Asymmetric reactions catalyzed by chiral metal complexes. 41. Highly efficient asymmetric hydrogenation of amino ketone derivatives leading to practical syntheses of (S)-propranolol and related compounds

Hisashi Takahashi; Shunji Sakuraba; Hideo Takeda; Kazuo Achiwa

doi:10.1021/ja00171a036

Asymmetric reactions catalyzed by chiral metal complexes. 41. Highly efficient asymmetric hydrogenation of amino ketone derivatives leading to practical syntheses of (S)-propranolol and related compounds

Journal of the American Chemical Society ◽

10.1021/ja00171a036 ◽

1990 ◽

Vol 112 (15) ◽

pp. 5876-5878 ◽

Cited By ~ 86

Author(s):

Hisashi Takahashi ◽

Shunji Sakuraba ◽

Hideo Takeda ◽

Kazuo Achiwa

Keyword(s):

Metal Complexes ◽

Asymmetric Hydrogenation ◽

Asymmetric Reactions ◽

Amino Ketone ◽

Highly Efficient ◽

Related Compounds

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ChemInform Abstract: Asymmetric Reactions Catalyzed by Chiral Metal Complexes. Part 65. Efficient Asymmetric Hydrogenation of α-Amino Ketone Derivatives. A Highly Enantioselective Synthesis of Phenylephrine, Levamisole, Carnitine and Propranolol.

ChemInform ◽

10.1002/chin.199545046 ◽

2010 ◽

Vol 26 (45) ◽

pp. no-no

Author(s):

S. SAKURABA ◽

H. TAKAHASHI ◽

H. TAKEDA ◽

K. ACHIWA

Keyword(s):

Metal Complexes ◽

Asymmetric Hydrogenation ◽

Enantioselective Synthesis ◽

Asymmetric Reactions ◽

Amino Ketone

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ChemInform Abstract: Asymmetric Reactions Catalyzed by Chiral Metal Complexes. Part 54. Efficient Asymmetric Hydrogenation of γ-Amino Ketone Hydrochloride Derivatives Catalyzed by (2S,4S)-4-Dicyclohexylphosphino- 2-diphenylphosphinomethyl-1-(methylcarbamo

ChemInform ◽

10.1002/chin.199323069 ◽

2010 ◽

Vol 24 (23) ◽

pp. no-no

Author(s):

S. SAKURABA ◽

N. NAKAJIMA ◽

K. ACHIWA

Keyword(s):

Metal Complexes ◽

Asymmetric Hydrogenation ◽

Asymmetric Reactions ◽

Amino Ketone

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ChemInform Abstract: Asymmetric Reactions Catalyzed by Chiral Metal Complexes. Part 66. Efficient Asymmetric Hydrogenation of β- and γ-Amino Ketone Derivatives Leading to Practical Synthesis of Fluoxetine and Eprozinol.

ChemInform ◽

10.1002/chin.199545047 ◽

2010 ◽

Vol 26 (45) ◽

pp. no-no

Author(s):

S. SAKURABA ◽

K. ACHIWA

Keyword(s):

Metal Complexes ◽

Asymmetric Hydrogenation ◽

Asymmetric Reactions ◽

Amino Ketone ◽

Practical Synthesis

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ChemInform Abstract: Highly Efficient Asymmetric Hydrogenation of Amino Ketone Derivatives Leading to Practical Syntheses of (S)-Propranolol and Related Compounds.

ChemInform ◽

10.1002/chin.199046114 ◽

1990 ◽

Vol 21 (46) ◽

Author(s):

H. TAKAHASHI ◽

S. SAKURABA ◽

H. TAKEDA ◽

K. ACHIWA

Keyword(s):

Asymmetric Hydrogenation ◽

Amino Ketone ◽

Highly Efficient ◽

Related Compounds

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Asymmetric Reactions Catalyzed by Chiral Metal Complexes. LII. The origin of the enantioselection in the ruthenium(II)-catalyzed asymmetric hydrogenation of .ALPHA.,.BETA.-unsaturated carboxylic acid.

