Free energy component analysis: a study of the glutamic acid 165 .fwdarw. aspartic acid 165 mutation in triosephosphate isomerase

1989 ◽  
Vol 111 (21) ◽  
pp. 8247-8256 ◽  
Author(s):  
Valerie Daggett ◽  
Frank Brown ◽  
Peter Kollman
Keyword(s):  
Free Energy ◽  
Glutamic Acid ◽  
Aspartic Acid ◽  
Triosephosphate Isomerase ◽  
Component Analysis ◽  
Energy Component

Calculation of the Affinity of the λ Repressor-Operator Complex Based on Free Energy Component Analysis

2002 ◽  
Vol 28 (1-2) ◽  
pp. 187-211 ◽  
Author(s):  
David C. Kombo ◽  
B. Jayaram ◽  
Kevin J. McConnell ◽  
David L. Beveridge
Keyword(s):  
Free Energy ◽  
Component Analysis ◽  
Energy Component

Crystal Structure of the Mutant Yeast Triosephosphate Isomerase in Which the Catalytic Base Glutamic Acid 165 Is Changed to Aspartic Acid

Biochemistry ◽  
1994 ◽  
Vol 33 (10) ◽  
pp. 2824-2829 ◽  
Author(s):  
Diane Joseph-McCarthy ◽  
Linda E. Rost ◽  
Elizabeth A. Komives ◽  
Gregory A. Petsko
Keyword(s):  
Crystal Structure ◽  
Glutamic Acid ◽  
Aspartic Acid ◽  
Triosephosphate Isomerase

scholarly journals Dietary glutamic acid and aspartic acid as biomarkers for predicting diabetic retinopathy

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
So Young Park ◽  
Jieun Kim ◽  
Jung Il Son ◽  
Sang Youl Rhee ◽  
Do-Yeon Kim ◽  
...  
Keyword(s):  
Diabetic Retinopathy ◽  
Glutamic Acid ◽  
Aspartic Acid ◽  
Education Level ◽  
Screening Rate ◽  
Food Records ◽  
Acid Intake ◽  
Lower Education Level ◽  
Lower Education

AbstractThe screening rate of diabetic retinopathy (DR) is low despite the importance of early diagnosis. We investigated the predictive value of dietary glutamic acid and aspartic acid for diagnosis of DR using the Korea National Diabetes Program cohort study. The 2067 patients with type 2 diabetes without DR were included. The baseline intakes of energy, glutamic acid and aspartic acid were assessed using a 3-day food records. The risk of DR incidence based on intake of glutamic acid and aspartic acid was analyzed. The DR group was older, and had higher HbA1c, longer DM duration, lower education level and income than non-DR group (all p < 0.05). The intake of total energy, glutamic acid and aspartic acid were lower in DR group than non-DR group (p = 0.010, p = 0.025 and p = 0.042, respectively). There was no difference in the risk of developing DR according to the intake of glutamic acid and ascorbic acid. But, aspartic acid intake had a negative correlation with PDR. Hence, the intake of glutamic acid and aspartic acid did not affect in DR incidence. However, lower aspartic acid intake affected the PDR incidence.

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