Catalytic Asymmetric Michael Reaction of β-Keto Esters:  Effects of the Linker Heteroatom in Linked-BINOL

2003 ◽  
Vol 125 (51) ◽  
pp. 15837-15845 ◽  
Author(s):  
Keisuke Majima ◽  
Ryo Takita ◽  
Akihiro Okada ◽  
Takashi Ohshima ◽  
Masakatsu Shibasaki
Keyword(s):  
Michael Reaction ◽  
Keto Esters ◽  
Catalytic Asymmetric ◽  
Asymmetric Michael Reaction

scholarly journals Catalytic Asymmetric Michael Reaction of β-Keto Esters: Effects of the Linker Heteroatom in Linked-BINOL.

ChemInform ◽  
2004 ◽  
Vol 35 (17) ◽  
Author(s):  
Keisuke Majima ◽  
Ryo Takita ◽  
Akihiro Okada ◽  
Takashi Ohshima ◽  
Masakatsu Shibasaki
Keyword(s):  
Michael Reaction ◽  
Keto Esters ◽  
Catalytic Asymmetric ◽  
Asymmetric Michael Reaction

Multiselective Catalytic Asymmetric Reactions Using α-Keto Esters as Pronucleophiles

Synlett ◽  
2019 ◽  
Vol 31 (06) ◽  
pp. 523-534 ◽  
Author(s):  
Yoshihiro Sohtome ◽  
Mikiko Sodeoka
Keyword(s):  
Transition Metal Complexes ◽  
Michael Reaction ◽  
Complex Molecules ◽  
Asymmetric Catalytic ◽  
Keto Esters ◽  
High Tunability ◽  
Molecular Complexity ◽  
Catalytic Asymmetric ◽  
Late Transition ◽  
Asymmetric Michael Reaction

In the reactions of simple starting materials, precise catalytic control of the stereochemical outcome (enantio- and diastereoselectivity), as well as chemoselectivity and regioselectivity is an efficient approach to increase molecular complexity with minimal use of protecting groups. Here, we introduce our ongoing studies on asymmetric catalytic reactions using α-keto esters as pronucleophiles or formal 1,3-dipolarophiles. Capitalizing on the high tunability of our late transition-metal complexes with a suitable basic counteranion, we have established a range of multiselective catalytic protocols starting from α-keto esters to provide a wide variety of stereochemically complex molecules incorporating adjacent stereocenters.1 Introduction2 Catalytic Asymmetric Monofluorination with NSFI3 Catalytic Asymmetric Michael Reaction with Nitroolefins4 Catalytic Asymmetric [3+2] Cycloaddition with (E)-Nitrones5 Catalytic Asymmetric [3+2] Cycloaddition with Nitrile Oxides6 Summary

2-Azanorbornane-Based Amino Alcohol Organocatalysts for Asymmetric Michael Reaction of β-Keto Esters with Nitroolefins

2019 ◽  
Vol 2019 (24) ◽  
pp. 3882-3889 ◽  
Author(s):  
Rei Togashi ◽  
Madhu Chennapuram ◽  
Chigusa Seki ◽  
Yuko Okuyama ◽  
Eunsang Kwon ◽  
...  
Keyword(s):  
Amino Alcohol ◽  
Michael Reaction ◽  
Keto Esters ◽  
Asymmetric Michael Reaction

scholarly journals Highly Enantioselective Construction of Quaternary Stereocenters onβ-Keto Esters by Phase-Transfer Catalytic Asymmetric Alkylation and Michael Reaction

2003 ◽  
Vol 115 (34) ◽  
pp. 4111-4111 ◽  
Author(s):  
Takashi Ooi ◽  
Takashi Miki ◽  
Mika Taniguchi ◽  
Misato Shiraishi ◽  
Mifune Takeuchi ◽  
...  
Keyword(s):  
Michael Reaction ◽  
Phase Transfer ◽  
Asymmetric Alkylation ◽  
Keto Esters ◽  
Catalytic Asymmetric ◽  
Quaternary Stereocenters

Catalytic Asymmetric Michael Reaction of 5H-Oxazol-4-Ones with α,β-Unsaturated Acyl Imidazoles

2015 ◽  
Vol 21 (48) ◽  
pp. 17234-17238 ◽  
Author(s):  
Bangzhi Zhang ◽  
Fengxia Han ◽  
Linqing Wang ◽  
Dan Li ◽  
Dongxu Yang ◽  
...  
Keyword(s):  
Michael Reaction ◽  
Unsaturated Acyl ◽  
Catalytic Asymmetric ◽  
Asymmetric Michael Reaction

ChemInform Abstract: The Catalytic Asymmetric Michael Reaction of Tin(II) Enethiolates.

ChemInform ◽  
1988 ◽  
Vol 19 (52) ◽  
Author(s):  
T. YURA ◽  
N. IWASAWA ◽  
K. NARASAKA ◽  
T. MUKAIYAMA
Keyword(s):  
Michael Reaction ◽  
Catalytic Asymmetric ◽  
Asymmetric Michael Reaction
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