A NEW SYNTHETIC METHOD OF PROTEIN ANALOGS HAVING PERIODIC ARRANGEMENT OF AMINO ACIDS

1954 ◽  
Vol 76 (10) ◽  
pp. 2846-2848 ◽  
Author(s):  
Junzo Noguchi ◽  
Tadao Hayakawa
Keyword(s):  
Amino Acids ◽  
Synthetic Method ◽  
Periodic Arrangement

scholarly journals One-Pot Synthesis of α-Substituted Acrylates

SynOpen ◽  
2018 ◽  
Vol 02 (02) ◽  
pp. 0161-0167
Author(s):  
Magdalini Matziari ◽  
Yixin Xie
Keyword(s):  
Amino Acids ◽  
Reaction Times ◽  
Synthetic Method ◽  
One Pot ◽  
Biologically Relevant ◽  
Mild Conditions ◽  
One Pot Synthesis ◽  
Acrylic Esters ◽  
Natural Amino Acids ◽  
Work Up

A simple and efficient synthetic method towards α-substituted acrylic esters has been developed using the Horner–Wadsworth–Emmons (HWE) reaction with HCHO after alkylation of phosphonoacetates in a one-pot reaction. This method allows the smooth introduction of various side-chains, such as natural amino acids and other biologically relevant substituents. The use of mild conditions, inexpensive reagents, short reaction times and simple work-up and purification steps provides an effective and general alternative to cumbersome multistep and low-yielding procedures described to date.

scholarly journals Studies on the Synthetic Method of Protein-Analogs. II. Thermal Decomposition of N-Carbothiophenyl-Amino Acids.

1954 ◽  
Vol 75 (6) ◽  
pp. 639-640
Author(s):  
Junzo Noguchi ◽  
Shohei Ishino ◽  
Kiyoshi Miyamori ◽  
Masatomo Asai ◽  
Tadao Hayakawa ◽  
...  
Keyword(s):  
Amino Acids ◽  
Thermal Decomposition ◽  
Synthetic Method
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