A Highly Efficient Three-Component Coupling of Aldehyde, Alkyne, and Amines via C−H Activation Catalyzed by Gold in Water

2003 ◽  
Vol 125 (32) ◽  
pp. 9584-9585 ◽  
Author(s):  
Chunmei Wei ◽  
Chao-Jun Li
Keyword(s):  
Highly Efficient ◽  
Three Component Coupling

Facile Access to 3,4-Disubstituted 2H-Chromenes via Domino [4+2] Annulation

Synthesis ◽  
2020 ◽  
Author(s):  
Sure Siva Prasad ◽  
Dirgha Raj Joshi ◽  
Ikyon Kim
Keyword(s):  
Lewis Acid ◽  
Triethyl Phosphite ◽  
Synthetic Route ◽  
One Pot ◽  
Highly Efficient ◽  
Three Component Coupling

AbstractA highly efficient synthetic route to polysubstituted 2H-chromenes was developed utilizing a domino O-alkylation/intramolecular Horner–Wadsworth–Emmons (HWE) olefination of diarylmethylphosphonates, which were readily accessed via Lewis acid mediated one-pot three-component coupling of aldehydes, phenols, and triethyl phosphite.

KOtBu-Promoted Three-Component Coupling of Aldehydes and Alkynes:  Highly Efficient Synthesis of 1-En-4-yn-3-ols and 2-En-4-yn-1-ols

2006 ◽  
Vol 71 (11) ◽  
pp. 4343-4345 ◽  
Author(s):  
Shao-Hua Wang ◽  
Yong-Qiang Tu ◽  
Peng Chen ◽  
Xiang-Dong Hu ◽  
Fu-Min Zhang ◽  
...  
Keyword(s):  
Efficient Synthesis ◽  
Highly Efficient ◽  
Three Component Coupling
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