Structure and properties of a pterin-containing ternary copper(II) complex, [Cu(bpy)(PC)(H2O)].cntdot.3H2O (bpy = 2,2'-bipyridine; PC = pterin-6-carboxylate). Implications for the active-site copper-cofactor bonding in Chromobacterium violaceum phenylalanine hydroxylase

Takamitsu Kohzuma; Hideki Masuda; Osamu Yamauchi

doi:10.1021/ja00191a052

Structure and properties of a pterin-containing ternary copper(II) complex, [Cu(bpy)(PC)(H2O)].cntdot.3H2O (bpy = 2,2'-bipyridine; PC = pterin-6-carboxylate). Implications for the active-site copper-cofactor bonding in Chromobacterium violaceum phenylalanine hydroxylase

Journal of the American Chemical Society ◽

10.1021/ja00191a052 ◽

1989 ◽

Vol 111 (9) ◽

pp. 3431-3433 ◽

Cited By ~ 40

Author(s):

Takamitsu Kohzuma ◽

Hideki Masuda ◽

Osamu Yamauchi

Keyword(s):

Active Site ◽

Phenylalanine Hydroxylase ◽

Chromobacterium Violaceum ◽

Structure And Properties

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Cloning and expression of Chromobacterium violaceum phenylalanine hydroxylase in Escherichia coli and comparison of amino acid sequence with mammalian aromatic amino acid hydroxylases.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)55083-3 ◽

1991 ◽

Vol 266 (28) ◽

pp. 18454-18459

Author(s):

A. Onishi ◽

L.J. Liotta ◽

S.J. Benkovic

Keyword(s):

Escherichia Coli ◽

Amino Acid ◽

Amino Acid Sequence ◽

Aromatic Amino Acid ◽

Phenylalanine Hydroxylase ◽

Chromobacterium Violaceum ◽

Cloning And Expression ◽

Aromatic Amino Acid Hydroxylases

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Structure Function Studies of the Phenylalanine Hydroxylase Active Site and a Summary of Structural Features

Advances in Experimental Medicine and Biology - Chemistry and Biology of Pteridines and Folates ◽

10.1007/978-1-4615-2960-6_10 ◽

1993 ◽

pp. 55-57 ◽

Cited By ~ 1

Author(s):

R. G. H. Cotton ◽

D. W. Howells ◽

J. A. Saleeba ◽

I. Dianzani ◽

P. M. Smooker ◽

...

Keyword(s):

Structure Function ◽

Active Site ◽

Phenylalanine Hydroxylase ◽

Structural Features

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Catalytic Ability Improvement of Phenylalanine Hydroxylase from Chromobacterium violaceum by N-Terminal Truncation and Proline Introduction

Journal of Microbiology and Biotechnology ◽

10.4014/jmb.1906.06060 ◽

2019 ◽

Vol 29 (9) ◽

pp. 1375-1382

Author(s):

Zhongmei Liu ◽

Zhongyi Cheng ◽

Shuangshuang Ye ◽

Li Zhou ◽

Zhemin Zhou

Keyword(s):

Phenylalanine Hydroxylase ◽

Chromobacterium Violaceum

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Investigations on the Active Site Models of [FeFe]-Hydrogenases: Synthesis, Structure, and Properties of N-Functionalized Azadithiolatodiiron Complexes Containing Mono- and Diphosphine Ligands

Organometallics ◽

10.1021/om700956e ◽

2008 ◽

Vol 27 (7) ◽

pp. 1409-1416 ◽

Cited By ~ 39

Author(s):

Li-Cheng Song ◽

Hu-Ting Wang ◽

Jian-Hua Ge ◽

Shu-Zhen Mei ◽

Jie Gao ◽

...

