SN2 and AdN-E Mechanisms in Bimolecular Nucleophilic Substitutions at Vinyl Carbon. The Relevance of the LUMO Symmetry of the Electrophile

1995 ◽  
Vol 117 (8) ◽  
pp. 2297-2300 ◽  
Author(s):  
Vittorio Lucchini ◽  
Giorgio Modena ◽  
Lucia Pasquato
Keyword(s):  
Nucleophilic Substitutions ◽  
Vinyl Carbon

scholarly journals Circular linkage of intramolecular multi-hydrogen bonding frameworks through nucleophilic substitutions of β-dicarbonyls onto cyanuric chloride and subsequent tautomerisation

RSC Advances ◽  
2020 ◽  
Vol 10 (64) ◽  
pp. 39033-39036
Author(s):  
Ayano Awatani ◽  
Masaaki Suzuki
Keyword(s):  
Hydrogen Bonding ◽  
Cyanuric Chloride ◽  
Nucleophilic Substitutions ◽  
Hydrogen Bonding Interactions ◽  
Triazine Derivatives

Triply β-dicarbonyl-embedded 1,3,5-triazine derivatives result in formation of circular linkage of resonance-assisted hydrogen bonding interactions, which can be regarded as well-delocalized resonance hybrids.

scholarly journals Biocatalysis with Laccases: An Updated Overview

Catalysts ◽  
2020 ◽  
Vol 11 (1) ◽  
pp. 26
Author(s):  
Ivan Bassanini ◽  
Erica Elisa Ferrandi ◽  
Sergio Riva ◽  
Daniela Monti
Keyword(s):  
Organic Synthesis ◽  
Alcohol Oxidation ◽  
Industrial Processes ◽  
Organic Substrates ◽  
Fine Chemicals ◽  
Multicopper Oxidases ◽  
Carbohydrate Chemistry ◽  
Nucleophilic Substitutions ◽  
Mediator System ◽  
Integrated Processes

Laccases are multicopper oxidases, which have been widely investigated in recent decades thanks to their ability to oxidize organic substrates to the corresponding radicals while producing water at the expense of molecular oxygen. Besides their successful (bio)technological applications, for example, in textile, petrochemical, and detoxifications/bioremediations industrial processes, their synthetic potentialities for the mild and green preparation or selective modification of fine chemicals are of outstanding value in biocatalyzed organic synthesis. Accordingly, this review is focused on reporting and rationalizing some of the most recent and interesting synthetic exploitations of laccases. Applications of the so-called laccase-mediator system (LMS) for alcohol oxidation are discussed with a focus on carbohydrate chemistry and natural products modification as well as on bio- and chemo-integrated processes. The laccase-catalyzed Csp2-H bonds activation via monoelectronic oxidation is also discussed by reporting examples of enzymatic C-C and C-O radical homo- and hetero-couplings, as well as of aromatic nucleophilic substitutions of hydroquinones or quinoids. Finally, the laccase-initiated domino/cascade synthesis of valuable aromatic (hetero)cycles, elegant strategies widely documented in the literature across more than three decades, is also presented.

Some nucleophilic substitutions in 2,4-and 2,4,8-trichloro-pyrido [3,2-d] pyrimidines

1989 ◽  
Vol 12 (1) ◽  
pp. 8-11
Author(s):  
Said M. Boyomi ◽  
Abdel-Kader M. Ismaiel ◽  
Hassan M. Eisa ◽  
Mohmed M. El-Kerdawy
Keyword(s):  
Nucleophilic Substitutions

ChemInform Abstract: α-Fluorohydrazones as Useful Precursors in Nucleophilic Substitutions.

ChemInform ◽  
2013 ◽  
Vol 44 (46) ◽  
pp. no-no
Author(s):  
Ryota Yunoki ◽  
Atsushi Yajima ◽  
Tsuyoshi Taniguchi ◽  
Hiroyuki Ishibashi
Keyword(s):  
Nucleophilic Substitutions

Nucleophilic substitutions of 2-chloronaphtho[2,3-b]furan-4,9-dione with amines

1998 ◽  
Vol 35 (2) ◽  
pp. 301-305 ◽  
Author(s):  
Jyunichi Koyanagi ◽  
Masayuki Ogawa ◽  
Katsumi Yamamoto ◽  
Kouji Nakayama ◽  
Akira Tanaka
Keyword(s):  
Nucleophilic Substitutions

Optimization of Micellar Catalysis of Nucleophilic Substitutions in Buffered Cetyltrimethylammonium Salt Solutions. 1. Buffers for the 9−10 pH Range†

Langmuir ◽  
2000 ◽  
Vol 16 (5) ◽  
pp. 2157-2163 ◽  
Author(s):  
Nadia Ouarti ◽  
Antonio Marques ◽  
Iva Blagoeva ◽  
Marie-Françoise Ruasse
Keyword(s):  
Micellar Catalysis ◽  
Salt Solutions ◽  
Nucleophilic Substitutions ◽  
Ph Range
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