Routes to mitomycins. New syntheses of the 2,3,5,8-tetrahydro-5,8-dioxo-1H-pyrrolo[1,2-a]indole ring system. An efficient synthesis of 7-methoxymitosene

1983 ◽  
Vol 105 (9) ◽  
pp. 2859-2866 ◽  
Author(s):  
Jay R. Luly ◽  
Henry Rapoport
Keyword(s):  
Ring System ◽  
Indole Ring ◽  
Efficient Synthesis

scholarly journals (Z)-3-(1-Chloroprop-1-enyl)-2-methyl-1-phenylsulfonyl-1H-indole

2013 ◽  
Vol 69 (12) ◽  
pp. o1781-o1781 ◽  
Author(s):  
M. Umadevi ◽  
V. Saravanan ◽  
R. Yamuna ◽  
A. K. Mohanakrishnan ◽  
G. Chakkaravarthi
Keyword(s):  
Molecular Structure ◽  
Hydrogen Bond ◽  
Hydrogen Bonds ◽  
Phenyl Ring ◽  
Three Dimensional ◽  
Ring System ◽  
Indole Ring ◽  
Compound C ◽  
Dimensional Network ◽  
A Chain

In the title compound, C18H16ClNO2S, the indole ring system forms a dihedral angle of 75.07 (8)° with the phenyl ring. The molecular structure is stabilized by a weak intramolecular C—H...O hydrogen bond. In the crystal, molecules are linked by weak C—H...O hydrogen bonds, forming a chain along [10-1]. C—H...π interactions are also observed, leading to a three-dimensional network.

ChemInform Abstract: SYNTHESIS OF MACROCYCLIC LIGANDS CONTAINING THE INDOLE RING SYSTEM

1980 ◽  
Vol 11 (33) ◽  
Author(s):  
D. S. C. BLACK ◽  
N. E. ROTHNIE ◽  
L. C. H. WONG
Keyword(s):  
Ring System ◽  
Macrocyclic Ligands ◽  
Indole Ring

A novel and efficient synthesis of the aspidosperma alkaloid ring system: N(a)-benzyldeethylaspidospermidine

1985 ◽  
Vol 50 (26) ◽  
pp. 5517-5520 ◽  
Author(s):  
Jean-Claude Gramain ◽  
Henri Philippe Husson ◽  
Yves Troin
Keyword(s):  
Ring System ◽  
Efficient Synthesis

scholarly journals N-(1H-Indol-3-ylmethylidene)-4-methylpiperazin-1-amine

2013 ◽  
Vol 69 (11) ◽  
pp. o1706-o1706 ◽  
Author(s):  
Channappa N. Kavitha ◽  
Jerry P. Jasinski ◽  
Brian J. Anderson ◽  
H. S. Yathirajan ◽  
Manpreet Kaur
Keyword(s):  
Hydrogen Bonds ◽  
Dihedral Angle ◽  
Title Compound ◽  
Chair Conformation ◽  
Ring System ◽  
Indole Ring ◽  
Piperazine Ring ◽  
Compound C

In the title compound, C14H18N4, the piperazine ring is in a slightly distorted chair conformation. The indole ring system is twisted from the piperazine ring, making a dihedral angle of 7.27 (11)°. In the crystal, N—H...N hydrogen bonds link molecules into chains along [10-1].

scholarly journals 2-Bromo-1-(1-phenylsulfonyl-1H-indol-3-yl)propan-1-one

2014 ◽  
Vol 70 (3) ◽  
pp. o295-o296
Author(s):  
C. Ramathilagam ◽  
P. R. Umarani ◽  
V. Saravanan ◽  
A. K. Mohanakrishnan ◽  
B. Gunasekaran ◽  
...  
Keyword(s):  
Hydrogen Bonds ◽  
Dihedral Angle ◽  
Title Compound ◽  
Phenyl Ring ◽  
Ring System ◽  
Indole Ring ◽  
Methyl Group ◽  
Π Interactions ◽  
Compound C ◽  
A Chain

In the title compound, C17H14BrNO3S, the phenyl ring makes a dihedral angle of 89.78 (16)° with the plane of the indole ring system. The terminal Br atom and the methyl group are disordered over two sets of sites, with site occupancies of 0.860 (2) and 0.140 (2). In the crystal, molecules are linked into a chain along theb-axis direction by weak C—H...O hydrogen bonds. The chains are further linked by C—H...π interactions, forming layers parallel to thebcplane.

scholarly journals A Short and Efficient Synthesis of the [3]Triangulene Ring System

2019 ◽  
Vol 58 (44) ◽  
pp. 15793-15796 ◽  
Author(s):  
Carter J. Holt ◽  
Katelyn J. Wentworth ◽  
Richard P. Johnson
Keyword(s):  
Ring System ◽  
Efficient Synthesis

Efficient Synthesis of Some New 1,3,4‐Thiadiazoles and 1,2,4‐Triazoles Linked to Pyrazolylcoumarin Ring System as Potent 5α‐Reductase Inhibitors

2019 ◽  
Vol 56 (4) ◽  
pp. 1275-1282 ◽  
Author(s):  
Sobhi M. Gomha ◽  
Hassan M. Abdel-aziz ◽  
Mohamed G. Badrey ◽  
Mohamed M. Abdulla
Keyword(s):  
Ring System ◽  
Efficient Synthesis ◽  
Reductase Inhibitors

Synthesis of the new (cyclopenta [b]pyrrolo[1,2-d])azepino[4,5-b]indole ring system

1996 ◽  
Vol 37 (32) ◽  
pp. 5701-5704 ◽  
Author(s):  
Eric Noé ◽  
Denis Séraphin ◽  
Qiang Zhang ◽  
Frédéric Djaté ◽  
Jacques Hénin ◽  
...  
Keyword(s):  
Ring System ◽  
Indole Ring

scholarly journals Crystal structure and DFT study of (E)-N-[2-(1H-indol-3-yl)ethyl]-1-(anthracen-9-yl)methanimine

2017 ◽  
Vol 73 (9) ◽  
pp. 1329-1332
Author(s):  
Md. Serajul Haque Faizi ◽  
Necmi Dege ◽  
Sergey Malinkin ◽  
Tetyana Yu. Sliva
Keyword(s):  
Molecular Structure ◽  
Crystal Structure ◽  
Density Functional ◽  
Condensation Reaction ◽  
Ring System ◽  
Two Dimensional ◽  
Indole Ring ◽  
Functional Theory ◽  
Compound C ◽  
The Density Functional Theory

The title compound, C25H20N2, (I), was synthesized from the condensation reaction of anthracene-9-carbaldehyde and tryptamine in dry ethanol. The indole ring system (r.m.s. deviation = 0.016 Å) makes a dihedral angle of 63.56 (8)° with the anthracene ring (r.m.s. deviation = 0.023 Å). There is a short intramolecular C—H...N interaction present, and a C—H...π interaction involving the two ring systems. In the crystal, the indole H atom forms an intermolecular N—H...π interaction, linking molecules to form chains along theb-axis direction. There are also C—H...π interactions present, involving the central and terminal rings of the anthracene unit, linking the chains to form an overall two-dimensional layered structure, with the layers parallel to thebcplane. The density functional theory (DFT) optimized structure, at the B3LYP/6-311 G(d,p) level, is compared with the experimentally determined molecular structure in the solid state.

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