Keyword(s):

Active Site ◽

Diphosphine Ligands ◽

Structure And Properties

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The Accessibility of Iron at the Active Site of Recombinant Human Phenylalanine Hydroxylase to Water As Studied by1H NMR Paramagnetic Relaxation

Journal of Biological Chemistry ◽

10.1074/jbc.274.10.6280 ◽

1999 ◽

Vol 274 (10) ◽

pp. 6280-6284 ◽

Cited By ~ 11

Author(s):

Sigridur Olafsdottir ◽

Aurora Martı́nez

Keyword(s):

Active Site ◽

Phenylalanine Hydroxylase ◽

Paramagnetic Relaxation ◽

Human Phenylalanine Hydroxylase

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X-ray absorption studies of the copper-dependent phenylalanine hydroxylase from Chromobacterium violaceum. Comparison of the copper coordination in oxidized and dithionite-reduced enzymes. [Erratum to document cited in CA117(5):43463e]

Biochemistry ◽

10.1021/bi00086a036 ◽

1993 ◽

Vol 32 (35) ◽

pp. 9262-9262 ◽

Cited By ~ 1

Author(s):

Ninian J. Blackburn ◽

Richard W. Strange ◽

Robert T. Carr ◽

Stephen J. Benkovic

Keyword(s):

Phenylalanine Hydroxylase ◽

Chromobacterium Violaceum ◽

X Ray ◽

Copper Coordination ◽

Absorption Studies ◽

X Ray Absorption

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Regulatory properties of tetrahydrobiopterin cofactor bound at the active site of phenylalanine hydroxylase

Pteridines ◽

10.1515/pteridines.2000.11.2.34 ◽

2000 ◽

Vol 11 (2) ◽

pp. 34-36 ◽

Cited By ~ 1

Author(s):

Torgeir Flatmark ◽

Heidi Erlandsen ◽

Elisa Bjørgo ◽

Therese Solstad ◽

Anne P. Døskeland ◽

...

Keyword(s):

Active Site ◽

Phenylalanine Hydroxylase ◽

Regulatory Properties

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ChemInform Abstract: Structure and Properties of a Pterin-Containing Ternary Copper(II) Complex, (Cu(bpy)(PC)(H2O))·3 H2O (bpy: 2,2′-Bipyridine; PC: Pterin-6-carboxylate). Implications for the Active-Site Copper-Cofactor Bonding in Chromobacterium violace

ChemInform ◽

10.1002/chin.198932050 ◽

1989 ◽

Vol 20 (32) ◽

Author(s):

T. KOHZUMA ◽

H. MASUDA ◽

O. YAMAUCHI

Keyword(s):

Active Site ◽

Structure And Properties ◽

Abstract Structure

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Synthesis, Crystal Structure, and Properties of a Polyimidazole Diiron(III) Complex. A New Model of the Active Site of Purple Acid Phosphatase

Inorganic Chemistry ◽

10.1021/ic00113a020 ◽

1995 ◽

Vol 34 (9) ◽

pp. 2382-2388 ◽

Cited By ~ 30

Author(s):

Hanlin Nie ◽

Sheila Aubin ◽

Mark S. Mashuta ◽

Jimmy Wu ◽

John F. Richardson ◽

...

Keyword(s):

Crystal Structure ◽

Acid Phosphatase ◽

Active Site ◽

Purple Acid Phosphatase ◽

Structure And Properties ◽

New Model

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Structure and Properties of The Oxygen Donor

MRS Proceedings ◽

10.1557/proc-59-83 ◽

1985 ◽

Vol 59 ◽

Cited By ~ 12

Author(s):

L. C. Kimerling

Keyword(s):

Wave Function ◽

Electrical Activity ◽

Effective Mass ◽

Atomic Structure ◽

Active Site ◽

Aggregation Process ◽

Structure And Properties ◽

Oxygen Donor ◽

Heavily Doped ◽

Donor Character

ABSTRACTDuring aggregation, an assembly of oxygen atoms in silicon produces an electrically active site. The center is an effective mass, helium-like center (double donor) with a wave function of C2v symmetry. The formation reactions of the assembly reveal details of the invisible early stages of aggregation. The donor character of the center controls the aggregation process in heavily doped material. The atomic structure and the source of the electrical activity of the center remain unresolved.

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