Direct observation of reversible formation of anionic .SIGMA. complexes related to transition state analogs for adenosine deaminase

Charles L. Liotta; A. Abidaud

doi:10.1021/ja00777a047

Direct observation of reversible formation of anionic .SIGMA. complexes related to transition state analogs for adenosine deaminase

Journal of the American Chemical Society ◽

10.1021/ja00777a047 ◽

1972 ◽

Vol 94 (22) ◽

pp. 7927-7928 ◽

Cited By ~ 7

Author(s):

Charles L. Liotta ◽

A. Abidaud

Keyword(s):

Transition State ◽

Adenosine Deaminase ◽

Direct Observation ◽

Sigma Complexes ◽

Transition State Analogs ◽

Reversible Formation

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The rate of formation of transition-state analogs in the active site of adenosine deaminase is encounter-controlled: implications for the mechanism

Biochemistry ◽

10.1021/bi00116a008 ◽

1992 ◽

Vol 31 (1) ◽

pp. 39-48 ◽

Cited By ~ 38

Author(s):

Linda C. Kurz ◽

Luke Moix ◽

Marian C. Riley ◽

Carl Frieden

Keyword(s):

Transition State ◽

Adenosine Deaminase ◽

Active Site ◽

Transition State Analogs

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Faculty Opinions recommendation of Anionic charge is prioritized over geometry in aluminum and magnesium fluoride transition state analogs of phosphoryl transfer enzymes.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1126855.583957 ◽

2008 ◽

Author(s):

Arieh Warshel

Keyword(s):

Transition State ◽

Magnesium Fluoride ◽

Phosphoryl Transfer ◽

Transition State Analogs ◽

Anionic Charge

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Transition state analogs for thiamin pyrophosphate-dependent enzymes.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)33570-6 ◽

1976 ◽

Vol 251 (9) ◽

pp. 2863-2866 ◽

Cited By ~ 3

Author(s):

J A Gutowski ◽

G E Lienhard

Keyword(s):

Transition State ◽

Transition State Analogs ◽

Thiamin Pyrophosphate

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Potential transition-state analogs for glycosyltransferases. Design and DFT calculations of conformational behavior

Carbohydrate Research ◽

10.1016/j.carres.2005.01.041 ◽

2005 ◽

Vol 340 (5) ◽

pp. 1051-1057 ◽

Cited By ~ 15

Author(s):

Michal Raab ◽

Stanislav Kozmon ◽

Igor Tvaroška

Keyword(s):

Dft Calculations ◽

Transition State ◽

Conformational Behavior ◽

Transition State Analogs

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Quantum chemical analysis of the interactions of transition state analogs with leucine aminopeptidase

International Journal of Quantum Chemistry ◽

10.1002/qua.1335 ◽

2001 ◽

Vol 84 (2) ◽

pp. 302-310 ◽

Cited By ~ 6

Author(s):

J. Grembecka ◽

W. A. Sokalski ◽

P. Kafarski

Keyword(s):

Chemical Analysis ◽

Transition State ◽

Quantum Chemical ◽

Leucine Aminopeptidase ◽

Quantum Chemical Analysis ◽

Transition State Analogs

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Design and Synthesis of Transition State Analogs for Induction of Hydride Transfer Catalytic Antibodies

The Journal of Organic Chemistry ◽

10.1021/jo962179v ◽

1997 ◽

Vol 62 (10) ◽

pp. 3220-3229 ◽

Cited By ~ 11

Author(s):

Josef Schröer ◽

Michel Sanner ◽

Jean-Louis Reymond

Keyword(s):

Transition State ◽

Hydride Transfer ◽

Catalytic Antibodies ◽

Design And Synthesis ◽

Transition State Analogs

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Contribution of a single hydroxyl group to transition-state discrimination by adenosine deaminase: evidence for an "entropy trap" mechanism

Biochemistry ◽

10.1021/bi00445a055 ◽

1989 ◽

Vol 28 (19) ◽

pp. 7919-7927 ◽

Cited By ~ 32

Author(s):

Warren M. Kati ◽

Richard Wolfenden

Keyword(s):

Transition State ◽

Adenosine Deaminase ◽

Hydroxyl Group ◽

State Discrimination

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Inhibition of enzymic reactions by transition state analogs: An approach for drug design

General Pharmacology The Vascular System ◽

10.1016/0306-3623(81)90002-1 ◽

1981 ◽

Vol 12 (3) ◽

pp. 129-138 ◽

Cited By ~ 16

Author(s):

T.T. Ngo ◽

G. Tunnicliff

Keyword(s):

Drug Design ◽

Transition State ◽

Transition State Analogs

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Transition state analogs of 5′-methylthioadenosine nucleosidase disrupt quorum sensing

Nature Chemical Biology ◽

10.1038/nchembio.153 ◽

2009 ◽

Vol 5 (4) ◽

pp. 251-257 ◽

Cited By ~ 114

Author(s):

Jemy A Gutierrez ◽

Tamara Crowder ◽

Agnes Rinaldo-Matthis ◽

Meng-Chiao Ho ◽

Steven C Almo ◽

...

Keyword(s):

Quorum Sensing ◽

Transition State ◽

Transition State Analogs

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TRANSITION STATE ANALOGS AS ANTIMETABOLITES

Antimetabolites in Biochemistry, Biology and Medicine ◽

10.1016/b978-0-08-024384-9.50016-6 ◽

1979 ◽

pp. 151-160 ◽

Cited By ~ 3

Author(s):

Richard Wolfenden

Keyword(s):

Transition State ◽

Transition State Analogs

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