Extender Unit and Acyl Carrier Protein Specificity of Ketosynthase Domains of the 6-Deoxyerythronolide B Synthase

Alice Y. Chen; Nathan A. Schnarr; Chu-Young Kim; David E. Cane; Chaitan Khosla

doi:10.1021/ja058093d

Extender Unit and Acyl Carrier Protein Specificity of Ketosynthase Domains of the 6-Deoxyerythronolide B Synthase

Journal of the American Chemical Society ◽

10.1021/ja058093d ◽

2006 ◽

Vol 128 (9) ◽

pp. 3067-3074 ◽

Cited By ~ 73

Author(s):

Alice Y. Chen ◽

Nathan A. Schnarr ◽

Chu-Young Kim ◽

David E. Cane ◽

Chaitan Khosla

Keyword(s):

Acyl Carrier Protein ◽

Carrier Protein ◽

Protein Specificity ◽

Extender Unit ◽

Deoxyerythronolide B Synthase

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Acyl-acyl carrier protein specificity of UDP-GlcNAc acyltransferases from gram-negative bacteria: relationship to lipid A structure.

Journal of Bacteriology ◽

10.1128/jb.173.11.3591-3596.1991 ◽

1991 ◽

Vol 173 (11) ◽

pp. 3591-3596 ◽

Cited By ~ 50

Author(s):

J M Williamson ◽

M S Anderson ◽

C R Raetz

Keyword(s):

Lipid A ◽

Acyl Carrier Protein ◽

Carrier Protein ◽

Gram Negative Bacteria ◽

Gram Negative ◽

Protein Specificity ◽

Lipid A Structure

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Ketosynthases in the Initiation and Elongation Modules of Aromatic Polyketide Synthases Have Orthogonal Acyl Carrier Protein Specificity†

Biochemistry ◽

10.1021/bi0341962 ◽

2003 ◽

Vol 42 (21) ◽

pp. 6588-6595 ◽

Cited By ~ 43

Author(s):

Yi Tang ◽

Taek Soon Lee ◽

Seiji Kobayashi ◽

Chaitan Khosla

Keyword(s):

Acyl Carrier Protein ◽

Polyketide Synthases ◽

Carrier Protein ◽

Protein Specificity

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Biosynthesis of Methoxymalonyl-acyl Carrier Protein (ACP) as an Extender Unit for Bafilomycin Polyketide in Streptomyces griseus DSM 2608

Biotechnology and Bioprocess Engineering ◽

10.1007/s12257-018-0427-x ◽

2018 ◽

Vol 23 (6) ◽

pp. 693-703 ◽

Cited By ~ 1

Author(s):

Nguyen Phan Kieu Hanh ◽

Jae Yoon Hwang ◽

Doo Hyun Nam

Keyword(s):

Acyl Carrier Protein ◽

Streptomyces Griseus ◽

Carrier Protein ◽

Extender Unit

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6-Deoxyerythronolide B Synthase 1 Is Specifically Acylated by a Diketide Intermediate at the β-Ketoacyl-Acyl Carrier Protein Synthase Domain of Module 2†

Biochemistry ◽

10.1021/bi961972f ◽

1996 ◽

Vol 35 (48) ◽

pp. 15244-15248 ◽

Cited By ~ 16

Author(s):

Naohiro Tsukamoto ◽

Jo-Anne Chuck ◽

Guanglin Luo ◽

Camilla M. Kao ◽

Chaitan Khosla ◽

...

Keyword(s):

Acyl Carrier Protein ◽

Carrier Protein ◽

Deoxyerythronolide B Synthase

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An acyl-carrier-protein - thioesterase domain from the 6-deoxyerythronolide B synthase of Saccharopolyspora erythraea. High-level production, purification and characterisation in Escherichia coli

European Journal of Biochemistry ◽

10.1111/j.1432-1033.1991.tb15771.x ◽

1991 ◽

Vol 195 (3) ◽

pp. 823-830 ◽

Cited By ~ 45

Author(s):

Patrick CAFFREY ◽

Brian GREEN ◽

Leonard C. PACKMAN ◽

Bernard J. RAWLINGS ◽

James STAUNTON ◽

...

Keyword(s):

Escherichia Coli ◽

Acyl Carrier Protein ◽

Saccharopolyspora Erythraea ◽

Carrier Protein ◽

High Level ◽

Deoxyerythronolide B Synthase ◽

Level Production

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Molecular recognition between ketosynthase and acyl carrier protein domains of the 6-deoxyerythronolide B synthase

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.1014081107 ◽

2010 ◽

Vol 107 (51) ◽

pp. 22066-22071 ◽

Cited By ~ 61

Author(s):

S. Kapur ◽

A. Y. Chen ◽

D. E. Cane ◽

C. Khosla

Keyword(s):

Molecular Recognition ◽

Acyl Carrier Protein ◽

Protein Domains ◽

Carrier Protein ◽

Deoxyerythronolide B Synthase

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Enzymes Involved in Fatty Acid and Polyketide Biosynthesis inStreptomyces glaucescens: Role of FabH and FabD and Their Acyl Carrier Protein Specificity†

Biochemistry ◽

10.1021/bi0258804 ◽

2002 ◽

Vol 41 (33) ◽

pp. 10462-10471 ◽

Cited By ~ 51

Author(s):

Galina Florova ◽

Galina Kazanina ◽

Kevin A. Reynolds

Keyword(s):

Fatty Acid ◽

Acyl Carrier Protein ◽

Carrier Protein ◽

Polyketide Biosynthesis ◽

Protein Specificity

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Probing the interactions of an acyl carrier protein domain from the 6-deoxyerythronolide B synthase

Protein Science ◽

10.1002/pro.652 ◽

2011 ◽

Vol 20 (7) ◽

pp. 1244-1255 ◽

Cited By ~ 35

Author(s):

Louise K. Charkoudian ◽

Corey W. Liu ◽

Stefania Capone ◽

Shiven Kapur ◽

David E. Cane ◽

...

Keyword(s):

Acyl Carrier Protein ◽

Protein Domain ◽

Carrier Protein ◽

Deoxyerythronolide B Synthase

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Faculty Opinions recommendation of Rapid analysis of large protein-protein complexes using NMR-derived orientational constraints: the 95 kDa complex of LpxA with acyl carrier protein.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1020790.250631 ◽

2004 ◽

Author(s):

Antonio Rosato

Keyword(s):

Acyl Carrier Protein ◽

Protein Complexes ◽

Rapid Analysis ◽

Carrier Protein ◽

Large Protein

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Faculty Opinions recommendation of Defective pollen wall is required for anther and microspore development in rice and encodes a fatty acyl carrier protein reductase.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.13361956.14732054 ◽

2011 ◽

Author(s):

John Ohlrogge

Keyword(s):

Acyl Carrier Protein ◽

Fatty Acyl ◽

Pollen Wall ◽

Carrier Protein ◽

Microspore Development

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