Effect of isotope scrambling and tunneling on the kinetic and product isotope effects for reduced nicotinamide adenine dinucleotide model hydride transfer reactions

Michael F. Powell; Thomas C. Bruice

doi:10.1021/ja00362a019

Effect of isotope scrambling and tunneling on the kinetic and product isotope effects for reduced nicotinamide adenine dinucleotide model hydride transfer reactions

Journal of the American Chemical Society ◽

10.1021/ja00362a019 ◽

1983 ◽

Vol 105 (24) ◽

pp. 7139-7149 ◽

Cited By ~ 68

Author(s):

Michael F. Powell ◽

Thomas C. Bruice

Keyword(s):

Nicotinamide Adenine Dinucleotide ◽

Isotope Effects ◽

Hydride Transfer ◽

Transfer Reactions ◽

Nicotinamide Adenine ◽

Hydride Transfer Reactions ◽

Reduced Nicotinamide Adenine Dinucleotide ◽

Product Isotope

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ChemInform Abstract: EFFECT OF ISOTOPE SCRAMBLING AND TUNNELING ON THE KINETIC AND PRODUCT ISOTOPE EFFECTS FOR REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE MODEL HYDRIDE TRANSFER REACTIONS

Chemischer Informationsdienst ◽

10.1002/chin.198409117 ◽

1984 ◽

Vol 15 (9) ◽

Author(s):

M. F. POWELL ◽

T. C. BRUICE

Keyword(s):

Nicotinamide Adenine Dinucleotide ◽

Isotope Effects ◽

Hydride Transfer ◽

Transfer Reactions ◽

Nicotinamide Adenine ◽

Hydride Transfer Reactions ◽

Reduced Nicotinamide Adenine Dinucleotide ◽

Product Isotope

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ChemInform Abstract: Energetics of Multistep versus One-Step Hydride Transfer Reactions of Reduced Nicotinamide Adenine Dinucleotide (NADH) Models with Organic Cations and p-Quinones.

ChemInform ◽

10.1002/chin.199904036 ◽

2010 ◽

Vol 30 (4) ◽

pp. no-no

Author(s):

J.-P. CHENG ◽

Y. LU ◽

X. ZHU ◽

L. MU

Keyword(s):

Nicotinamide Adenine Dinucleotide ◽

Hydride Transfer ◽

Transfer Reactions ◽

Nicotinamide Adenine ◽

Organic Cations ◽

One Step ◽

Hydride Transfer Reactions ◽

Reduced Nicotinamide Adenine Dinucleotide

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Energetics of Multistep versus One-step Hydride Transfer Reactions of Reduced Nicotinamide Adenine Dinucleotide (NADH) Models with Organic Cations andp-Quinones

The Journal of Organic Chemistry ◽

10.1021/jo9715985 ◽

1998 ◽

Vol 63 (18) ◽

pp. 6108-6114 ◽

Cited By ~ 53

Author(s):

Jin-Pei Cheng ◽

Yun Lu ◽

Xiaoqing Zhu ◽

Linjing Mu

Keyword(s):

Nicotinamide Adenine Dinucleotide ◽

Hydride Transfer ◽

Transfer Reactions ◽

Nicotinamide Adenine ◽

Organic Cations ◽

One Step ◽

Hydride Transfer Reactions ◽

Reduced Nicotinamide Adenine Dinucleotide

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Anomalous equilibrium and kinetic .alpha.-deuterium secondary isotope effects accompanying hydride transfer from reduced nicotinamide adenine dinucleotide

Journal of the American Chemical Society ◽

10.1021/ja00532a035 ◽

1980 ◽

Vol 102 (12) ◽

pp. 4198-4203 ◽

Cited By ~ 42

Author(s):

Linda C. Kurz ◽

Carl Frieden

Keyword(s):

Nicotinamide Adenine Dinucleotide ◽

Isotope Effects ◽

Hydride Transfer ◽

Nicotinamide Adenine ◽

Reduced Nicotinamide Adenine Dinucleotide

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ChemInform Abstract: ANOMALOUS EQUILIBRIUM AND KINETIC α-DEUTERIUM SECONDARY ISOTOPE EFFECTS ACCOMPANYING HYDRIDE TRANSFER FROM REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE

