-2

2006 ◽  
Vol 101 (4) ◽  
pp. 354-360 ◽  
Author(s):  
Mitsutoshi Toyama ◽  
Mariko Sasaki ◽  
Noriaki Hirayama ◽  
Yoshikatsu Murooka ◽  
Mitsuo Yamashita
Keyword(s):  
Binding Site ◽  
Metal Binding ◽  
Metal Binding Site
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