Chiral Separation:  Mechanism Modeling in Two-Dimensional Systems

2007 ◽  
Vol 129 (12) ◽  
pp. 3545-3555 ◽  
Author(s):  
Irina Paci ◽  
Igal Szleifer ◽  
Mark A. Ratner
Keyword(s):  
Chiral Separation ◽  
Separation Mechanism ◽  
Two Dimensional ◽  
Mechanism Modeling

Separation of a boundary jet in a rotating fluid

1990 ◽  
Vol 217 ◽  
pp. 41-69 ◽  
Author(s):  
Melvin E. Stern ◽  
J. A. Whitehead
Keyword(s):  
Laboratory Experiment ◽  
Vertical Wall ◽  
Cumulative Effect ◽  
Obtuse Angle ◽  
Jet Flows ◽  
Separation Mechanism ◽  
Two Dimensional ◽  
Rotating Fluid ◽  
Separation Effect ◽  
Viscous Forces

A semi-infinite jet flows along a vertical wall in a rotating fluid, with the nose of the intrusion approaching a corner where the wall turns through an obtuse angle θ + 180°. The jet separates at the corner and flows into the interior if θ exceeds a critical θc, otherwise part of the jet continues around the corner and flows along the downstream segment of the wall. The separation criterion is computed using an inviscid and piecewise-uniform-vorticity model, with s denoting the ratio of the maximum ‘offshore’ to ‘inshore’ vorticity. The separation effect is demonstrated by a laboratory experiment in which a two-dimensional jet flows along the wall from a source. Average velocities are used to estimate s, and to make semi-quantitative comparisons of experimental and theoretical θc. This suggests that the separation mechanism is independent of local viscous forces, although the cumulative effect of lateral eddy stresses in the jet is important in establishing the value of s immediately upstream from the corner. We suggest that our barotropic separation mechanism is relevant to mesoscale oceanic coastal currents.

Chiral separation of β-blockers by MEEKC using neutral microemulsion: Analysis of separation mechanism and further elucidation of resolution equation

2012 ◽  
Vol 34 (2) ◽  
pp. 260-268 ◽  
Author(s):  
Shao-Qiang Hu ◽  
Wen-Juan Lü ◽  
Yan-Hua Ma ◽  
Qin Hu ◽  
Li-Jun Dong ◽  
...  
Keyword(s):  
Chiral Separation ◽  
Separation Mechanism ◽  
Résolution Équation ◽  
Β Blockers

scholarly journals On Separation Mechanism of Two-Dimensional Cascade Impactor

1969 ◽  
Vol 33 (12) ◽  
pp. 1265-1271,a1 ◽  
Author(s):  
Shinichi Yuu ◽  
Koichi Iinoya
Keyword(s):  
Cascade Impactor ◽  
Separation Mechanism ◽  
Two Dimensional

scholarly journals Isotopic separation of helium through graphyne membranes: A ring polymer molecular dynamics study

2021 ◽  
Author(s):  
Somnath Bhowmick ◽  
Marta Isabel Hernández ◽  
José Campos-Martínez ◽  
Yury V. Suleimanov
Keyword(s):  
Molecular Dynamics ◽  
Microscopic Level ◽  
Active Area ◽  
Separation Mechanism ◽  
Two Dimensional ◽  
Technological Processes ◽  
Ring Polymer ◽  
Isotopic Separation ◽  
Ring Polymer Molecular Dynamics

Microscopic-level understanding of the separation mechanism for two-dimensional (2D) membranes is an active area of research due to potential implications of this class of membranes for various technological processes. Helium...

Chiral Separation of Oxomemazine Enantiomers by HPLC Technique and Enantiomeric Separation Mechanism via Docking Studies

2019 ◽  
Vol 16 ◽  
Author(s):  
Prachi Raikar ◽  
B. M. Gurupadayya ◽  
Subhankar P. Mandal ◽  
R Maruthi ◽  
Prabitha Prabhakar
Keyword(s):  
Chiral Separation ◽  
High Performance ◽  
Docking Simulation ◽  
Enantiomeric Separation ◽  
High Performance Liquid Chromatographic ◽  
Docking Studies ◽  
Hplc Method ◽  
Separation Mechanism ◽  
Ich Guidelines ◽  
Liquid Chromatographic

Background: A normal phase- High Performance Liquid Chromatographic (HPLC) method was developed for the enantioseparation of Oxomemazine. Method: Separation of enantiomers was attained on Amylose Tris (5-chloro-2-methylphenylcarbamate) using n-hexane: Iso-propyl Alcohol (IPA): Diethylamine (DEA) (60: 40: 0.1) as the mobile phase and the peaks were observed at 227nm using PDA detector. The run time of the analysis was set to 30 min. Results: Linearity was found in the range 10-50 µgmL-1. The enantiomers were separated at retention times 16.87 min and 21.37 min. Conclusion: The developed method was validated as per the ICH guidelines, thus proving the method to be selective, precise and showing linear response of Oxomemazine peak areas. Additionally, the method of chiral separation being understood by docking simulation study. The method was appropriate for analysis of Oxomemazine in the pure form and its formulation.

DNA Electrophoresis on Two-dimensional Arrays of SiO2 Beads

2000 ◽  
Vol 636 ◽  
Author(s):  
Young-Soo Seo ◽  
V.A. Samuilov ◽  
J. Sokolov ◽  
M. Rafailovich ◽  
D. Gersappe ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Surface Friction ◽  
Separation Mechanism ◽  
Two Dimensional ◽  
Langmuir Blodgett ◽  
Silica Bead ◽  
Corrugated Surfaces ◽  
Novel Approach ◽  
Separation Media ◽  
Si Wafer

AbstractA novel approach of fabricating 2-D arrays of SiO2 beads on a Si surface using the Langmuir-Blodgett (LB) technique is reported. The corrugated surfaces were tested as a separation media for surface electrophoresis of DNA molecules. The measured electrophoretic mobility for λ-DNA is only 20% slower than previously measured on a flat Si wafer. This indicates that the separation mechanism is due to surface friction rather than biased reptation as reported by Tinland in the three dimensional Silica bead matrix where the mobility is two orders of magnitude smaller.

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