A Fluorescence-Based Method for Direct Measurement of Submicrosecond Intramolecular Contact Formation in Biopolymers:  An Exploratory Study with Polypeptides

2002 ◽  
Vol 124 (4) ◽  
pp. 556-564 ◽  
Author(s):  
Robert R. Hudgins ◽  
Fang Huang ◽  
Gabriela Gramlich ◽  
Werner M. Nau
Keyword(s):  
Direct Measurement ◽  
Exploratory Study ◽  
Intramolecular Contact ◽  
Contact Formation

scholarly journals Measurement of Submicrosecond Intramolecular Contact Formation in Peptides at the Single-Molecule Level

2003 ◽  
Vol 125 (18) ◽  
pp. 5324-5330 ◽  
Author(s):  
Hannes Neuweiler ◽  
Andreas Schulz ◽  
Martin Böhmer ◽  
Jörg Enderlein ◽  
Markus Sauer
Keyword(s):  
Single Molecule ◽  
Intramolecular Contact ◽  
Single Molecule Level ◽  
Contact Formation

scholarly journals Collapse Of Rat And Human Amylin From Nanosecond-resolved Intramolecular Contact Formation

2009 ◽  
Vol 96 (3) ◽  
pp. 319a
Author(s):  
Sara M. Vaiana ◽  
Robert B. Best ◽  
Wai-Ming Yau ◽  
William A. Eaton ◽  
James Hofrichter
Keyword(s):  
Intramolecular Contact ◽  
Contact Formation ◽  
Human Amylin

scholarly journals Measuring the rate of intramolecular contact formation in polypeptides

2000 ◽  
Vol 97 (13) ◽  
pp. 7220-7225 ◽  
Author(s):  
L. J. Lapidus ◽  
W. A. Eaton ◽  
J. Hofrichter
Keyword(s):  
Intramolecular Contact ◽  
Contact Formation

scholarly journals N-Terminal Decarboxylation as a Probe for Intramolecular Contact Formation in γ-Glu-(Pro)n-Met Peptides

2020 ◽  
Vol 124 (37) ◽  
pp. 8082-8098
Author(s):  
Piotr Filipiak ◽  
Krzysztof Bobrowski ◽  
Gordon L. Hug ◽  
Christian Schöneich ◽  
Bronislaw Marciniak
Keyword(s):  
Intramolecular Contact ◽  
Contact Formation

Kinetics of Intramolecular Contact Formation in a Denatured Protein

2003 ◽  
Vol 332 (1) ◽  
pp. 9-12 ◽  
Author(s):  
Marco Buscaglia ◽  
Benjamin Schuler ◽  
Lisa J. Lapidus ◽  
William A. Eaton ◽  
James Hofrichter
Keyword(s):  
Intramolecular Contact ◽  
Contact Formation ◽  
Denatured Protein ◽  
Kinetics Of

Classifying Disfluencies in Preschool- and School-Age Spanish–English Bilinguals Who Do Not Stutter: An Exploratory Study

2020 ◽  
Vol 5 (1) ◽  
pp. 119-130
Author(s):  
Raúl Rojas ◽  
Farzan Irani
Keyword(s):  
Exploratory Study ◽  
Evidence Base ◽  
Medium Effect ◽  
Bilingual Children ◽  
Linear Regression Models ◽  
Cross Sectional ◽  
Total Percentage ◽  
Narrative Production ◽  
Language Measures ◽  
Mean Length Of Utterance

Purpose This exploratory study examined the language skills and the type and frequency of disfluencies in the spoken narrative production of Spanish–English bilingual children who do not stutter. Method A cross-sectional sample of 29 bilingual students (16 boys and 13 girls) enrolled in grades prekindergarten through Grade 4 produced a total of 58 narrative retell language samples in English and Spanish. Key outcome measures in each language included the percentage of normal (%ND) and stuttering-like (%SLD) disfluencies, percentage of words in mazes (%MzWds), number of total words, number of different words, and mean length of utterance in words. Results Cross-linguistic, pairwise comparisons revealed significant differences with medium effect sizes for %ND and %MzWds (both lower for English) as well as for number of different words (lower for Spanish). On average, the total percentage of mazed words was higher than 10% in both languages, a pattern driven primarily by %ND; %SLDs were below 1% in both languages. Multiple linear regression models for %ND and %SLD in each language indicated that %MzWds was the primary predictor across languages beyond other language measures and demographic variables. Conclusions The findings extend the evidence base with regard to the frequency and type of disfluencies that can be expected in bilingual children who do not stutter in grades prekindergarten to Grade 4. The data indicate that %MzWds and %ND can similarly index the normal disfluencies of bilingual children during narrative production. The potential clinical implications of the findings from this study are discussed.

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