Chemical and Pharmaceutical Bulletin ◽

10.1248/cpb.40.1072 ◽

1992 ◽

Vol 40 (4) ◽

pp. 1072-1074 ◽

Cited By ~ 7

Author(s):

Kiyoshi YOSHIKAWA ◽

Masanao MURATA ◽

Naoko YAMAMOTO ◽

Kiyoshi INOGUCHI ◽

Kazuo ACHIWA

Keyword(s):

Carboxylic Acid ◽

Metal Complexes ◽

Asymmetric Hydrogenation ◽

Asymmetric Reactions ◽

Unsaturated Carboxylic Acid ◽

Alpha Beta

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ChemInform Abstract: Asymmetric Reactions Catalyzed by Chiral Metal Complexes. Part 42. Development of a New Six-Membered Chelating Chiral (Bisphosphine) rhodium Catalyst and Efficient Asymmetric Hydrogenation of (Z)-2- Acetamidocinnamic Acid.

ChemInform ◽

10.1002/chin.199121266 ◽

2010 ◽

Vol 22 (21) ◽

pp. no-no

Author(s):

K. INOGUCHI ◽

K. ACHIWA

Keyword(s):

Metal Complexes ◽

Asymmetric Hydrogenation ◽

Rhodium Catalyst ◽

Asymmetric Reactions

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ChemInform Abstract: Asymmetric Reactions Catalyzed by Chiral Metal Complexes. Part 55. Efficient Asymmetric Syntheses of Naturally Occurring Lignan Lactones Using Catalytic Asymmetric Hydrogenation as a Key Reaction.

ChemInform ◽

10.1002/chin.199325275 ◽

2010 ◽

Vol 24 (25) ◽

pp. no-no

Author(s):

T. MORIMOTO ◽

M. CHIBA ◽

K. ACHIWA

Keyword(s):

Metal Complexes ◽

Asymmetric Hydrogenation ◽

Asymmetric Reactions ◽

Asymmetric Syntheses ◽

Naturally Occurring ◽

Catalytic Asymmetric ◽

Catalytic Asymmetric Hydrogenation

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ChemInform Abstract: Asymmetric Reactions Catalyzed by Chiral Metal Complexes. Part 51. A New Type of Atropisomeric Biphenylbisphosphine Ligand, (R)-MOC-BIMOP and Its Use in Efficient Asymmetric Hydrogenation of α- Aminoketone and Itaconic Acid.

ChemInform ◽

10.1002/chin.199217039 ◽

2010 ◽

Vol 23 (17) ◽

pp. no-no

Author(s):

K. YOSHIKAWA ◽

N. YAMAMOTO ◽

M. MURATA ◽

K. AWANO ◽

T. MORIMOTO ◽

...

Keyword(s):

Metal Complexes ◽

Itaconic Acid ◽

Asymmetric Hydrogenation ◽

Asymmetric Reactions ◽

New Type

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ChemInform Abstract: Asymmetric Reactions Catalyzed by Chiral Metal Complexes. Part 64. Synthesis of a New Chiral Bisphosphine Ligand, MOCBP, and Its Use in Rhodium(I)-Catalyzed Asymmetric Hydrogenation of a Cyclic Enamide.

ChemInform ◽

10.1002/chin.199527188 ◽

2010 ◽

Vol 26 (27) ◽

pp. no-no

Author(s):

T. MORIMOTO ◽

N. NAKAJIMA ◽

K. ACHIWA

Keyword(s):

Metal Complexes ◽

Asymmetric Hydrogenation ◽

Asymmetric Reactions ◽

Chiral Bisphosphine Ligand

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ChemInform Abstract: Asymmetric Reactions Catalyzed by Chiral Metal Complexes. Part 45. Efficient Preparation of Optically Active (S)-(-)-3-Methyl-γ- butyrolactone by Catalytic Asymmetric Hydrogenation Using Chiral N- Substituted Pyrrolidinebisphosphinerh

ChemInform ◽

10.1002/chin.199219158 ◽

2010 ◽

Vol 23 (19) ◽

pp. no-no

Author(s):

H. TAKEDA ◽

T. TACHINAMI ◽

S. HOSOKAWA ◽

M. ABURATANI ◽

K. INOGUCHI ◽

...

Keyword(s):

Metal Complexes ◽

Asymmetric Hydrogenation ◽

Optically Active ◽

Asymmetric Reactions ◽

Catalytic Asymmetric ◽

Catalytic Asymmetric Hydrogenation

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