Simple general acid-base catalysis and virtual transition states for acetylcholinesterase-catalyzed hydrolysis of phenyl esters

1987 ◽  
Vol 109 (1) ◽  
pp. 239-245 ◽  
Author(s):  
Scott A. Acheson ◽  
Dimitra Dedopoulou ◽  
Daniel M. Quinn
Keyword(s):  
Transition States ◽  
Base Catalysis ◽  
Acid Base ◽  
General Acid ◽  
Hydrolysis Of

Do Enzymes Change the Nature of Transition States? Mapping the Transition State for General Acid−Base Catalysis of a Serine Protease‡

Biochemistry ◽  
2003 ◽  
Vol 42 (36) ◽  
pp. 10545-10553 ◽  
Author(s):  
Richard R. Bott ◽  
Gina Chan ◽  
Blanca Domingo ◽  
Grant Ganshaw ◽  
Constance Y. Hsia ◽  
...  
Keyword(s):  
Transition State ◽  
Serine Protease ◽  
Transition States ◽  
Base Catalysis ◽  
Acid Base ◽  
General Acid

Mechanism of hydrolysis of a thiazolium ion: General acid-base catalysis of the breakdown of the tetrahedral addition intermediate

1992 ◽  
Vol 20 (4) ◽  
pp. 296-312 ◽  
Author(s):  
Michael W. Washabaugh ◽  
Charles C. Yang ◽  
James T. Stivers ◽  
Kyung-Sang Lee
Keyword(s):  
Base Catalysis ◽  
Acid Base ◽  
General Acid ◽  
Mechanism Of Hydrolysis ◽  
Hydrolysis Of
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