A Novel and Rapid Encoding Method Based on Mass Spectrometry for “One-Bead-One-Compound” Small Molecule Combinatorial Libraries

2003 ◽  
Vol 125 (20) ◽  
pp. 6180-6188 ◽  
Author(s):  
Aimin Song ◽  
Jinhua Zhang ◽  
Carlito B. Lebrilla ◽  
Kit S. Lam
Keyword(s):  
Mass Spectrometry ◽  
Small Molecule ◽  
Combinatorial Libraries ◽  
Encoding Method

Mass Spectrometry Signal Amplification Method for Attomolar Detection of Antigens Using Small-Molecule-Tagged Gold Microparticles

2008 ◽  
Vol 120 (49) ◽  
pp. 9660-9663 ◽  
Author(s):  
Jung Rok Lee ◽  
Juhee Lee ◽  
Sang Kyung Kim ◽  
Kwang Pyo Kim ◽  
Hyung Soon Park ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Small Molecule ◽  
Signal Amplification ◽  
Amplification Method

Screening Solution-Phase Combinatorial Libraries Using Pulsed Ultrafiltration/Electrospray Mass Spectrometry

1997 ◽  
Vol 40 (25) ◽  
pp. 4006-4012 ◽  
Author(s):  
Yong-Zhong Zhao ◽  
Richard B. van Breemen ◽  
Dejan Nikolic ◽  
Chao-Ran Huang ◽  
Charles P. Woodbury ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Electrospray Mass Spectrometry ◽  
Combinatorial Libraries ◽  
Solution Phase

Matrix-enhanced nanostructure initiator mass spectrometry (ME-NIMS) for small molecule detection and imaging

2016 ◽  
Vol 8 (46) ◽  
pp. 8234-8240 ◽  
Author(s):  
Tara N. Moening ◽  
Victoria L. Brown ◽  
Lin He
Keyword(s):  
Mass Spectrometry ◽  
Small Molecule ◽  
Tissue Imaging ◽  
Enhanced Sensitivity ◽  
Ms Imaging ◽  
Small Molecule Detection

ME-NIMS MS imaging (right): significantly enhanced sensitivity over conventional NIMS (left) in tissue imaging.

Capture Compound Mass Spectrometry: A Technology for the Investigation of Small Molecule Protein Interactions

2007 ◽  
Vol 5 (3) ◽  
pp. 381-390 ◽  
Author(s):  
Hubert Köster ◽  
Daniel P. Little ◽  
Peng Luan ◽  
Rolf Muller ◽  
Suhaib M. Siddiqi ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Small Molecule ◽  
Protein Interactions
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