Additions and Corrections - Acetic Acid as an Inhibitor in Trifluoroacetic Acid-catalyzed Aromatic Halogenations and Halogen Addition REactions.

1962 ◽  
Vol 84 (24) ◽  
pp. 4999-4999
Author(s):  
R. M. Keefer ◽  
L. J. Andrews
Keyword(s):  
Acetic Acid ◽  
Trifluoroacetic Acid ◽  
Addition Reactions ◽  
Acid Catalyzed

Acid-catalyzed migration of N4-acyl groups in cytosine derivatives

1979 ◽  
Vol 44 (6) ◽  
pp. 1819-1827 ◽  
Author(s):  
Antonín Holý
Keyword(s):  
Acetic Acid ◽  
Trifluoroacetic Acid ◽  
The Other ◽  
Aqueous Acetic Acid ◽  
Amino Group ◽  
Benzoyl Group ◽  
Benzoyl Cyanide ◽  
Acid Catalyzed ◽  
Derivatives Of ◽  
Anhydrous Acetic Acid

Heating 1-(2,3-di-O-benzoyl-β-D-arabinofuranosyl)-N4-benzoylcytosine (I) in 80% acetic acid afforded 1-(2,3-di-O-benzoyl-β-D-arabinofuranosyl)-N3-benzoylcytosine (II). Benzoylation of 5'-O-tritylcytidine (V) led to the 2',3',N4-tribenzoyl derivative VI which was refluxed with 80% acetic acid to give 2',3',N3-tribenzoylcytidine (VII). Analogously, 2',3',5',N4-tetrabenzoylcytidine (IX), prepared by benzoylation of cytidine with benzoyl cyanide, gave on reflux with 80% acetic acid 2',3',5',N3-tetrabenzoylcytidine (X). Under identical conditions, 1-methyl-N4-benzoylcytosine (XI) afforded directly 1-methyluracil (XII) .This migration takes place also in acetyl derivatives of cytosine nucleosides: 2',3',5',N4-tetraacetylcytidine (XIII) was transformed to the N3-acetylcytosine derivative XIV. On the other hand, migration of acetyl or benzoyl group from the exo-amino group of adenine has not been observed under the mentioned conditions. The migration of the N4-acyl group of cytosine derivatives proceeds best in aqueous acetic acid, more slowly also in anhydrous acetic acid, but not by action of trifluoroacetic acid in 1,2-dichloroethane.

Confirmatory Tests for Aflatoxin B1

1964 ◽  
Vol 47 (5) ◽  
pp. 801-803 ◽  
Author(s):  
Peter John Andrellos ◽  
George R Reid
Keyword(s):  
Acetic Acid ◽  
Thin Layer ◽  
Formic Acid ◽  
Thionyl Chloride ◽  
Aflatoxin B1 ◽  
Trifluoroacetic Acid ◽  
Reaction Products ◽  
Confirmatory Tests ◽  
Aflatoxin B ◽  
Layer Chromatography

Abstract Three confirmatory tests have been devised to identify aflatoxin B±. Portions of the isolated toxin are treated with formic acid-thionyl chloride, acetic acid-thionyl chloride, and trifluoroacetic acid, respectively, and aliquots of the three fluorescent reaction products are spotted on thin-layer chromatography plates. Standards treated with each of the three reagents, plus an untreated standard, are spotted on the same plate, and after development the spots are compared under ultraviolet light.

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