Diborane from the Sodium Borohydride-Sulfuric Acid Reaction

1959 ◽  
Vol 81 (23) ◽  
pp. 6167-6168 ◽  
Author(s):  
H. G. Weiss ◽  
I. Shapiro
Keyword(s):  
Sulfuric Acid ◽  
Sodium Borohydride ◽  
Acid Reaction

scholarly journals Effective approach to a synthesis of fluorine-containing 4-acylamino-4,5,6,7-tetrahydrobenzisoxazoles

2020 ◽  
Vol 63 (6) ◽  
pp. 716-720
Author(s):  
T. S. Khlebnicova ◽  
Yu. A. Piven ◽  
I. I. Gerus ◽  
A. E. Sorochinsky ◽  
F. A. Lakhvich
Keyword(s):  
Acetic Acid ◽  
Sulfuric Acid ◽  
Sodium Borohydride ◽  
Ritter Reaction ◽  
The Ritter Reaction

On the example of synthesis of 4-acetylamino-3-fluoroalkyl(aryl)-4,5,6,7-tetrahydro-1,2-benzisoxazoles, the effective approach to a synthesis of novel 4-acylamino-4,5,6,7-tetrahydro-1,2-benzisoxazoles is proposed. 3-Fluoroalkyl(aryl)- 6,7-dihydro-1,2-benzisoxazol-4-ones were reduced by a sodium borohydride in isopropanol to obtain 3-fluoroalkyl(aryl)- 4,5,6,7-tetrahydro-1,2-benzisoxazol-4-ols that in the conditions of the Ritter reaction (acetonitrile, acetic acid, sulfuric acid) gave target 4-acylamino derivatives with 80–94 % yields.

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