Raman spectral studies of nucleic acids. 36. Structure in solution of the RNA.cntdot.DNA hybrid (rA)8.cntdot.(dT)8 determined by NMR and Raman spectroscopy

1990 ◽  
Vol 112 (11) ◽  
pp. 4508-4512 ◽  
Author(s):  
Masato Katahira ◽  
Sang Jong Lee ◽  
Yuji Kobayashi ◽  
Hiromu Sugeta ◽  
Yoshimasa Kyogoku ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Nucleic Acids ◽  
Spectral Studies ◽  
Raman Spectral ◽  
Structure In Solution

Vibrational spectral studies of solutions at elevated temperatures and pressures. 11. A Raman spectral study of aqueous iron(III) chloride solutions between 25 and 300 °C

1989 ◽  
Vol 67 (3) ◽  
pp. 517-524 ◽  
Author(s):  
Katsuo Murata ◽  
Donald E. Irish ◽  
Gerald E. Toogood
Keyword(s):  
Raman Spectroscopy ◽  
Dielectric Constant ◽  
Dominant Species ◽  
Elevated Temperatures ◽  
Spectral Studies ◽  
Iron Species ◽  
Chloride Solutions ◽  
Increasing Temperature ◽  
Raman Spectral ◽  
Temperature Factors

The Raman spectra of acidified aqueous iron(III) chloride solutions have been measured between 25 and 300 °C. When Fe3+ concentrations are in the range 0.75 to 1.0 mol kg−1 and Cl−/Fe3+ ratios, R, in the range 3 to 9.5, the dominant species at 25 °C is trans-[Fe(H2O)4Cl2]+; at 300 °C the sole iron-containing species is tetrahedral [Formula: see text]. Conversion of [Fe(H2O)4Cl2]+ into [Formula: see text] appears not to involve intermediate iron species. In the presence of excess chloride the reaction [Formula: see text] is presumed to occur; ΔH for this reaction has been estimated as +65 ± 8 kJ mol−1. In addition to increasing temperature, factors which favour [Formula: see text] over other iron species include increasing acidity, increasing R, and decreasing dielectric constant. Keywords: high temperature aqueous solutions, iron(III) chloride, Raman spectroscopy.

scholarly journals Raman-spectral studies of nucleic acids XVII. Conformational structures of polyinosinic acid

1977 ◽  
Vol 4 (7) ◽  
pp. 2407-2420 ◽  
Author(s):  
C. H. Chou ◽  
G. J. Thomas ◽  
Struther Arnott ◽  
P. J. Campbell Smith
Keyword(s):  
Nucleic Acids ◽  
Spectral Studies ◽  
Polyinosinic Acid ◽  
Raman Spectral

Raman Spectral Studies of 2-Mercaptobenzothiazole Accelerator Systems

1974 ◽  
Vol 47 (4) ◽  
pp. 911-923 ◽  
Author(s):  
R. S. Kapur ◽  
J. L. Koenig ◽  
J. R. Shelton
Keyword(s):  
Raman Spectroscopy ◽  
Laser Raman Spectroscopy ◽  
Spectral Studies ◽  
Significant Evidence ◽  
Laser Raman ◽  
Raman Spectral

Abstract A mechanism for the formation of the rubber-bound intermediate in the vulcanization of elastomers has been proposed. The active sulfurating agent is a polysulfide. Laser Raman spectroscopy has been used to provide significant evidence for this mechanism in the presence of cis-1,4-poly(butadiene).

scholarly journals Indication of high lipid content in epithelial-mesenchymal transitions of breast tissues

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Siti Norbaini Sabtu ◽  
S. F. Abdul Sani ◽  
L. M. Looi ◽  
S. F. Chiew ◽  
Dharini Pathmanathan ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Raman Spectroscopy ◽  
Multivariate Analysis ◽  
Nucleic Acids ◽  
Raman Spectra ◽  
Cancer Progression ◽  
Component Analysis ◽  
Breast Cancer Tissue ◽  
Metabolic Changes ◽  
Cancer Tissue

AbstractThe epithelial-mesenchymal transition (EMT) is a crucial process in cancer progression and metastasis. Study of metabolic changes during the EMT process is important in seeking to understand the biochemical changes associated with cancer progression, not least in scoping for therapeutic strategies aimed at targeting EMT. Due to the potential for high sensitivity and specificity, Raman spectroscopy was used here to study the metabolic changes associated with EMT in human breast cancer tissue. For Raman spectroscopy measurements, tissue from 23 patients were collected, comprising non-lesional, EMT and non-EMT formalin-fixed and paraffin embedded breast cancer samples. Analysis was made in the fingerprint Raman spectra region (600–1800 cm−1) best associated with cancer progression biochemical changes in lipid, protein and nucleic acids. The ANOVA test followed by the Tukey’s multiple comparisons test were conducted to see if there existed differences between non-lesional, EMT and non-EMT breast tissue for Raman spectroscopy measurements. Results revealed that significant differences were evident in terms of intensity between the non-lesional and EMT samples, as well as the EMT and non-EMT samples. Multivariate analysis involving independent component analysis, Principal component analysis and non-negative least square were used to analyse the Raman spectra data. The results show significant differences between EMT and non-EMT cancers in lipid, protein, and nucleic acids. This study demonstrated the capability of Raman spectroscopy supported by multivariate analysis in analysing metabolic changes in EMT breast cancer tissue.

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