DNA-Directed Synthesis of Aniline and 4-Aminobiphenyl Oligomers:  Programmed Transfer of Sequence Information to a Conjoined Polymer Nanowire

2008 ◽  
Vol 130 (10) ◽  
pp. 2965-2973 ◽  
Author(s):  
Bhaskar Datta ◽  
Gary B. Schuster
Keyword(s):  
Sequence Information ◽  
Directed Synthesis

scholarly journals Sequence information transfer using covalent template-directed synthesis

2019 ◽  
Vol 10 (20) ◽  
pp. 5258-5266 ◽  
Author(s):  
Diego Núñez-Villanueva ◽  
Maria Ciaccia ◽  
Giulia Iadevaia ◽  
Elena Sanna ◽  
Christopher A. Hunter
Keyword(s):  
Information Transfer ◽  
Sequence Information ◽  
Polymer Product ◽  
Directed Synthesis

Kinetically inert ester bonds were used to attach monomers to a template, dictating the sequence of the polymer product.

Perception of Sequence Information

2005 ◽  
Author(s):  
An Oskarsson ◽  
Reid Hastie ◽  
Gary H. McClelland ◽  
Leaf Van Boven
Keyword(s):  
Sequence Information

Drawing enhances item information but undermines sequence information in memory.

2019 ◽  
Vol 45 (4) ◽  
pp. 689-699 ◽  
Author(s):  
Tanya R. Jonker ◽  
Jeffrey D. Wammes ◽  
Colin M. MacLeod
Keyword(s):  
Item Information ◽  
Sequence Information

Personality Genetics

2018 ◽  
Author(s):  
Jaime Derringer
Keyword(s):  
Cultural Context ◽  
Behavior Genetics ◽  
Genetic Research ◽  
Reliability And Validity ◽  
Experimental Manipulation ◽  
Sequence Information ◽  
Natural Experiments ◽  
Genetic Sequence ◽  
Form And Function ◽  
Causal Pathway

Although correlations between personality and health are consistently observed, often the causal pathway, or even the direction of effect, is unknown. Genes provide an additional node of information which may be included to help clarify the relationship between personality and health. Genetically informative studies, whether focused on family-identified relationships or specific genotypes, provide clear benefits to disentangling causal processes. Genetic measures approach near universal reliability and validity: processes of inheritance are consistent across cultures, geography, and time, such that similar models and instruments may be applied to incredibly diverse populations. Although frequency and intercorrelations differ by ancestry background (Novembre et al., 2008) and cultural context (Tucker-Drob & Bates, 2016) may exert powerful moderating effects, fundamental form and function is consistent across all members of our species, and even many other species. Genetic sequence information is also of course highly temporally stable, and possesses temporal precedence. That is, the literal genetic sequence is lifetime-stable and comes before all other experiences. Human behavior genetic research, like most personality research, faces limitations in terms of causal inferences that may be made in the absence of experimental manipulation. But behavior genetics takes advantage of natural experiments: populations that differ in terms of genetic similarity (either inferred – such as twins – or measured – such as genotyping methods) to begin to unravel the complex influences on individual differences in personality and health outcomes.

AFLP-derived, Codominant Markers for Locus-specific Applications

HortScience ◽  
1998 ◽  
Vol 33 (3) ◽  
pp. 514e-514
Author(s):  
James M. Bradeen ◽  
Philipp W. Simon
Keyword(s):  
Linkage Mapping ◽  
Large Scale ◽  
Pcr Primers ◽  
Inverse Pcr ◽  
Sequence Information ◽  
Pcr Assay ◽  
Specific Primers ◽  
Simultaneous Evaluation ◽  
Feral Populations ◽  
Diversity Assessment

The amplified fragment length polymorphism (AFLP) is a powerful marker, allowing rapid and simultaneous evaluation of multiple potentially polymorphic sites. Although well-adapted to linkage mapping and diversity assessment, AFLPs are primarily dominant in nature. Dominance, relatively high cost, and technological difficulty limit use of AFLPs for marker-aided selection and other locus-specific applications. In carrot the Y2 locus conditions carotene accumulation in the root xylem. We identified AFLP fragments linked to the dominant Y2 allele and pursued conversion of those fragments to codominant, PCR-based forms useful for locus-specific applications. The short length of AFLPs (≈60 to 500 bp) precludes development of longer, more specific primers as in SCAR development. Instead, using sequence information from cloned AFLP fragments for primer design, regions outside of the original fragment were amplified by inverse PCR or ligation-mediated PCR, cloned, and sequenced. Differences in sequences associated with Y2 vs. y2 allowed development of simple PCR assays differentiating those alleles. PCR primers flanking an insertion associated with the recessive allele amplified differently sized products for the two Y2 alleles in one assay. This assay is rapid, technologically simple (requiring no radioactivity and little advanced training or equipment), reliable, inexpensive, and codominant. Our PCR assay has a variety of large scale, locus-specific applications including genotyping diverse carrot cultivars and wild and feral populations. Efforts are underway to improve upon conversion technology and to more extensively test the techniques we have developed.

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