Synthetic studies of amino acids by the use of the copper complex. I. Syntheses of .beta.-hydroxy DL-amino acids by the use of the complex of copper(II) with the Schiff base derived from glycine and pyruvic acid

1970 ◽  
Vol 92 (18) ◽  
pp. 5514-5516 ◽  
Author(s):  
Tetsuya. Ichikawa ◽  
Sadao. Maeda ◽  
Younosuke. Araki ◽  
Yoshiharu. Ishido
Keyword(s):  
Amino Acids ◽  
Schiff Base ◽  
Copper Complex ◽  
Pyruvic Acid ◽  
Complex I ◽  
Synthetic Studies

Tetranuclear Copper and Mononuclear Nickel Complex of the Schiff Base of (3Z)-3-Hydrazonobutan-2-One Oxime with Different Aromatic Carbonyl Compounds: Synthesis, Single Crystal X-Ray Structure, Catecholase Activity, Phenoxazinone Synthase Activity, Catalytic Study for the Homocoupling of Benzyl Amines

2019 ◽  
Author(s):  
Swaraj Sengupta ◽  
Sahanwaj Khan ◽  
Shyamal K. Chattopadhyay ◽  
Indrani Banerjee ◽  
Tarun K. Panda ◽  
...  
Keyword(s):  
Schiff Base ◽  
Single Crystal ◽  
Copper Complex ◽  
Carbonyl Compounds ◽  
Nickel Complex ◽  
Schiff Base Ligands ◽  
X Ray ◽  
Phenoxazinone Synthase ◽  
Catecholase Activity ◽  
Aromatic Carbonyl Compounds

Synthesis and characterisation of one trinuclear copper complex, ([Cu<sub>3</sub>L<sub>3</sub>O]ClO<sub>4</sub>) (<b>1</b>) and one nickel complex ([Ni(L'H)<sub>2</sub>(dmso)<sub>2</sub>](ClO<sub>4</sub>)<sub>2</sub>) (<b>2</b>) with Schiff base ligands: (3Z)-3-((Z)-(1-(thiophen-2-yl)ethylidene)hydrazono)butan-2-one oxime (LH) and 1-(pyridin-2-yl)ethylidene)hydrazono)butan-2-one oxime (L<sup>'</sup>H). <b>1</b> shows high catecholase activity and has also been tested as a catalyst for the synthesis of benzylimine. <b>2 </b> shows phenoxazinone synthase activity.

DNA Binding Activity of Copper Complex with Schiff Base Derived from Oligochitosan and Furfuraldehyde

2017 ◽  
Vol 38 (10) ◽  
pp. 1359-1365
Author(s):  
李小芳 LI Xiao-fang ◽  
冯小强 FENG Xiao-qiang ◽  
朱元成 ZHU Yuan-cheng
Keyword(s):  
Schiff Base ◽  
Dna Binding ◽  
Copper Complex ◽  
Binding Activity ◽  
Dna Binding Activity

scholarly journals Synthesis, Characterization, Fluorescence, Electrochemical, Antimicrobial and Cytotoxic studies of Cobalt(II), Nickel(II) and Copper(II) Complexes with N-4-Methylphenyl (2,4-dihydroxyacetophenylideneimine)

2018 ◽  
Vol 34 (4) ◽  
pp. 2008-2016
Author(s):  
Amala Subbiah ◽  
Santhi Sambamoorthy
Keyword(s):  
Breast Cancer ◽  
Schiff Base ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Copper Complex ◽  
Analytical Data ◽  
Spectral Studies ◽  
Breast Cancer Cell Lines ◽  
Planar Geometry ◽  
Mcf 7

N-4-Methylphenyl (2,4-dihydroxy acetophenylideneimine) (NMEPDHAPI) complexes of Co(II), Ni(II) and Cu(II) have been synthesized and characterized. A study on their electrochemical, fluorescence and biological behaviour have also been performed. The complexes have been characterized on account of metal estimation studies, conductance behaviour, magnetic property, IR, UV-visible, EPR(Liquid nitrogen temperature) spectral studies and thermal analysis. The 1:2 metal : ligand complex formation is authenticated from the analytical data. Based on the various studies, the Co(II) complex has been recommended for octahedral geometry and a square planar geometry has been prompted for Cu(II) and Ni(II) complexes. The electro chemical property of the complexes have been studied by cyclic voltammetry. The Schiff base and its complexes have been scrutinized against bacterial and fungal pathogens. The complexes have been found to be more active than the Schiff base towards most of the pathogens studied. Invitro cytotoxicity of the copper complex of NMEPDHAPI has been screened against breast cancer cell lines (MCF-7). The IC50 value recommend that the copper complex has notable cytotoxicity against breast cancer cell line (MCF-7).

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