A High-Throughput, High-Resolution Strategy for the Study of Site-Selective DNA Binding Agents:  Analysis of a “Highly Twisted” Benzimidazole-Diamidine

Kristie D. Goodwin; Mark A. Lewis; Farial A. Tanious; Richard R. Tidwell; W. David Wilson; Millie M. Georgiadis; Eric C. Long

doi:10.1021/ja0600936

A High-Throughput, High-Resolution Strategy for the Study of Site-Selective DNA Binding Agents: Analysis of a “Highly Twisted” Benzimidazole-Diamidine

Journal of the American Chemical Society ◽

10.1021/ja0600936 ◽

2006 ◽

Vol 128 (24) ◽

pp. 7846-7854 ◽

Cited By ~ 27

Author(s):

Kristie D. Goodwin ◽

Mark A. Lewis ◽

Farial A. Tanious ◽

Richard R. Tidwell ◽

W. David Wilson ◽

...

Keyword(s):

High Resolution ◽

Dna Binding ◽

High Throughput ◽

Binding Agents ◽

Dna Binding Agents ◽

Resolution Strategy ◽

Selective Dna Binding ◽

Site Selective

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Total Synthesis of Distamycin A and 2640 Analogues: A Solution-Phase Combinatorial Approach to the Discovery of New, Bioactive DNA Binding Agents and Development of a Rapid, High-Throughput Screen for Determining Relative DNA Binding Affinity or DNA Binding Sequence Selectivity

Journal of the American Chemical Society ◽

10.1021/ja994192d ◽

2000 ◽

Vol 122 (27) ◽

pp. 6382-6394 ◽

Cited By ~ 146

Author(s):

Dale L. Boger ◽

Brian E. Fink ◽

Michael P. Hedrick

Keyword(s):

Dna Binding ◽

Total Synthesis ◽

High Throughput ◽

Solution Phase ◽

Combinatorial Approach ◽

Distamycin A ◽

Binding Agents ◽

Dna Binding Agents ◽

Dna Binding Affinity ◽

Binding Sequence

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Semi-automated high-throughput fluorescent intercalator displacement-based discovery of cytotoxic DNA binding agents from a large compound library

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2010.01.033 ◽

2010 ◽

Vol 20 (5) ◽

pp. 1685-1688 ◽

Cited By ~ 18

Author(s):

LaTeca S. Glass ◽

Aditi Bapat ◽

Mark R. Kelley ◽

Millie M. Georgiadis ◽

Eric C. Long

Keyword(s):

Dna Binding ◽

High Throughput ◽

Compound Library ◽

Binding Agents ◽

Dna Binding Agents ◽

Displacement Based ◽

Fluorescent Intercalator Displacement ◽

Large Compound

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A novel bioactive tyramine derived Schiff base and its transition metal complexes as selective DNA binding agents

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy ◽

10.1016/j.saa.2010.12.056 ◽

2011 ◽

Vol 78 (2) ◽

pp. 888-898 ◽

Cited By ~ 59

Author(s):

N. Raman ◽

S. Sobha ◽

A. Thamaraichelvan

Keyword(s):

Schiff Base ◽

Dna Binding ◽

Transition Metal ◽

Metal Complexes ◽

Transition Metal Complexes ◽

Binding Agents ◽

Dna Binding Agents ◽

Selective Dna Binding

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Pyrrolobenzodiazepines as Sequence Selective DNA Binding Agents

Medicinal Chemistry and Drug Design ◽

10.5772/38869 ◽

2012 ◽

Cited By ~ 1

Author(s):

Ahmed Kamal ◽

M. Kashi ◽

Ajay Kumar ◽

Y. V. V. Srikanth

Keyword(s):

Dna Binding ◽

Binding Agents ◽

Dna Binding Agents ◽

Selective Dna Binding

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Preface to Sequence-specific DNA Binding Agents

DNA-targeting Molecules as Therapeutic Agents - Chemical Biology ◽

10.1039/9781788012928-fp005 ◽

2018 ◽

pp. P005-P006

Keyword(s):

Dna Binding ◽

Binding Agents ◽

Dna Binding Agents

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Faculty Opinions recommendation of Total synthesis of proximicin A-C and synthesis of new furan-based DNA binding agents.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1166298.627246 ◽

2009 ◽

Author(s):

Robert Fecik

Keyword(s):

Dna Binding ◽

Total Synthesis ◽

Binding Agents ◽

Dna Binding Agents

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Binding mode and affinity studies of DNA-binding agents using topoisomerase I DNA unwinding assay

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2006.11.038 ◽

2007 ◽

Vol 17 (4) ◽

pp. 1013-1017 ◽

Cited By ~ 22

Author(s):

Ruel E. McKnight ◽

Aaron B. Gleason ◽

James A. Keyes ◽

Sadia Sahabi

Keyword(s):

Dna Binding ◽

Topoisomerase I ◽

Binding Mode ◽

Dna Unwinding ◽

Binding Agents ◽

Dna Binding Agents

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Molecular Recognition of DNA Binding Agents: High-Field 1H and 3 1P One- and Two-Dimensional NMR Studies on the 1:1 Intercalation Complexes of Mitoxantrone with Selected Oligodeoxyribonucleotides

Mechanisms of DNA Damage and Repair ◽

10.1007/978-1-4615-9462-8_22 ◽

1986 ◽

pp. 211-218

Author(s):

Albin Otter ◽

Christopher C. Hanstock ◽

George Kotovych ◽

Bernard Rayner ◽

Jacques J. Vasseur ◽

...

Keyword(s):

Dna Binding ◽

Molecular Recognition ◽

High Field ◽

Two Dimensional ◽

Nmr Studies ◽

Intercalation Complexes ◽

Binding Agents ◽

Dna Binding Agents

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Site-Selective DNA Binding Drugs

Chemistry & Biology ◽

10.1016/j.chembiol.2003.10.004 ◽

2003 ◽

Vol 10 (10) ◽

pp. 895-897 ◽

Cited By ~ 10

Author(s):

Scot W. Ebbinghaus

Keyword(s):

Dna Binding ◽

Selective Dna Binding ◽

Site Selective

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Recent Advances in Multinuclear Complexes as Potential Anticancer and DNA Binding Agents

Anti-Cancer Agents in Medicinal Chemistry ◽

10.2174/18715206113139990313 ◽

2014 ◽

Vol 14 (1) ◽

pp. 147-169 ◽

Cited By ~ 22

Author(s):

Kehua Wang ◽

Enjun Gao

Keyword(s):

Dna Binding ◽

Recent Advances ◽

Multinuclear Complexes ◽

Binding Agents ◽

Dna Binding Agents

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