Derivatives of Coumaran. VIII. Reductions in the Coumaranone Series. A New Synthesis of Dihydrotubanol

1941 ◽  
Vol 63 (8) ◽  
pp. 2134-2137 ◽  
Author(s):  
R. L. Shriner ◽  
Michael Witte
Keyword(s):  
New Synthesis ◽  
Derivatives Of

scholarly journals Synthesis of 2-aminosuberic acid derivatives as components of some histone deacetylase inhibiting cyclic tetrapeptides

2017 ◽  
Vol 13 ◽  
pp. 2153-2156 ◽  
Author(s):  
Shital Kumar Chattopadhyay ◽  
Suman Sil ◽  
Jyoti Prasad Mukherjee
Keyword(s):  
Amino Acid ◽  
Histone Deacetylase ◽  
Building Block ◽  
Suberic Acid ◽  
Metathesis Reaction ◽  
Cross Metathesis ◽  
Important Amino Acid ◽  
New Synthesis ◽  
Cyclic Tetrapeptides ◽  
Derivatives Of

A new synthesis of the important amino acid 2-aminosuberic acid from aspartic acid is reported. The methodology involves the alternate preparation of (S)-2-aminohept-6-enoate ester as a building block and its diversification through a cross-metathesis reaction to prepare the title compounds. The utility of the protocol is demonstrated through the preparation of three suberic acid derivatives of relevance to the design and the synthesis of peptides of biological relevance.

New Synthesis of Derivatives of 6-Aryl-3-methyl-6,7-dihydro-5H-[1,2,4]triazolo[3,4-b] [1,3,4]thiadiazine-7-carboxylic Acid.

ChemInform ◽  
2004 ◽  
Vol 35 (8) ◽  
Author(s):  
V. A. Yanchenko ◽  
V. V. Malyshev ◽  
A. M. Demchenko ◽  
M. O. Lozinskii
Keyword(s):  
Carboxylic Acid ◽  
New Synthesis ◽  
Derivatives Of

The Preparation and Ammonolysis of α-Halogen Derivatives of ε-Caprolactam. A New Synthesis of Lysine1

1958 ◽  
Vol 80 (23) ◽  
pp. 6238-6244 ◽  
Author(s):  
William C. Francis ◽  
J. Robert Thornton ◽  
James C. Werner ◽  
T. R. Hopkins
Keyword(s):  
New Synthesis ◽  
Derivatives Of

N-Methylamino Acids in Peptide Synthesis. II. A New Synthesis of N-Benzyloxycarbonyl, N-Methylamino Acids

1973 ◽  
Vol 51 (12) ◽  
pp. 1915-1919 ◽  
Author(s):  
John R. McDermott ◽  
N. Leo Benoiton
Keyword(s):  
Amino Acids ◽  
Methyl Iodide ◽  
Peptide Synthesis ◽  
Side Chains ◽  
Butyl Group ◽  
New Synthesis ◽  
Derivatives Of

Reaction of N-benzyloxycarbonyl derivatives of aliphatic amino acids, and threonine, aspartic, and glutamic acids whose side-chains were protected with the t-butyl group, gave the corresponding N-methylamino acid derivatives in good yields. The methionine derivative could be obtained by using only one mol of methyl iodide. Derivatives of threonine, and aspartic and glutamic acids whose side-chains were not protected could not be methylated. Analysis of the crude products of methylation in three cases showed that they contained 0–1% of racemized material.

A New Synthesis of some Derivatives of 4,4′-Stilbenediol

Nature ◽  
1953 ◽  
Vol 171 (4356) ◽  
pp. 746-747
Author(s):  
P. M. BHARGAVA ◽  
S. HUSAIN ZAHEER
Keyword(s):  
New Synthesis ◽  
Derivatives Of
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