Transport in organic chemistry. I. Transport of amino acids through organic liquid membranes

1973 ◽  
Vol 95 (18) ◽  
pp. 6108-6110 ◽  
Author(s):  
Jean P. Behr ◽  
Jean M. Lehn
Keyword(s):  
Organic Chemistry ◽  
Amino Acids ◽  
Organic Liquid ◽  
Liquid Membranes

Transport of amino acids through organic liquid membranes. II. Aspects of the mechanism

1992 ◽  
Vol 65 (1-2) ◽  
pp. 47-50 ◽  
Author(s):  
Constantin V. Uglea ◽  
Cristinel V. Zǎnoagǎ
Keyword(s):  
Amino Acids ◽  
Organic Liquid ◽  
Liquid Membranes

Carrier‐Mediated Transport of Amino Acids Through Bulk Liquid Membranes

2004 ◽  
Vol 39 (16) ◽  
pp. 3821-3838 ◽  
Author(s):  
R. Bucci ◽  
S. Canepari ◽  
E. Cardarelli ◽  
A. M. Girelli ◽  
A. Pietrodangelo ◽  
...  
Keyword(s):  
Amino Acids ◽  
Bulk Liquid ◽  
Liquid Membranes ◽  
Carrier Mediated Transport

scholarly journals Enantioselective organocatalysis in the synthesis of biologically relevant compounds

2016 ◽  
Author(s):  
Lukasz Albrecht
Keyword(s):  
Organic Chemistry ◽  
Amino Acids ◽  
Organic Molecules ◽  
Asymmetric Induction ◽  
Chiral Catalyst ◽  
Biologically Relevant ◽  
Enantioselective Reactions ◽  
Asymmetric Organocatalysis ◽  
Biologically Relevant Molecules ◽  
Operational Simplicity

The development of methods for the preparation of biologically relevant compounds in an enantiomerically enriched form constitutes one of the most significant tasks in the contemporary organic chemistry. In particular, enantioselective reactions where prochiral substrates are converted into enantiomerically enriched products in the presence of chiral catalyst are of great importance. Recently, asymmetric organocatalysis, where simple organic molecules are used as catalysts of various enantiodifferentiating reactions, has become a highly useful synthetic tool enabling for the efficient asymmetric induction based on diverse activation modes. Herein, we report our studies on organocatalytic, enantioselective strategies for the synthesis of biologically relevant molecules such as: quaternary α-amino acids and their isoelectronic analogs α-aminophosphonates, benzo[1,5]oxazocines, α-methylidene-δ-lactones, α-alkylidene-ketones, furfural derivatives, and benzothiophenes. The devised approaches utilize readily available chiral organocatalysts to control stereo-chemical reaction outcomes. Operational simplicity, efficiency and high enantio- and diastereoselectivities are the main benefits of the developed strategies.

scholarly journals Michael Addition of Imidazole to α, β -Unsaturated Carbonyl/Cyano Compound

2018 ◽  
Vol 5 (1) ◽  
pp. 18-31
Author(s):  
Seetaram Mohapatra ◽  
Nilofar Baral ◽  
Nilima Priyadarsini Mishra ◽  
Pravati Panda ◽  
Sabita Nayak
Keyword(s):  
Organic Chemistry ◽  
Amino Acids ◽  
Anticancer Agents ◽  
Michael Addition ◽  
Addition Reaction ◽  
Bond Formation ◽  
Conjugate Addition ◽  
Michael Addition Reaction ◽  
Cyano Compounds ◽  
Nitrogen Bond

Introduction: Aza-Michael addition is an important reaction for carbon-nitrogen bond formation in synthetic organic chemistry. Expalantion: Conjugate addition of imidazole to α,β-unsaturated carbonyl/cyano compounds provides significant numbers of the biologically and synthetically interesting products, such as β-amino acids and β-lactams, which have attracted great attention for their use as key intermediates of anticancer agents, antibiotics and other drugs. Conclusion: This review addresses most significant method for the synthesis of N-substituted imidazole derivatives following Michael addition reaction of imidazole to α,β-unsaturated carbonyl/cyano compounds using ionic liquid/base/acid/enzyme as catalysts from year 2007-2017.

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