A New Reaction of Diborane with Carbon Monoxide Catalyzed by Sodium Borohydride. A Convenient Synthesis of Trimethylboroxide

1966 ◽  
Vol 88 (11) ◽  
pp. 2606-2607 ◽  
Author(s):  
Michael W. Rathke ◽  
Herbert C. Brown
Keyword(s):  
Carbon Monoxide ◽  
Sodium Borohydride ◽  
Convenient Synthesis

Convenient Synthesis of Primary Selenoamides from Aryl Nitriles, Selenium, and Sodium Borohydride

1994 ◽  
Vol 24 (12) ◽  
pp. 1761-1765 ◽  
Author(s):  
Xue-Rong Zhao ◽  
Ming-De Ruan ◽  
Wei-Qiang Fan ◽  
Xun-Jun Zhou
Keyword(s):  
Sodium Borohydride ◽  
Convenient Synthesis ◽  
Aryl Nitriles

ChemInform Abstract: Convenient Synthesis of Primary Selenoamides from Aryl Nitriles, Selenium, and Sodium Borohydride.

ChemInform ◽  
2010 ◽  
Vol 25 (50) ◽  
pp. no-no
Author(s):  
X.-R. ZHAO ◽  
M.-D. RUAN ◽  
W.-Q. FAN ◽  
X.-J. ZHOU
Keyword(s):  
Sodium Borohydride ◽  
Convenient Synthesis ◽  
Aryl Nitriles

Tris(trimethylphosphine)cobalt(0) Compounds Containing Azaolefinic Ligands — Syntheses and Structures of Benzo[c]cinnoline and Phenylisocyanate Complexes

1993 ◽  
Vol 48 (6) ◽  
pp. 785-793 ◽  
Author(s):  
Hans-Friedrich Klein ◽  
Michael Helwig ◽  
Michael Karnop ◽  
Herbert König ◽  
Birgit Hammerschmitt ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Carbon Monoxide ◽  
Cobalt Atom ◽  
Cyclic Dimer ◽  
X Ray ◽  
Convenient Synthesis ◽  
Mononuclear Cobalt ◽  
Structure Determinations

Mononuclear cobalt(0) complexes Co(η2-azaolefin)(PMe3)3 (azaolefin = benzo[c]cinnoline (1), p-dimethylamino-phenyl(phenyl)diazene (2), 1/2 diazobenzene (3), bis(p-tolyl)diazene (4), bis(p-fluorphenyl)diazene (5), bis(p-trifluoromethyl-phenyl)diazene (6), phenylisocyanate (7)) are obtained from Co(cyclo-C5H8)(PMe3)3 by substitution of the olefin. X-ray crystal structure determinations of 1 and 7 show tetrahedral arrangements of ligands around the cobalt atom. By reaction with carbon monoxide carbonyl(phosphine)cobalt(0) complexes are formed. 7 catalyses the cyclotrimerization of phenylisocyanate, while with CoCl(PMe3)3 as a catalyst the cyclic dimer of phenylisocyanate is selectively formed. A convenient synthesis for CoCl(PMe3)3 is described.

Reduction of Ketene DithioacetalS,S-Dioxides with Sodium Borohydride and Its Application to a Convenient Synthesis of Alkyl Arylmethyl Ketones

1986 ◽  
Vol 15 (9) ◽  
pp. 1597-1598 ◽  
Author(s):  
Katsuyuki Ogura ◽  
Kazuo Ohtsuki ◽  
Kazumasa Takahashi ◽  
Hirotada Iida
Keyword(s):  
Sodium Borohydride ◽  
Ketene Dithioacetals ◽  
Convenient Synthesis

scholarly journals A convenient synthesis of labelled rhodopsin and studies on its active site

1970 ◽  
Vol 119 (3) ◽  
pp. 359-366 ◽  
Author(s):  
M. D. Hirtenstein ◽  
M. Akhtar
Keyword(s):  
Conformational Change ◽  
Sodium Borohydride ◽  
Active Site ◽  
Cetyltrimethylammonium Bromide ◽  
Chemical Reactivity ◽  
Amino Group ◽  
Polar Environment ◽  
Convenient Synthesis ◽  
First Time ◽  
Native Site

Digitonin solutions of labelled rhodopsin, containing 3H in the retinyl moiety, were prepared by two related methods. Labelled rhodopsin was also prepared for the first time in cetyltrimethylammonium bromide and purified by column chromatography. It was shown that only certain rhodopsin preparations on denaturation in the dark and the reduction with sodium borohydride gave up to 60% of the radioactivity in a fraction characterized as N-retinylphosphatidylethanolamine. Such preparations also gave a lipid-linked retinyl moiety at the metarhodopsin-I stage, but, as expected, a protein-linked retinyl moiety at the metarhodopsin-II stage. Other preparations however, gave exclusively protein-bound radioactivity at the native-rhodopsin, metarhodopsin-I and metarhodopsin-II stages. It is therefore conceivable that the formation of N-retinylphosphatidylethanolamine is due to a non-enzymic reaction resulting from the transfer of the retinyl moiety from its native site to an amino group of a favourably oriented phospholipid molecule. The only firmly established aspect of the rhodopsin active site remains the demonstration in our previous work that at the metarhodopsin-II stage the retinyl moiety is linked to an ∈-amino group of lysine. On the basis of chemical reactivity it is argued that the light-induced conversion of rhodopsin into metarhodopsin II involves a profound conformational change resulting in the dislocation of the retinylideneiminium chromophore from a non-polar environment in rhodopsin to a polar environment in metarhodopsin II.

A Facile and Convenient Synthesis of Boc-Protected 5-Carboxyspermine

2019 ◽  
Vol 16 (8) ◽  
pp. 615-618
Author(s):  
Jong-Soo Choi ◽  
Jae-Won Park ◽  
Bieong-Kil Kim ◽  
Kyung-Oh Doh ◽  
Young-Bae Seu
Keyword(s):  
Gene Therapy ◽  
Sodium Borohydride ◽  
Catalytic Reduction ◽  
Transfection Efficiency ◽  
Hereditary Disease ◽  
Simple Synthesis ◽  
Head Group ◽  
Nonviral Vectors ◽  
One Pot ◽  
Convenient Synthesis

Gene therapy is a powerful technology for treating incurable and hereditary disease in humans. In the recent years, a lot of studies have been done on the development of DNA carriers. Nonviral vectors, like liposomes, polymers, and micelles, has become common vehicles due to their safety. The key compound of DOGS, DOSPA and DOSPER is the 5-carboxyspermine which formed the poly amine head-group and carries four positive charges. In general, multivalent head-group shows more transfection efficiency than monovalent analogues. In this paper, the efficient and simple synthesis of Boc-protected 5-carboxyspermine is described. Boc-protected polyamines were synthesized from (S)- 2,5-diaminopentanoic acid monohydrochloride (L-ornithine) monohydrochloride through both cyanoethylation and direct catalytic reduction of nitriles with the combination of nickel (II) chloride, sodium borohydride and di-tert-butyl decarbonate (BOC2O) in a one-pot two-reaction.

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