Tunable Inhibition and Denaturation of α-Chymotrypsin with Amino Acid-Functionalized Gold Nanoparticles

2005 ◽  
Vol 127 (37) ◽  
pp. 12873-12881 ◽  
Author(s):  
Chang-Cheng You ◽  
Mrinmoy De ◽  
Gang Han ◽  
Vincent M. Rotello
2013 ◽  
Vol 645 ◽  
pp. 43-46
Author(s):  
Hui Qing Li ◽  
Xiu Fang Wang ◽  
Jun Zhang ◽  
Xiao Wei Di

Biomolecule functionalized gold nanoparticles offer a broad range of applications in biomedical and bioanalytical areas. In this work, we investigated the spectroscopy behavior of gold nanoparticles modified with mercapto amino acid, cysteine. We found that the interaction of gold nanoparticles with cysteine resulted in a shift in the plasmon bands to higher wavelengths at the lower concentration of cysteine and in acidity solution.


ACS Nano ◽  
2008 ◽  
Vol 2 (11) ◽  
pp. 2213-2218 ◽  
Author(s):  
Partha S. Ghosh ◽  
Chae-Kyu Kim ◽  
Gang Han ◽  
Neil S. Forbes ◽  
Vincent M. Rotello

RSC Advances ◽  
2021 ◽  
Vol 11 (37) ◽  
pp. 22691-22691
Author(s):  
Jinjin Yin ◽  
Jiuchao Wang ◽  
Xiyue Yang ◽  
Tao Wu ◽  
Huashan Wang ◽  
...  

Correction for ‘Poly(adenine)-mediated DNA-functionalized gold nanoparticles for sensitive detection of mercury ions in aqueous media’ by Jinjin Yin et al., RSC Adv., 2019, 9, 18728–18733, DOI: 10.1039/C9RA03041G.


2006 ◽  
Vol 128 (6) ◽  
pp. 1907-1913 ◽  
Author(s):  
Binil Itty Ipe ◽  
Karuvath Yoosaf ◽  
Kakkudiyil George Thomas

2021 ◽  
Author(s):  
Yimeng Li ◽  
Nicholas Ariotti ◽  
Behnaz Aghaei ◽  
Elvis Pandzic ◽  
Sylvia Ganda ◽  
...  

2021 ◽  
Vol 22 (7) ◽  
pp. 3691
Author(s):  
Oliver Schmutzler ◽  
Sebastian Graf ◽  
Nils Behm ◽  
Wael Y. Mansour ◽  
Florian Blumendorf ◽  
...  

Quantitative cellular in vitro nanoparticle uptake measurements are possible with a large number of different techniques, however, all have their respective restrictions. Here, we demonstrate the application of synchrotron-based X-ray fluorescence imaging (XFI) on prostate tumor cells, which have internalized differently functionalized gold nanoparticles. Total nanoparticle uptake on the order of a few hundred picograms could be conveniently observed with microsamples consisting of only a few hundreds of cells. A comparison with mass spectroscopy quantification is provided, experimental results are both supported and sensitivity limits of this XFI approach extrapolated by Monte-Carlo simulations, yielding a minimum detectable nanoparticle mass of just 5 pg. This study demonstrates the high sensitivity level of XFI, allowing non-destructive uptake measurements with very small microsamples within just seconds of irradiation time.


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