Catalytic Asymmetric Reductive Amination of Aldehydes via Dynamic Kinetic Resolution

2006 ◽  
Vol 128 (40) ◽  
pp. 13074-13075 ◽  
Author(s):  
Sebastian Hoffmann ◽  
Marcello Nicoletti ◽  
Benjamin List
Keyword(s):  
Reductive Amination ◽  
Kinetic Resolution ◽  
Dynamic Kinetic Resolution ◽  
Catalytic Asymmetric

scholarly journals Catalytic Asymmetric Reductive Amination of Aldehydes via Dynamic Kinetic Resolution.

ChemInform ◽  
2007 ◽  
Vol 38 (6) ◽  
Author(s):  
Sebastian Hoffmann ◽  
Marcello Nicoletti ◽  
Benjamin List
Keyword(s):  
Reductive Amination ◽  
Kinetic Resolution ◽  
Dynamic Kinetic Resolution ◽  
Catalytic Asymmetric

Asymmetric Synthesis of a Key Intermediate for Tofacitinib via a Dynamic Kinetic Resolution-Reductive Amination Protocol

2018 ◽  
Vol 22 (12) ◽  
pp. 1817-1822 ◽  
Author(s):  
Gerard K. M. Verzijl ◽  
Christian Schuster ◽  
Thomas Dax ◽  
André H. M. de Vries ◽  
Laurent Lefort
Keyword(s):  
Asymmetric Synthesis ◽  
Reductive Amination ◽  
Kinetic Resolution ◽  
Dynamic Kinetic Resolution

Dynamic Kinetic Resolution for the Catalytic Asymmetric Total Synthesis of Antithrombotic Agents M58163 and M58169

2007 ◽  
Vol 349 (4-5) ◽  
pp. 617-628 ◽  
Author(s):  
Fumihiko Saitoh ◽  
Hidemitsu Nishida ◽  
Takafumi Mukaihira ◽  
Kohsuke Aikawa ◽  
Koichi Mikami
Keyword(s):  
Total Synthesis ◽  
Kinetic Resolution ◽  
Dynamic Kinetic Resolution ◽  
Antithrombotic Agents ◽  
Asymmetric Total Synthesis ◽  
Catalytic Asymmetric

Dynamic Kinetic Resolution in Enantioselective Reductive Amination ofα-Branched Aldehydes by Lewis Base Organocatalyzed Hydrosilylation

2017 ◽  
Vol 2 (14) ◽  
pp. 4076-4078 ◽  
Author(s):  
Fang-Zhi Hu ◽  
Hui Chen ◽  
Xiao-Ying Xu ◽  
Wei-Cheng Yuan ◽  
Xiao-Mei Zhang
Keyword(s):  
Reductive Amination ◽  
Kinetic Resolution ◽  
Lewis Base ◽  
Dynamic Kinetic Resolution

Catalytic asymmetric transfer hydrogenation/dynamic kinetic resolution: an efficient synthesis of florfenicol

Tetrahedron ◽  
2016 ◽  
Vol 72 (14) ◽  
pp. 1787-1793 ◽  
Author(s):  
Xinlong Wang ◽  
Lingjun Xu ◽  
Lingjie Yan ◽  
Haifeng Wang ◽  
Sheng Han ◽  
...  
Keyword(s):  
Kinetic Resolution ◽  
Transfer Hydrogenation ◽  
Efficient Synthesis ◽  
Asymmetric Transfer Hydrogenation ◽  
Dynamic Kinetic Resolution ◽  
Catalytic Asymmetric

Rhodium-Catalyzed anti and syn Enantio- and Diastereoselective Transfer Hydrogenation of α-Amino β-Keto Ester Hydrochlorides through Dynamic Kinetic Resolution

Synthesis ◽  
2016 ◽  
Vol 48 (19) ◽  
pp. 3357-3363 ◽  
Author(s):  
Quentin Llopis ◽  
Charlène Férard ◽  
Gérard Guillamot ◽  
Phannarath Phansavath ◽  
Virginie Ratovelomanana-Vidal
Keyword(s):  
Formic Acid ◽  
Kinetic Resolution ◽  
Amino Alcohols ◽  
Hydrogen Donor ◽  
Transfer Hydrogenation ◽  
Asymmetric Transfer Hydrogenation ◽  
Dynamic Kinetic Resolution ◽  
Keto Ester ◽  
Catalytic Asymmetric ◽  
Donor Source

A mild catalytic asymmetric transfer hydrogenation of a series of α-amino β-keto ester hydrochlorides catalyzed by a rhodium(III) complex is reported. The use of the formic acid/triethylamine system as the hydrogen donor source provided the corresponding anti and syn amino alcohols with complete conversions, fair diastereoselectivities (up to 97:3 dr), and high enantioselectivities (ee up to >99%).

Synthesis of chiral sultams with two adjacent stereocenters via palladium-catalyzed dynamic kinetic resolution

2018 ◽  
Vol 5 (7) ◽  
pp. 1113-1117 ◽  
Author(s):  
Bo Song ◽  
Mu-Wang Chen ◽  
Yong-Gui Zhou
Keyword(s):  
Reductive Amination ◽  
Kinetic Resolution ◽  
Dynamic Kinetic Resolution ◽  
Stereogenic Centers ◽  
Palladium Catalyzed

A palladium-catalyzed intramolecular asymmetric reductive amination of racemic α-branched ketones bearing the poorly nucleophilic sulfonamides has been successfully developed through dynamic kinetic resolution, providing chiral δ-sultams with two contiguous stereogenic centers.

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