Crystalline Racemic Calcium Pantothenate

Jared H. Ford

doi:10.1021/ja01212a510

The Pharmacokinetics of Orally Administered Calcium Pantothenate in Healthy Adults

10.29011/jvm-106.100006 ◽

2021 ◽

Keyword(s):

Healthy Adults ◽

Calcium Pantothenate

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Effect of Varying the Intake of Calcium Pantothenate of Rats During Pregnancy

Journal of Nutrition ◽

10.1093/jn/53.3.341 ◽

1954 ◽

Vol 53 (3) ◽

pp. 341-350 ◽

Cited By ~ 3

Author(s):

Gladys Everson ◽

Lois Northrop ◽

Nam Young Chung ◽

Robert Getty ◽

Cecelia Pudelkewicz

Keyword(s):

Calcium Pantothenate

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Automated Fluorometric Analysis of Calcium Pantothenate in Multivitamin Preparations

Journal of AOAC INTERNATIONAL ◽

10.1093/jaoac/61.3.720 ◽

1978 ◽

Vol 61 (3) ◽

pp. 720-726

Author(s):

Ram B Roy ◽

Anthony Buccafuri

Keyword(s):

Acid Solution ◽

Boric Acid ◽

Fluorescence Intensity ◽

Analytical Data ◽

Boric Acid Solution ◽

Calcium Pantothenate ◽

Magnesium Trisilicate ◽

On Line ◽

The Mean ◽

Fluorometric Analysis

Abstract An automated fluorometric procedure is described for assaying calcium pantothenate in multivitamin preparations. Sample extracts containing calcium pantothenate are treated on-line with a slurry of magnesium trisilicate which removes any interfering riboflavin that may be present. The nitrate is resampled, mixed online with a slurry of Dowex 50W-X4 (H+) which removes any interfering β-alanine that may be present, and dialyzed. Dialysates are hydrolyzed in an alkaline medium and reacted with a mixture of o-phthalaldehyde and 2-mercaptoethanoI in boric acid solution. The fluorescence intensity due to the formation of a fluorogenic compound is measured at 455 nm after excitation at 350 nm. The procedure developed is capable of analyzing 20 samples/hr. Analytical data indicate that calcium pantothenate is assayed reliably both from real and synthetic multivitamin preparations. The mean recovery of calcium pantothenate added to sample solutions of tablet composites was 95.4%.

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Calcium pantothenate modulates gene expression in proliferating human dermal fibroblasts

Experimental Dermatology ◽

10.1111/j.1600-0625.2009.00884.x ◽

2009 ◽

Vol 18 (11) ◽

pp. 969-978 ◽

Cited By ~ 23

Author(s):

Tonio Wiederholt ◽

Ruth Heise ◽

Claudia Skazik ◽

Yvonne Marquardt ◽

Sylvia Joussen ◽

...

Keyword(s):

Gene Expression ◽

Dermal Fibroblasts ◽

Human Dermal Fibroblasts ◽

Calcium Pantothenate

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Simple Colorimetric Method for Determination of Thiamine Hydrochloride in Pharmauceuticals

Journal of AOAC INTERNATIONAL ◽

10.1093/jaoac/68.1.83 ◽

1985 ◽

Vol 68 (1) ◽

pp. 83-85

Author(s):

Ramesh T Sane ◽

Vipul J Doshi ◽

Swati Jukar ◽

Sanjay K Joshi ◽

Satish V Sawant ◽

...

Keyword(s):

Liver Extract ◽

Colorimetric Method ◽

Dosage Forms ◽

Vitamin B ◽

Thiamine Hydrochloride ◽

Calcium Pantothenate ◽

Statistical Validation ◽

Alkaline Conditions ◽

The Stability

Abstract A simple colorimetric method is described for the determination of thiamine hydrochloride (vitamin B,) in dosage forms. The method is based on measurement of a yellow complex formed when thiamine HC1 is treated with /7-methylaminophenol sulfate (Metol) under alkaline conditions. Compounds such as vitamins A, B2, B6, B,2, C, D, and E, and niacinamide, citric acid, liquid glucose, calcium pantothenate, biotin, liver extract, and folic acid do not interfere in the reaction. Extracting the complex into chloroform before quantitation enhances the stability of the reaction product and removes interference of watersoluble colored constituents in syrup samples. Statistical validation shows that the method is precise and accurate. Results agree well with those obtained by other methods in the literature

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