The Relationship of Charge Density, Antibacterial Activity and Micelle Formation of Quaternary Ammonium Salts

1955 ◽  
Vol 77 (16) ◽  
pp. 4264-4266 ◽  
Author(s):  
J. A. Cella ◽  
L. A. Harriman ◽  
D. N. Eggenberger ◽  
H. J. Harwood
Keyword(s):  
Antibacterial Activity ◽  
Charge Density ◽  
Quaternary Ammonium ◽  
Micelle Formation ◽  
Quaternary Ammonium Salts ◽  
Ammonium Salts ◽  
Relationship Of ◽  
The Relationship

Synthesis, surface properties, and antibacterial activity of polysiloxane quaternary ammonium salts containing epoxy group

2015 ◽  
Vol 293 (7) ◽  
pp. 1971-1981 ◽  
Author(s):  
Xiao Cui ◽  
Congde Qiao ◽  
Shijie Wang ◽  
Yunqiao Ding ◽  
Chuanming Hao ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Surface Properties ◽  
Quaternary Ammonium ◽  
Epoxy Group ◽  
Quaternary Ammonium Salts ◽  
Ammonium Salts

scholarly journals Antibacterial activity of gemini quaternary ammonium salts

2013 ◽  
Vol 350 (2) ◽  
pp. 190-198 ◽  
Author(s):  
Ewa Obłąk ◽  
Agata Piecuch ◽  
Katarzyna Guz-Regner ◽  
Ewa Dworniczek
Keyword(s):  
Antibacterial Activity ◽  
Quaternary Ammonium ◽  
Quaternary Ammonium Salts ◽  
Ammonium Salts

Quaternized poly(2-(dimethylamino)ethyl methacrylate)-grafted agarose copolymers for multipurpose antibacterial applications

RSC Advances ◽  
2015 ◽  
Vol 5 (76) ◽  
pp. 61742-61751 ◽  
Author(s):  
Li Qun Xu ◽  
Ning Ning Li ◽  
Jiu Cun Chen ◽  
Guo Dong Fu ◽  
En-Tang Kang
Keyword(s):  
Antibacterial Activity ◽  
Quaternary Ammonium ◽  
Quaternary Ammonium Salts ◽  
Ammonium Salts ◽  
Ethyl Methacrylate ◽  
Good Antibacterial Activity ◽  
Solution Form ◽  
Antibacterial Surfaces

Polymeric quaternary ammonium salts-functionalized agarose not only exhibit good antibacterial activity in solution form, but also can be solidified to construct antibacterial surfaces.

scholarly journals Design, Synthesis, Antibacterial, and Antitumor Activity of Linear Polyisocyanide Quaternary Ammonium Salts with Different Structures and Chain Lengths

Molecules ◽  
2021 ◽  
Vol 26 (18) ◽  
pp. 5686
Author(s):  
Hongguang Zhang ◽  
Lijia Liu ◽  
Peng Hou ◽  
Jun Liu ◽  
Shuang Fu
Keyword(s):  
Antibacterial Activity ◽  
Quaternary Ammonium ◽  
Main Chain ◽  
Quaternary Ammonium Salts ◽  
Polymer Materials ◽  
Ammonium Salts ◽  
Organic Polymer ◽  
Side Chain ◽  
E Coli ◽  
Chain Lengths

The development of organic polymer materials for disinfection and sterilization is thought of as one of the most promising avenues to solve the growth and spread of harmful microorganisms. Here, a series of linear polyisocyanide quaternary ammonium salts (L-PQASs) with different structures and chain lengths were designed and synthesized by polymerization of phenyl isocyanide monomer containing a 4-chloro-1-butyl side chain followed by quaternary amination salinization. The resultant compounds were characterized by 1H NMR and FT-IR. The antibacterial activity of L-PQASs with different structures and chain lengths against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) was evaluated by determining the minimum inhibitory concentrations (MICs). The L-POcQAS-M50 has the strongest antimicrobial activity with MICs of 27 μg/mL against E. coli and 32 μg/mL against S. aureus. When the L-PQASs had the same polymerization degree, the order of the antibacterial activity of the L-PQASs was L-POcQAS-Mn > L-PBuQAS-Mn > L-PBnQAS-Mn > L-PDBQAS-Mn (linear, polyisocyanide quaternary ammonium salt, monomer, n = 50,100). However, when L-PQASs had the same side chain, the antibacterial activity reduced with the increase of the molecular weight of the main chain. These results demonstrated that the antibacterial activity of L-PQASs was dependent on the structure of the main chain and the length of the side chain. In addition, we also found that the L-POcQAS-M50 had a significant killing effect on MK-28 gastric cancer cells.

Synthesis, physiochemical property and antibacterial activity of gemini quaternary ammonium salts with a rigid spacer

RSC Advances ◽  
2016 ◽  
Vol 6 (20) ◽  
pp. 16507-16515 ◽  
Author(s):  
S. Q. Fu ◽  
J. W. Guo ◽  
X. Zhong ◽  
Z. Yang ◽  
X. F. Lai
Keyword(s):  
Antibacterial Activity ◽  
Quaternary Ammonium ◽  
Quaternary Ammonium Salts ◽  
Ammonium Salts ◽  
Physiochemical Property ◽  
Rigid Spacer

Aggregate morphologies of GQASs change from vesicles and micelles to network aggregates and then to globular vesicles with increase of concentration.

Sign in / Sign up

Export Citation Format

Share Document