Highly Effective Chiral Ortho-Substituted BINAPO Ligands (o-BINAPO):  Applications in Ru-Catalyzed Asymmetric Hydrogenations of β-Aryl-Substituted β-(Acylamino)acrylates and β-Keto Esters

2002 ◽  
Vol 124 (18) ◽  
pp. 4952-4953 ◽  
Author(s):  
Yong-Gui Zhou ◽  
Wenjun Tang ◽  
Wen-Bo Wang ◽  
Wenge Li ◽  
Xumu Zhang
Keyword(s):  
Keto Esters ◽  
Highly Effective ◽  
Asymmetric Hydrogenations

Developing chiral phosphorus ligands for asymmetric hydrogenations

2010 ◽  
Vol 82 (7) ◽  
pp. 1429-1441 ◽  
Author(s):  
Wei Li ◽  
Guohua Hou ◽  
Xianfeng Sun ◽  
Gao Shang ◽  
Weicheng Zhang ◽  
...  
Keyword(s):  
Phosphine Ligands ◽  
Chiral Ligands ◽  
Phosphorus Ligands ◽  
Keto Esters ◽  
Asymmetric Hydrogenations ◽  
Dehydroamino Acid

Chiral rigid and electron-donating phosphocyclic phosphine ligands and modular atropisomeric biaryl phosphine ligands were designed and synthesized. The performance of these chiral ligands in the asymmetric hydrogenations of prochiral dehydroamino acid derivatives, enamides, imines, keto esters, and ketones has been demonstrated to be excellent.

Oral budenosid is highly effective in the treatment of collagenous colitis: A randomized, double-blind, placebo-controlled, multicenter trial

2001 ◽  
Vol 120 (5) ◽  
pp. A40-A40 ◽  
Author(s):  
S MIEHLKE ◽  
P HEYMER ◽  
T OCHSENKUEHN ◽  
E BAESTLEIN ◽  
G YARIAN ◽  
...  
Keyword(s):  
Collagenous Colitis ◽  
Multicenter Trial ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Highly Effective

Novel Drugs Highly Effective in Resistant HIV

2007 ◽  
Vol 38 (4) ◽  
pp. 9
Author(s):  
TIMOTHY F. KIRN
Keyword(s):  
Novel Drugs ◽  
Highly Effective
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