Phase Behavior of a Phospholipid/Fatty Acid/Water Mixture Studied in Atomic Detail

2006 ◽  
Vol 128 (6) ◽  
pp. 2030-2034 ◽  
Author(s):  
Volker Knecht ◽  
Alan E. Mark ◽  
Siewert-Jan Marrink
2020 ◽  
Vol 16 ◽  
Author(s):  
Luxia Zheng ◽  
Xiong Shen ◽  
Yingchun Wang ◽  
Jian Liang ◽  
Mingming Xu ◽  
...  

Background: Phospholipids are widely used in food and pharmaceutical industry as functional excipients. In spite of the many analytical methods reported, there are very limited reports concerning systematic research and comparison of phospholipid excipients. Objective: To present a comprehensive evaluation of commercial natural phospholipid excipients (CNPEs). Methods: Seventeen batches of CNPEs from five manufacturing enterprises, isolated either from soybean or egg yolk, were investigated. The content and composition of phospholipids, fatty acids and sterols as a whole were considered as the evaluative index of CNPEs. Eight kinds of phospholipids were determined by supercritical fluid chromatography (SFC), twenty-one kinds of fatty acids were determined by gas chromatography (GC) after boron trifluoride-methanol derivatization, and nine kinds of sterols were determined by high performance liquid chromatography (HPLC) after separation and derivatization of the unsaponifiable matter. Cluster analysis was employed for classification and identification of the CNPEs. Results: The results showed that each kind of CNPEs had its characteristic content and composition of phospholipids, fatty acids and sterols. Seventeen batches of samples were divided into eight groups in cluster analysis. CNPEs of the same type from different source (soybean or egg yolk) or enterprises presented different content and composition of phospholipids, fatty acids and sterols. Conclusion: Each type of CNPEs had its characteristic content and composition of phospholipid, fatty acid and sterol. The compositions of phospholipid, fatty acid and sterol as a whole can be applied as an indicator of the quality and characteristics for CNPEs.


Author(s):  
Natascha Lewe ◽  
Syrie Hermans ◽  
Gavin Lear ◽  
Laura T. Kelly ◽  
Georgia Thomson-Laing ◽  
...  

1975 ◽  
Vol 38 (3) ◽  
pp. 513-516 ◽  
Author(s):  
R. A. Rhoades

The relative utilization of [U-14C]glucose and [1–14C]palmitate was examined in lung slices of male Long Evans hooded rats fed ad libitum and starved for 72 h. Food deprivation (72-h fast) significantly decreased [U-14C]flucose oxidation and incorporation into lung lipids. Glucose incorporation into phospholipid-fatty acid (53%) was, in proportion, more markedly reduced than into phospholipid-gluceride glycerol (33%), suggesting that glucose was being conserved for the formation of alpha-glycerol phosphate. (1–14C) palmitate utilization following fasting showed a significant 40% increase in oxidation, and a significant 16% increase in phospholipids, indicating preferential utilization of fatty acids over glucose. Phospholipid fatty acid composition, surface tension measurements and volume-pressure curves were not affected by fasting. Khe data indicate that glucose and palmitate metabolism are interrelated, and that the relative utilization of these substrates is changed to maintain essential lung lipids during an altered physiologic state.


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