Chemischer Informationsdienst ◽

10.1002/chin.198036325 ◽

1980 ◽

Vol 11 (36) ◽

Author(s):

L. C. KURZ ◽

C. FRIEDEN

Keyword(s):

Nicotinamide Adenine Dinucleotide ◽

Isotope Effects ◽

Hydride Transfer ◽

Nicotinamide Adenine ◽

Reduced Nicotinamide Adenine Dinucleotide

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Substituent Effects on Temperature Dependence of Kinetic Isotope Effects in Hydride-Transfer Reactions of NADH/NAD+ Analogues in Solution: Reaction Center Rigidity Is the Key

Organic Letters ◽

10.1021/acs.orglett.0c02049 ◽

2020 ◽

Vol 22 (15) ◽

pp. 5963-5967

Author(s):

Peter Maness ◽

Shailendra Koirala ◽

Pratichhya Adhikari ◽

Nasim Salimraftar ◽

Yun Lu

Keyword(s):

Temperature Dependence ◽

Reaction Center ◽

Isotope Effects ◽

Substituent Effects ◽

Hydride Transfer ◽

Kinetic Isotope Effects ◽

Transfer Reactions ◽

Kinetic Isotope ◽

Solution Reaction ◽

Hydride Transfer Reactions

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Kinetic isotope effects on the oxidation of reduced nicotinamide adenine dinucleotide phosphate by the flavoprotein methylenetetrahydrofolate reductase

Biochemistry ◽

10.1021/bi00317a027 ◽

1984 ◽

Vol 23 (22) ◽

pp. 5272-5279 ◽

Cited By ~ 13

Author(s):

Maria A. Vanoni ◽

Rowena G. Matthews

Keyword(s):

Nicotinamide Adenine Dinucleotide ◽

Methylenetetrahydrofolate Reductase ◽

Isotope Effects ◽

Nicotinamide Adenine Dinucleotide Phosphate ◽

Kinetic Isotope Effects ◽

Nicotinamide Adenine ◽

Kinetic Isotope ◽

Reduced Nicotinamide Adenine Dinucleotide

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Steric Effects on the Primary Isotope Dependence of Secondary Kinetic Isotope Effects in Hydride Transfer Reactions in Solution: Caused by the Isotopically Different Tunneling Ready State Conformations?

Journal of the American Chemical Society ◽

10.1021/jacs.5b03085 ◽

2015 ◽

Vol 137 (20) ◽

pp. 6653-6661 ◽

Cited By ~ 11

Author(s):

Binita Maharjan ◽

Mahdi Raghibi Boroujeni ◽

Jonathan Lefton ◽

Ormacinda R. White ◽

Mortezaali Razzaghi ◽

...

Keyword(s):

Isotope Effects ◽

Hydride Transfer ◽

Kinetic Isotope Effects ◽

Transfer Reactions ◽

Steric Effects ◽

Kinetic Isotope ◽

Hydride Transfer Reactions

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Solvent effects on the temperature dependence of the primary kinetic isotope effects for hydride transfer reactions in solution

10.1021/scimeetings.0c05537 ◽

2020 ◽

Author(s):

Pratichhya Adhikari ◽

Shailendra Koirala

Keyword(s):

Temperature Dependence ◽

Solvent Effects ◽

Isotope Effects ◽

Hydride Transfer ◽

Kinetic Isotope Effects ◽

Transfer Reactions ◽

Kinetic Isotope ◽

Hydride Transfer Reactions

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Isotope Effects on Hydride Transfer Reactions from Transition Metal Hydrides to Trityl Cation. An Inverse Isotope Effect for a Hydride Transfer

Journal of the American Chemical Society ◽

10.1021/ja983448x ◽

1999 ◽

Vol 121 (13) ◽

pp. 3150-3155 ◽

Cited By ~ 40

Author(s):

Tan-Yun Cheng ◽

R. Morris Bullock

Keyword(s):

Transition Metal ◽

Isotope Effect ◽

Isotope Effects ◽

Metal Hydrides ◽

Hydride Transfer ◽

Transfer Reactions ◽

Transition Metal Hydrides ◽

Hydride Transfer Reactions ◽

Inverse Isotope Effect ◽

Trityl Cation

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