Study of Molecular Junctions with a Combined Surface-Enhanced Raman and Mechanically Controllable Break Junction Method

2006 ◽  
Vol 128 (46) ◽  
pp. 14748-14749 ◽  
Author(s):  
Jing-Hua Tian ◽  
Bo Liu ◽  
Li ◽  
Zhi-Lin Yang ◽  
Bin Ren ◽  
...  
RSC Advances ◽  
2015 ◽  
Vol 5 (69) ◽  
pp. 55720-55726
Author(s):  
Shuangshuang Li ◽  
Qun Zhou ◽  
Wenya Chu ◽  
Wei Zhao ◽  
Junwei Zheng

Effect of microenvironments on molecular junctions can be elucidated by variation in surface-enhanced Raman scattering of 4-aminothiophenol interconnected in silver/4-aminothiophenol/silver junctions modified with different molecules.


2017 ◽  
Author(s):  
Caitlin S. DeJong ◽  
David I. Wang ◽  
Aleksandr Polyakov ◽  
Anita Rogacs ◽  
Steven J. Simske ◽  
...  

Through the direct detection of bacterial volatile organic compounds (VOCs), via surface enhanced Raman spectroscopy (SERS), we report here a reconfigurable assay for the identification and monitoring of bacteria. We demonstrate differentiation between highly clinically relevant organisms: <i>Escherichia coli</i>, <i>Enterobacter cloacae</i>, and <i>Serratia marcescens</i>. This is the first differentiation of bacteria via SERS of bacterial VOC signatures. The assay also detected as few as 10 CFU/ml of <i>E. coli</i> in under 12 hrs, and detected <i>E. coli</i> from whole human blood and human urine in 16 hrs at clinically relevant concentrations of 10<sup>3</sup> CFU/ml and 10<sup>4</sup> CFU/ml, respectively. In addition, the recent emergence of portable Raman spectrometers uniquely allows SERS to bring VOC detection to point-of-care settings for diagnosing bacterial infections.


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